scholarly journals Differential expression of genes identified by suppression subtractive hybridization in liver and adipose tissue of gerbils with diabetes

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0191212 ◽  
Author(s):  
Jingjing Gong ◽  
Xiaoyan Du ◽  
Zhenkun Li ◽  
Xiaohong Li ◽  
Meng Guo ◽  
...  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Carmen P. Wong ◽  
Urszula T. Iwaniec ◽  
Russell T. Turner

AbstractSixteen-week-old female C57BL/6J mice were sacrificed aboard the International Space Station after 37 days of flight (RR-1 mission) and frozen carcasses returned to Earth. RNA was isolated from interscapular brown adipose tissue (BAT) and gonadal white adipose tissue (WAT). Spaceflight resulted in differential expression of genes in BAT consistent with increased non-shivering thermogenesis and differential expression of genes in WAT consistent with increased glucose uptake and metabolism, adipogenesis, and β-oxidation.


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