scholarly journals Parasitological Clearance Rates and Drug Concentrations of a Fixed Dose Combination of Azithromycin-Chloroquine in Asymptomatic Pregnant Women with Plasmodium Falciparum Parasitemia: An Open-Label, Non-Comparative Study in Sub-Saharan Africa

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0165692 ◽  
Author(s):  
Kamija Phiri ◽  
Joshua Kimani ◽  
George A. Mtove ◽  
Qinying Zhao ◽  
Ricardo Rojo ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Comparative Study ◽  
Pregnant Women ◽  
Sub Saharan Africa ◽  
Fixed Dose ◽  
Clearance Rates ◽  
Open Label ◽  
Drug Concentrations ◽  
Dose Combination ◽  
Sub Saharan

scholarly journals Asexual and sexual stages of Plasmodium falciparum in Nigerian pregnant women attending antenatal booking clinic

2010 ◽  
Vol 3 (3) ◽  
pp. 106-109 ◽  
Author(s):  
S T Balogun ◽  
F A Fehintola ◽  
O A Adeyanju ◽  
A A Adedeji
Keyword(s):  
Plasmodium Falciparum ◽  
Preterm Birth ◽  
Infant Mortality ◽  
Pregnant Women ◽  
Blood Meal ◽  
Sub Saharan Africa ◽  
Female Mosquito ◽  
Susceptibility To Infection ◽  
Sexual Stages ◽  
Sub Saharan

Susceptibility to infection by Plasmodium falciparum is increased in pregnant women. In sub-Saharan Africa, the consequences of maternal malaria include preterm birth, fetal growth restriction and increased infant mortality. Malaria transmission requires the circulation of viable gametocytes that can be ingested by the female mosquito taking a blood meal. This study was conducted to evaluate the presence of asexual and sexual stages of P. falciparum in pregnant women attending antenatal booking clinics in south-western Nigeria, an area hyper-endemic for malaria. Gametocyte carriage was about 13%, similar to that documented for children symptomatic for malaria in our area of study.

scholarly journals Asymptomatic Malaria Correlates with Anaemia in Pregnant Women at Ouagadougou, Burkina Faso

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Zoenabo Douamba ◽  
Cyrille Bisseye ◽  
Florencia W. Djigma ◽  
Tegwinde R. Compaoré ◽  
Valérie Jean Telesphore Bazie ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Pregnant Women ◽  
Rapid Detection ◽  
Intermittent Preventive Treatment ◽  
Preventive Treatment ◽  
Asymptomatic Infection ◽  
Sub Saharan Africa ◽  
Asymptomatic Malaria ◽  
Low Levels ◽  
Sub Saharan

Sub-Saharan Africa records each year about thirty-two million pregnant women living in areas of high transmission ofPlasmodium falciparumcausing malaria. The aim of this study was to carve out the prevalence of asymptomatic malaria among pregnant women and to emphasize its influence on haematological markers. The prevalence ofPlasmodium falciparumasymptomatic infection among pregnant women was 30% and 24% with rapid detection test (RDT) and microscopy, respectively. The prevalence ofP. falciparumasymptomatic malaria was reduced among pregnant women using sulfadoxine-pyrimethamine's intermittent preventive treatment and 61% of them were anaemic. Anaemia was significantly more common in women infected withP. falciparumcompared with the uninfected pregnant women. Most of the women had normal levels of homocysteine and low levels of folate, respectively. Therefore, the systematic diagnosis of malaria should be introduced to pregnant women as a part of the antenatal care.

Malaria

2021 ◽  
pp. 227-248
Author(s):  
Frank Baiden ◽  
Keziah L. Malm ◽  
Fred Binka
Keyword(s):  
Plasmodium Falciparum ◽  
Pregnant Women ◽  
Neurological Deficit ◽  
Diagnostic Tests ◽  
Point Of Care ◽  
Rapid Diagnostic Tests ◽  
Sub Saharan Africa ◽  
Protozoan Infection ◽  
Life Threatening ◽  
Sub Saharan

Malaria is a subtropical and tropical protozoan infection that accounts for nearly half a million deaths each year. Most deaths occur in sub-Saharan Africa and are caused by Plasmodium falciparum. The least studied of the five Plasmodia species that cause malaria, P. knowlesi, along with P. vivax cause life-threatening disease, mostly in Southeast Asia. Children, pregnant women, and non-immune travellers to endemic countries are most vulnerable to severe malaria. Cerebral malaria and anaemia are complications that results in neurological deficit and death if treatment is delayed or inappropriately administered. Rapid diagnostic tests have emerged as accurate and reliable means to diagnosing malaria at point-of-care.

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