scholarly journals Gastric examination using a novel three-dimensional magnetically assisted capsule endoscope and a hand-held magnetic controller: A porcine model study

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0256519
Author(s):  
Dong Jun Oh ◽  
Ji Hyung Nam ◽  
Junseok Park ◽  
Youngbae Hwang ◽  
Yun Jeong Lim
Keyword(s):  
Animal Experiment ◽  
Porcine Model ◽  
Three Dimensional ◽  
Lesion Size ◽  
Mass Lesion ◽  
Upper Endoscopy ◽  
Gastric Lesions ◽  
Model Study ◽  
Lesser Curvature ◽  
Magnetically Assisted

Magnetically assisted capsule endoscopy (MACE) is a noninvasive procedure and can overcome passive capsule movement that limits gastric examination. MACE has been studied in many trials as an alternative to upper endoscopy. However, to increase diagnostic accuracy of various gastric lesions, MACE should be able to provide stereoscopic, clear images and to measure the size of a lesion. So, we conducted the animal experiment using a novel three-dimensional (3D) MACE and a new hand-held magnetic controller for gastric examination. The purpose of this study is to assess the performance and safety of 3D MACE and hand-held magnetic controller through the animal experiment. Subsequently, via the dedicated viewer, we evaluate whether 3D reconstruction images and clear images can be obtained and accurate lesion size can be measured. During real-time gastric examination, the maneuverability and visualization of 3D MACE were adequate. A polypoid mass lesion was incidentally observed at the lesser curvature side of the prepyloric antrum. The mass lesion was estimated to be 10.9 x 11.5 mm in the dedicated viewer, nearly the same size and shape as confirmed by upper endoscopy and postmortem examination. Also, 3D and clear images of the lesion were successfully reconstructed. This animal experiment demonstrates the accuracy and safety of 3D MACE. Further clinical studies are warranted to confirm the feasibility of 3D MACE for human gastric examination.

ID: 3492600 GASTRIC EXAMINATION USING A NOVEL THREE-DIMENSIONAL MAGNETICALLY ASSISTED CAPSULE ENDOSCOPY WITH A HAND-HELD MAGNETIC CONTROLLER: A PORCINE MODEL

2021 ◽  
Vol 93 (6) ◽  
pp. AB200
Author(s):  
Yun Jeong Lim ◽  
Ji Hyung Nam ◽  
Dong Jun Oh ◽  
Kwang Seop Kim ◽  
Junseok Park ◽  
...  
Keyword(s):  
Capsule Endoscopy ◽  
Porcine Model ◽  
Three Dimensional ◽  
Magnetically Assisted

scholarly journals Novel Compliant Stent with Specific Design for Truncular Venous Malformations: Results of a Porcine Model Study

2019 ◽  
Vol 58 (6) ◽  
pp. e514-e515
Author(s):  
Pierfrancesco Veroux ◽  
Alessia Giaquinta ◽  
Giulia Bernardini ◽  
Carla Virgilio ◽  
Massimiliano Veroux
Keyword(s):  
Porcine Model ◽  
Venous Malformations ◽  
Specific Design ◽  
Model Study

scholarly journals Trend analysis of O3and CO in the period 1980-1996: A three-dimensional model study

2000 ◽  
Vol 105 (D23) ◽  
pp. 28907-28933 ◽  
Author(s):  
Sigrún Karlsdóttir ◽  
Ivar S. A. Isaksen ◽  
Gunnar Myhre ◽  
Terje K. Berntsen
Keyword(s):  
Trend Analysis ◽  
Three Dimensional ◽  
Dimensional Model ◽  
Three Dimensional Model ◽  
Model Study

scholarly journals Retrospective accuracy analysis of MRI based lesion size measurement in neuroblastic tumors: which sequence should we choose?

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sebastian Gassenmaier ◽  
Ilias Tsiflikas ◽  
Simon Maennlin ◽  
Cristian Urla ◽  
Steven W. Warmann ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Tumor Size ◽  
Three Dimensional ◽  
Lesion Size ◽  
Three Dimensions ◽  
Neuroblastic Tumor ◽  
Significant Difference ◽  
Dimensional Measurements ◽  
Neuroblastic Tumors ◽  
Mri Measurements

Abstract Background MR imaging of neuroblastic tumors is widely used for assessing the effect of chemotherapy on tumor size. However, there are some concerns that MRI might falsely estimate lesion diameters due to calcification and fibrosis. Therefore, the aim of our study was to compare neuroblastic tumor size based on MRI measurements to histopathology measurements of the resected specimens as standard of reference. Methods Inclusion criteria were diagnosis of a neuroblastic tumor, MR imaging within 100 days to surgery and gross total resection without fragmentation of the tumor between 2008 and 2019. Lesion diameters were measured by two radiologists according to RECIST 1.1 in axial plane in T2w turbo spin echo (TSE), diffusion-weighted imaging (DWI), and in T1w pre- and postcontrast sequences. Furthermore, the largest lesion size in three-dimensions was noted. The largest diameter of histopathology measurements of each specimen was used for comparison with MRI. Results Thirty-seven patients (mean age: 5 ± 4 years) with 38 lesions (neuroblastoma: n = 17; ganglioneuroblastoma: n = 11; ganglioneuroma: n = 10) were included in this retrospective study. There was excellent intra-class correlation coefficient between both readers for all sequences (> 0.9) Tumor dimensions of reader 1 based on axial MRI measurements were significantly smaller with the following median differences (cm): T1w precontrast − 1.4 (interquartile range (IQR): 1.8), T1w postcontrast − 1.0 (IQR: 1.9), T2w TSE: -1.0 (IQR: 1.6), and DWI -1.3 (IQR: 2.2) (p < 0.001 for all sequences). However, the evaluation revealed no significant differences between the three-dimensional measurements and histopathology measurements of the resected specimens regardless of the applied MRI sequence. Conclusions Axial MRI based lesion size measurements are significantly smaller than histopathological measurements. However, there was no significant difference between three-dimensional measurements and histopathology measurements of the resected specimens. T2w TSE and T1w postcontrast images provided the lowest deviation and might consequently be preferred for measurements.

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