Paternal indifference and neglect in early life and creativity: Exploring the moderating role of TPH1 genotype and offspring gender

AbstractFor further understanding the joint contribution of environment, heredity and gender to creativity, the present research examined the prospective impact of paternal indifference & neglect in early life, TPH1 rs623580, offspring’s gender, and the interaction effects thereof on creativity in five hundred and thirty-nine unrelated healthy Chinese undergraduate students. Paternal indifference & neglect in early life was assessed on the Parental Bonding Instrument (PBI) and creativity on the Runco Creativity Assessment Battery (rCAB). Results showed significant paternal indifference & neglect × TPH1 genotype and TPH1 genotype × offspring’s gender interaction effects when predicting creativity. Specifically, paternal indifference & neglect in early life negatively predicted creativity in youth when individuals carry A allele of TPH1 (rs623580). In addition, male individuals who carry A allele were linked with lower level of flexibility compared to TT homozygote individuals. No significant three-way interaction was found. Findings from the current study suggested that the A allele of TPH1 (rs623580) might be a risk allele for creativity, and the long-term negative influence of paternal indifference & neglect in early life on individuals’ creativity in youth depending on TPH1 genotype.

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T46. The Moderating Role of Age in the Relationship Between Early Life Adversity and Hair Cortisol Concentrations in Adults Admitted to a Psychiatric Emergency Service

Biological Psychiatry ◽

10.1016/j.biopsych.2019.03.369 ◽

2019 ◽

Vol 85 (10) ◽

pp. S146-S147

Author(s):

Marie-France Marin ◽

Steve Geoffrion ◽

Charles-Edouard Giguère ◽

Signature Consortium

Keyword(s):

Early Life ◽

Emergency Service ◽

Psychiatric Emergency ◽

Hair Cortisol ◽

Early Life Adversity ◽

Psychiatric Emergency Service ◽

The Relationship ◽

Moderating Role

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Testing the Strain Theory of Suicide – The Moderating Role of Social Support

Crisis ◽

10.1027/0227-5910/a000604 ◽

2020 ◽

Vol 41 (2) ◽

pp. 82-88 ◽

Cited By ~ 1

Author(s):

Bob Lew ◽

Ksenia Chistopolskaya ◽

Yanzheng Liu ◽

Mansor Abu Talib ◽

Olga Mitina ◽

...

Keyword(s):

Social Support ◽

Suicidal Behavior ◽

Online Survey ◽

Perceived Social Support ◽

Strain Theory ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Psychological Strains ◽

Moderating Role

Abstract. Background: According to the strain theory of suicide, strains, resulting from conﬂicting and competing pressures in an individual's life, are hypothesized to precede suicide. But social support is an important factor that can mitigate strains and lessen their input in suicidal behavior. Aims: This study was designed to assess the moderating role of social support in the relation between strain and suicidality. Methods: A sample of 1,051 employees were recruited in Beijing, the capital of China, through an online survey. Moderation analysis was performed using SPSS PROCESS Macro. Social support was measured with the Multidimensional Scale of Perceived Social Support, and strains were assessed with the Psychological Strains Scale. Results: Psychological strains are a good predictor of suicidality, and social support, a basic need for each human being, moderates and decreases the effects of psychological strains on suicidality. Limitations: The cross-sectional survey limited the extent to which conclusions about causal relationships can be drawn. Furthermore, the results may not be generalized to the whole of China because of its diversity. Conclusion: Social support has a tendency to mitigate the effects of psychological strains on suicidality.

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