scholarly journals Non-Fluoridated Remineralising Agents - A Review of Literature

2021 ◽  
Vol 10 (9) ◽  
pp. 638-644
Author(s):  
Akriti Batra ◽  
Vabitha Shetty

Dental caries is not merely a continuous and one-way process of demineralisation of the mineral phase, but repeated episodes of demineralisations and remineralisation. The remineralisation process is a natural repair mechanism to restore the minerals again, in ionic forms, to the hydroxyapatite (HAP) crystal lattice. It occurs under nearneutral physiological pH conditions whereby calcium and phosphate mineral ions are redeposited within the caries lesion from saliva and plaque fluid resulting in the formation of newer HAP crystals, which are larger and more resistant to acid dissolution. An insight into the caries process’s multifactorial aetiopathogenesis has resulted in a paradigm shift towards minimally invasive dentistry. This era of personalised care using the medical model for caries management assimilates the signs of examining, diagnosing, intercepting, and managing dental caries at a microscopic level. Fluoride mediated salivary remineralisation system is considered the cornerstone of non-invasive approach for managing non-cavitated carious lesions. However, the effect of fluoride was found to be limited to the outer surface of the tooth, and it was observed that fluoride does not influence the modifiable factors in dental caries such as the biofilm. Hence, fluoride does not reduce the cariogenic challenge especially for high-risk individuals. Due to this gap in the conventional fluoride therapies, non-fluoridated remineralising systems have emerged, which interact with the tooth by delivering calcium and phosphorous ions, modifying the biofilm and neutralising the organic acids. This review re-examines the philosophy behind non-fluoridated remineralisation, their mode of action, availability in the market and evidence-based studies of the most promising advancements in remineralisation approaches. KEY WORDS Caries, Minimally Invasive Dentistry, Remineralisation, Non-Fluoridated Remineralising Systems

2017 ◽  
Vol 34 (3) ◽  
pp. 123-128
Author(s):  
Natalia Elson ◽  
Irene Brandes

The preservation of healthy human body and function for every patient should be the goal of all health practitioners. Dentistry is not an exception to this philosophy. In past few decades, the improvements of scientific method and technology has led to a better understanding of oral microflora and dental materials resulted in the shifting of caries management method from G. V. Black’s “extension for prevention” to the modern “minimally invasive” approach in dentistry. The minimally invasive approach to dental caries establishes a proper doctor-patient relationship, thus empowering and educating the patient to take responsibility for their own dental health. The proper sequence of caries management should be the introduction of preventive strategies such as oral hygiene instructions, reminialization regiments, and risk assessments followed by minimal surgical interventions. Using the laser technology in the aspect of surgical intervention has many clinical advantages. Some of the clinical benefits include its selectivity for carious tissue, reduction of needs for local anesthesia, decontamination effect of preparation surfaces, minimal thermal stimulus to pulp chamber, increase in surface adhesion for composite materials, and other soft tissue applications. The combination of caries prevention program, disease control, risk assessment, and laser technology application on the surgical intervention significantly reduces the long-term restorative needs and thus preserves more healthy natural tooth structures, which complement the concept of minimally invasive dentistry. In cosmetic surgery, the same rules apply. The same laser types are used as well.


BMC Biology ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Alexander Ziegler ◽  
Christina Sagorny

Abstract Background In zoology, species descriptions conventionally rely on invasive morphological techniques, frequently leading to damage of the specimens and thus only a partial understanding of their structural complexity. More recently, non-destructive imaging techniques have successfully been used to describe smaller fauna, but this approach has so far not been applied to identify or describe larger animal species. Here, we present a combination of entirely non-invasive as well as minimally invasive methods that permit taxonomic descriptions of large zoological specimens in a more comprehensive manner. Results Using the single available representative of an allegedly novel species of deep-sea cephalopod (Mollusca: Cephalopoda), digital photography, standardized external measurements, high-field magnetic resonance imaging, micro-computed tomography, and DNA barcoding were combined to gather all morphological and molecular characters relevant for a full species description. The results show that this specimen belongs to the cirrate octopod (Octopoda: Cirrata) genus Grimpoteuthis Robson, 1932. Based on the number of suckers, position of web nodules, cirrus length, presence of a radula, and various shell characters, the specimen is designated as the holotype of a new species of dumbo octopus, G. imperator sp. nov. The digital nature of the acquired data permits a seamless online deposition of raw as well as derived morphological and molecular datasets in publicly accessible repositories. Conclusions Using high-resolution, non-invasive imaging systems intended for the analysis of larger biological objects, all external as well as internal morphological character states relevant for the identification of a new megafaunal species were obtained. Potentially harmful effects on this unique deep-sea cephalopod specimen were avoided by scanning the fixed animal without admixture of a contrast agent. Additional support for the taxonomic placement of the new dumbo octopus species was obtained through DNA barcoding, further underlining the importance of combining morphological and molecular datasets for a holistic description of zoological specimens.


