DAILY GOAL ASSESSMENT PROTOCOL: AN EFFECTIVE STRATEGY FOR DEEP VENOUS THROMBOSIS (DVT) PROPHYLAXIS

CHEST Journal ◽  
2008 ◽  
Vol 134 (4) ◽  
pp. 58P
Author(s):  
Khursheed Haider ◽  
Faisal Malik ◽  
Ronald Ciubotaru ◽  
Syed S. Ali ◽  
Rahman Mujibur
2017 ◽  
pp. 74-78
Author(s):  
Duc Thao Mai ◽  
Quoc Tuan Dang

Purpose: To determine the rate of Deep Venous Thrombosis (DVT) in intensive care unit (ICU) patients. Effective DVT prophylaxis with low-molecular-weight heparin in ICU patients. Materials and method: Descriptive Study. 120 patients were admitted ICU from June, 2016 to January, 2016. with age > 18 years, APACHE II score> 18 and is expected to lie ≥ 6 days of treatment, and quantitative D-dimer, doppler ultrasound lower limb venous doppler have pressed. Follow up and re-test the Doppler ultrasound scan after 7 days, 14 days, 21 days and end after 1 month. Results: (i) In our study the rate of DVT is 46.7%, which essentially undetectable at the time of admission of patients at 76.8% and 23.2% being in the days following. (ii) 34% of patients are used prophylactic DVT, The incidence of DVT in the group prophylaxis is lower than with no prophylaxis, this is statistically significant with P <0.001. Conclusion: (i) The incidence of DVT in ICU patients in the study 46.7%. (ii) 34% of patients with DVT prophylaxis, DVT prophylaxis is effective with P <0.001. Key words: Incidence, deep vein thrombosis, prevention


Author(s):  
Alisha Singh ◽  
Mary Samuel ◽  
Vijay Sundarsingh ◽  
Pratik Kabra ◽  
Anshu Kumari

Introduction: Deep Venous Thrombosis (DVT) is one of the critical complications which can occur in patients subsequent to surgeries. The patients in Surgical Intensive Care Units (SICU) have increased propensity to have DVT due to prolonged immobilisation, invasive interventions and other risk factors. It is important to prevent DVT as this can lead to catastrophic Pulmonary Embolism (PE) and balance the risk of haemorrhages due to pharmacotherapy. Aim: To observe the DVT prophylaxis methods and to compare the incidence of DVT in the different methods used in SICU. Materials and Methods: The present study was a prospective cross-sectional study in which 62 patients, aged between 18-70 years admitted in SICU for more than or equal to two days, were included in the study. Patients on drugs affecting cardiovascular system and having significant co-morbidities and coagulation abnormalities, that can impact the occurrence of DVT, were excluded. All patients were followed-up till 28 days or ICU discharge, whichever was later. Patients were evaluated for type of prophylaxis for DVT that included any of mechanical interventions {such as stockings or Sequential Compression Devices (SCD)} or pharmacotherapy (Low molecular weight heparin or Unfractionated heparin) or a combination of both. Statistical analysis was carried out using Student’s t-test and Chi-square test. Results: Thirty (48.39%) patients were given both mechanical and pharmacotherapy, 12 (19.35%) had used only mechanical interventions and 20 (32.26%) had used pharmacotherapy alone for DVT prophylaxis. The overall incidence of DVT was 3.33% (one patient) for patients receiving both mechanical and pharmacotherapy whereas it was 10% (two) for those receiving pharmacotherapy alone and 16.67% (two) for those using mechanical intervention alone. Incidence of haemorrhage was highest in pharmacotherapy alone {three patients (15%)}. The overall dose of drugs used as pharmacotherapy was the least in those receiving dual interventions compared to that of patients receiving pharmacotherapy alone. Conclusion: Pharmacotherapy and pressure stockings together are an ideal therapy for DVT prophylaxis.


