scholarly journals Modifying and validating the social responsiveness scale edition 2 for use with deaf children and young people

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243162
Author(s):  
Barry Wright ◽  
Helen Phillips ◽  
Ann Le Couteur ◽  
Jennifer Sweetman ◽  
Rachel Hodkinson ◽  
...  

A Delphi consensus methodology was used to adapt a screening tool, the Social Responsiveness Scale– 2 (SRS-2), for use with deaf children including those whose preferred communication method is sign language. Using this approach; 27 international experts (The Delphi International Expert Panel), on the topic of autism spectrum disorder (ASD) in deaf people, contributed to the review of item content. A criterion for agreement was set at 80% of experts on each item (with 75% acceptable in the final fourth round). The agreed modifications are discussed. The modified SRS-2 research adaptation for deaf people (referred to here as the “SRS-2 Deaf adaptation”) was then translated into British Sign Language using a robust translation methodology and validated in England in a sample of 198 deaf children, 76 with Autism Spectrum Disorders (ASD) and 122 without ASD. The SRS-2 Deaf adaptation was compared blind to a NICE (National Institute for Health and Care Excellence) guideline standard clinical assessment. The area under the Receiver Operating (ROC) curve was 0.811 (95% CI: 0.753, 0.869), with an optimal cut-off value of 73, which gave a sensitivity of 82% and a specificity of 67%. The Cronbach Alpha coefficient was 0.968 suggesting high internal consistency. The Intraclass Correlation Coefficient was 0.897, supporting test-retest reliability. This performance is equivalent to similar instruments used for screening ASD in the hearing population.

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0235946
Author(s):  
Z. Kovacs Balint ◽  
J. Raper ◽  
V. Michopoulos ◽  
L. H. Howell ◽  
C. Gunter ◽  
...  

Primates form strong social bonds and depend on social relationships and networks that provide shared resources and protection critical for survival. Social deficits such as those present in autism spectrum disorder (ASD) and other psychiatric disorders hinder the individual’s functioning in communities. Given that early diagnosis and intervention can improve outcomes and trajectories of ASD, there is a great need for tools to identify early markers for screening/diagnosis, and for translational animal models to uncover biological mechanisms and develop treatments. One of the most widely used screening tools for ASD in children is the Social Responsiveness Scale (SRS), a quantitative measure used to identify individuals with atypical social behaviors. The SRS has been adapted for use in adult rhesus monkeys (Macaca mulatta)–a species very close to humans in terms of social behavior, brain anatomy/connectivity and development–but has not yet been validated or adapted for a necessary downward extension to younger ages matching those for ASD diagnosis in children. The goal of the present study was to adapt and validate the adult macaque SRS (mSRS) in juvenile macaques with age equivalent to mid-childhood in humans. Expert primate coders modified the mSRS to adapt it to rate atypical social behaviors in juvenile macaques living in complex social groups at the Yerkes National Primate Research Center. Construct and face validity of this juvenile mSRS (jmSRS) was determined based on well-established and operationalized measures of social and non-social behaviors in this species using traditional behavioral observations. We found that the jmSRS identifies variability in social responsiveness of juvenile rhesus monkeys and shows strong construct/predictive validity, as well as sensitivity to detect atypical social behaviors in young male and female macaques across social status. Thus, the jmSRS provides a promising tool for translational research on macaque models of children social disorders.


Author(s):  
Zahra Shahrivar ◽  
Mehdi Tehrani-Doost ◽  
Elham Davoodi ◽  
Tanaz Hosseiniani ◽  
Helia Tarighatnia ◽  
...  

Objective: The Social Responsiveness Scale-2 (SRS-2) is a well-known screening instrument to assess autistic spectrum symptoms quantitatively. This study assessed the different types of reliability of the Farsi translation of the scale. Method: This scale was translated into Farsi and back translated considering all aspects of methodology in translation. Then, based on stratified sampling, 533 7-11-year-old students were randomly selected from the mainstream schools located in the central parts of Tehran, the capital of Iran. For all the students, SRS-2 was completed by both the parents and teachers. To check retest reliability, the test was administered again for 15% of the total participants after a 2-4 week-period. Cronbach’s alpha coefficient, split-half” and Gottman” methods, and intra-class correlation coefficient (ICC) were used. Results: The mean total raw score was 48.47 (±23.63) and 53.17 (±27.33) in the sequence of the parents and teachers’ reports. The internal consistency (Cronbach’s alpha; 0.86 and 0.89), test-retest reliability (ICC; 0.72 and 0.83 for parents and teacher’ ratings, respectively), and interrater reliability (ICC; 0.72) showed well-accepted measurement performance. Conclusion: The findings indicated that the Farsi SRS-2 can be used as a reliable instrument to measure social responsiveness as autistic symptoms in Iranian child population.


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