2018 ◽  
Vol 53 (3) ◽  
pp. 284-295 ◽  
Author(s):  
Nebu Philip

The principles of minimally invasive dentistry clearly dictate the need for clinically effective measures to remineralize early enamel caries lesions. While fluoride-mediated remineralization is the cornerstone of current caries management philosophies, a number of new remineralization strategies have been commercialized or are under development that claim to promote deeper remineralization of lesions, reduce the potential risks associated with high-fluoride oral care products, and facilitate caries control over a lifetime. These non-fluoride remineralizing systems can be broadly categorized into biomimetic enamel regenerative technologies and the approaches that repair caries lesions by enhancing fluoride efficacy. This paper discusses the rationale for non-fluoride remineralization and the mechanism of action, challenges, and evidence behind some of the most promising advances in enamel remineralization therapies.


2011 ◽  
Vol 05 (02) ◽  
pp. 229-236 ◽  
Author(s):  
Boniek Castillo Dutra Borges ◽  
Juliane de Souza Borges ◽  
Larissa Sgarbosa Napoleao de Araujo ◽  
Claudia Tavares Machado ◽  
Alex Jose Souza dos Santos ◽  
...  

ABSTRACTDental caries on tooth surfaces is still a problem in many industrialized countries. For many years, dentistry was influenced by a mechanical approach characterized by the use of high-speed rotary cutting instruments, and dentists predominantly used surgical methods to address caries. This included radical removal of diseased portions of the tooth, along with material-driven geometric extensions to areas that were assumed to be caries-resistant. This concept of extension for prevention was introduced by G. V. Black and influenced dentists for more than 120 years. Recently, a new paradigm of operative conservatism, sometimes referred to as “minimally invasive dentistry,” has gained popularity. This paradigm is designed to promote maximum preservation of healthy dental structures over a lifetime. The aim of this review is to discuss the efficacy of current nonsurgical treatments for non-cavitated caries lesions in permanent teeth. Based on results obtained from clinical trials, this review evaluates treatments such as consumption of CPP-ACP added gums, resin infiltration and fissure sealing. Although in a few cases an invasive approach is needed to arrest caries progression, the non-surgical approach generally provides potential benefits that include conserving structure by delaying intervention or minimizing the operative procedure. All current non-invasive methods are effective in treating non-cavitated caries lesions. The adoption of non-invasive approaches in the management of these lesions can preserve dental tissues, thus increasing tooth longevity. (Eur J Dent 2011;5:229-236)


2021 ◽  
Vol 10 (5) ◽  
pp. 700-705
Author(s):  
Angélica Feltrin Dos Santos ◽  
Tainara Tonon Castelluccio ◽  
Gerson Aparecido Foratori-Junior ◽  
Daniela Rios ◽  
Linda Wang ◽  
...  

The concept of minimally invasive dentistry certainly promoted significant changes towards more conservative dental caries management, which allows for quality information regarding the diagnosis, prognosis, and clinical management of dental caries even regarding the maintenance of restorative procedures. This case report aimed to highlight the relevance and feasibility of a streamlined caries disease management based on caries-risk determination and minimal invasive concepts associated with bioactive materials. A 13-year-old female patient sought dental care. Clinically, active white spot lesion on the occlusal surface of right upper first premolar coming from the fissures was noteworthy under moist condition. Bitewing radiography confirmed an interproximal carious lesion involving dentin. The cavity preparation was performed as more conservative as possible, removing the carious tissue selectively and treated with bioactive materials. After 12-month follow-up, successful performance of the restoration was seen while the patient caries-risk condition seems to be under control. This clinical case demonstrates that a correct diagnosis associated with smart materials and appropriate restorative procedures can offer effective and conservative results. Evidence-based treatment benefits patient avoiding unnecessary dental compromising and the maintenance of oral health.


Dental Update ◽  
2021 ◽  
Vol 48 (2) ◽  
pp. 145-147
Author(s):  
Tal Ziv

Interdental space between anterior teeth is an aesthetic and a phonetic problem. While various treatment options are available, patients often have concerns regarding treatment invasiveness, duration of treatments, costs and long-term prognosis. This case report describes a step-by-step smile makeover with direct composite restorations in maxillary incisors and canines with interdental spaces, tooth size discrepancy and altered passive eruption. CPD/Clinical Relevance: Minimally invasive dentistry is an integral component of contemporary clinical practice With recent advances in innovative materials and improved clinical technique, attaining aesthetic results with a minimally invasive approach is highly achievable.


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