2019 ◽  
Vol 7 (12) ◽  
pp. 232596711988848
Author(s):  
Ian D. Engler ◽  
Jack T. Bragg ◽  
Suzanne L. Miller

Background: Rates of deep venous thrombosis (DVT) have been studied for most common orthopaedic injuries. However, rates and risk factors have not been published for proximal hamstring injuries. Purpose: To determine the incidence of symptomatic DVT associated with proximal hamstring rupture and associations with prophylactic anticoagulation. Study Design: Case series; Level of evidence, 4. Methods: Inclusion criteria included all complete and, in a separate cohort, partial proximal hamstring ruptures treated by the senior author from 2007 through 2018 with at least 8 weeks of follow-up. Tendinopathy without tear was excluded. No DVT screening was performed. Charts of patients with symptomatic DVT were reviewed for the treatment method, the presence of imaging-confirmed DVT or pulmonary embolism, and risk factors for DVT. No patients received postinjury DVT prophylaxis. Surgical patients were routinely instructed to take aspirin (325 mg bid) or apixaban (2.5 mg bid) for 4 weeks. Patients with risk factors for DVT received enoxaparin (40 mg daily) for 2 weeks followed by aspirin (325 mg bid) for 2 weeks. Results: A total of 144 complete proximal hamstring ruptures were included: 132 treated operatively and 12 treated nonoperatively. There were 10 DVTs associated with the injury, for an overall rate of 6.9%. Five of the DVTs were diagnosed preoperatively in patients who had not received DVT prophylaxis; the other 5 were diagnosed postoperatively in patients on DVT prophylaxis. Six of the 10 DVTs had identifiable risk factors. All patients with postoperatively diagnosed DVTs were on prophylactic aspirin or enoxaparin. In the partial proximal hamstring rupture cohort of 114 ruptures, there were no DVTs. Conclusion: There is a high incidence of DVT associated with complete proximal hamstring ruptures (6.9%) despite many patients receiving DVT prophylaxis. This is substantially higher than that in other lower extremity injuries. Clinicians should have a high index of suspicion for DVT after these injuries, and postinjury DVT prophylaxis may be warranted.


2021 ◽  
Vol 8 (5) ◽  
pp. 1625
Author(s):  
Manisha Aggarwal ◽  
Janitta Kundaikar ◽  
Dinesh Manchikanti ◽  
Shaji Thomas ◽  
Ashish Arsia ◽  
...  

Cancer being a prothrombotic state, frequently has vascular complications, venous thrombosis, embolism, recurrent venous thromboembolism and a high frequency of anticoagulant failure. We present a rare case of anticoagulant-resistant, progressive, multifocal venous thrombosis and gangrene in all four limbs in a patient with carcinoma gallbladder. A 49 year old lady with locally advanced gallbladder cancer who had been on routine perioperative deep venous thrombosis (DVT) prophylaxis presented two months later with deep venous thrombosis of both lower limbs progressing to venous gangrene of both feet, despite being on anticoagulation. 7 days later, she presented with venous gangrene of both hands. Shortly thereafter, she developed right facial paralysis due to thrombus in the segmental branch of the left MCA despite being on anticoagulation. The hypercoagulable state in cancer involves procoagulant molecules produced by tumor cells, suppression of fibrinolytic activity and platelet activation and is contributed by interactions between the coagulation cascade, complement pathway and immune system. Upto 15% of patients with cancer will develop DVT following surgery, despite standard DVT prophylaxis. Extended DVT prophylaxis should be considered in high-risk patients. Patients with metastases should continue with indefinite anticoagulant therapy after a thrombotic event. In patients without metastasis, anticoagulant treatment is recommended for as long as the cancer is active and while the patient is receiving antitumor therapy. This rare case has been presented to highlight the hypercoagulable state of cancer, the importance of long-term anticoagulation in advanced and metastatic cancers and the high rate of anticoagulation failure associated with unfavourable tumor biology.


2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
Jerrin C. Mathew ◽  
Unnikrishnan Pillai ◽  
Alexander Lacasse

The risk of venous thromboembolism (VTE) in patients with Neuroleptic malignant syndrome (NMS) and those on antipsychotic medications is well established. We present here a case whereby the patient had NMS and developed extensive deep venous thrombosis (DVT) despite being on standard DVT Prophylaxis. Our case illustrates that empiric intravenous heparin for the initial few days after the onset of NMS may be considered in those with high risk of VTE, as in such patients standard DVT prophylaxis may not be sufficient. To standardize as to which patients with NMS would be at the highest risk of VTE while on standard DVT prophylaxis, the role of a standardized scoring system and a double-blind randomized trial in the future would probably be beneficial.


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