scholarly journals Mental Nerve Schwannoma - A Rare Cause of Lower Jaw Swelling

2021 ◽  
Vol 10 (22) ◽  
pp. 1735-1738
Author(s):  
Geetha Rajendran ◽  
Karthik Ragupathy ◽  
Sanjay Pasupathy ◽  
Ganesh Ramakrishnan ◽  
Kiruthika Shriranjani
Keyword(s):  
Head And Neck ◽  
Schwann Cells ◽  
Peripheral Nerves ◽  
Cranial Nerves ◽  
Neck Region ◽  
Periapical Lesion ◽  
Lower Cranial Nerve ◽  
Head And Neck Region ◽  
Lower Jaw ◽  
Slow Growing

Schwannomas are relatively rare benign neoplasms of neurogenic origin from the neural sheath of peripheral nerves occurring more commonly in the head and neck. Mandibular bone is the commonest site of occurrence of these nerve lesions. Radiographically, intraosseous schwannoma of mandible is very difficult to differentiate from other bony pathologies such as neurofibroma, ameloblastoma, fibrous dysplasia, myxoma, central giant cell lesion, or periapical lesion, so it should be included in the differential diagnosis of lower jaw swelling. Schwannoma as a pathologic entity was first reported in 1910 by Verocay. Schwannoma (also known as neurinoma, neurolemmoma, neurilemmoma, perineural fibroblastoma, and peripheral nerve sheath tumour) is a rare, slowgrowing, benign neurogenic neoplasm that originated from Schwann cells. Schwann cells cover myelinated sheath of nerve fibres.1 These intraosseous schwannomas account for not more than 1 % of the central neoplasms. More than one third of all schwannomas are found in the head and neck region. 2 Most of these originate from the lower cranial nerve and sympathetic nervous system. Schwannomas from the upper cranial nerves such as trigeminal nerve and its branches are less common. Other commonly reported sites include the vertebra, clavicle, ribs, sacrum, humerus, ulna radius, etc. This painless slow-growing neoplasm may develop at any age.

scholarly journals Asymptomatic nodule on face: Dermoscopic and histopathological clue for diagnosis

2020 ◽  
Vol 17 (1) ◽  
pp. 63-65
Author(s):  
Anisha Joshi ◽  
Deeptara Pathak Thapa
Keyword(s):  
Head And Neck ◽  
Peripheral Nerves ◽  
Neck Region ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Complete Excision ◽  
Head And Neck Region ◽  
The Common ◽  
Slow Growing ◽  
Rare Diagnosis

Schwannomas/ neurilemmomas are benign tumors of nerve sheath arising from Schwann cells that form myelin sheath around peripheral nerves. They are usually solitary, slow growing and encapsulated lesions. Head and neck are the common sites. We report a case of a 38 years old Nepalese female who had presented with a solitary asymptomatic, slow growing nodule on the left side of the chin for the last three years. Dermoscopy of the lesion revealed arborizing vessels with brownish pigmentation overlying a whitish to pinkish background. Complete excision of the lesion was performed. Histopathological evaluation of the lesion revealed schwannoma. Though schwannomas are a rare diagnosis, they should be considered as a differential diagnosis of any unilateral, asymptomatic, slow growing nodule in the head and neck region. Dermoscopy is a useful tool which helps to differentiate schwannoma from other lesions. Histopathology is the gold standard for diagnosis and the treatment of choice is surgical excision.  

scholarly journals A rare clinical case: schwannoma of tongue

2019 ◽  
Vol 5 (3) ◽  
pp. 789
Author(s):  
Chandra Veer Singh ◽  
Sheetal Radia ◽  
Saalim Sheikh ◽  
Vijay Haribhakti
Keyword(s):  
Head And Neck ◽  
Rare Case ◽  
Neck Region ◽  
Surgical Excision ◽  
Imaging Studies ◽  
Head And Neck Tumours ◽  
Head And Neck Region ◽  
Complete Surgical Excision ◽  
Slow Growing ◽  
Rule Out

<p class="abstract">Schwannoma are slow growing tumours, which can arise from any peripheral nerve. 10% of schwannomas that occur in the head and neck region mostly originate from the vagus or sympathetic nervous system. Extracranial schwannomas in the head and neck region are rare neoplasm. Intraoral schwannoma are only 1% of the all head and neck tumours. Diagnosis is established by imaging studies such as magnetic resonance imaging or computed tomography, while FNAC is used to rule out other conditions. We report a rare case of lingual schwannomas generally present as a painless lump schwannoma of the tongue in a 27-year-old male complaining of asymptomatic swelling over a posterolateral surface of the tongue, treated by complete surgical excision. The diagnosis was established on the basis of clinical, histopathological, and immunohistochemical examination. We report a rare case of schwannoma over the posterolateral surface of tongue. Prognosis is good for the patient when this condition is correctly diagnosed as the condition rarely recurs after complete resection.</p>

scholarly journals Rare extracranial localizations of the head and neck schwannomas

2010 ◽  
Vol 67 (7) ◽  
pp. 596-599
Author(s):  
Milan Jovanovic ◽  
Ljiljana Cvorovic ◽  
Rastislav Poljovka ◽  
Aleksandar Oroz ◽  
Ljubomir Pavicevic
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Soft Tissue Tumors ◽  
Autonomic Nerves ◽  
Head And Neck Region ◽  
Delay In Diagnosis ◽  
Benign Soft Tissue Tumors ◽  
Indispensable Tool ◽  
Slow Growing ◽  
Nerve Of Origin

Introduction. Schwannomas are tumors of neurogenic origin, that arise from Schwann cells which surround peripheral, cranial and autonomic nerves. Schwannomas account for only 5% of all benign soft tissue tumors, and 25-45% of extracranial schwannomas are present in the head and neck region. They are usually classified according to the nerve of origin and the site within the head and neck. Case report. We presented extremely rare extracranial localizations of schwannomas and discussed about diagnosis and management of these tumors. Conclusion. Schwannomas are slow-growing tumors and late symptoms appearance may cause a delay in diagnosis and treatment of patients with these tumors. An appropriate diagnostic protocol is indispensable tool in performing a differential diagnosis of malignant from benign lesions. Choice of surgical approach depends on schwannomas localization.

Schwannoma of the palatine tonsil

2005 ◽  
Vol 119 (7) ◽  
pp. 570-572 ◽  
Author(s):  
H T Anil ◽  
B V Chandre Gowda ◽  
S Lakshmi ◽  
S R Niveditha
Keyword(s):  
Head And Neck ◽  
Schwann Cells ◽  
Neck Region ◽  
Benign Tumour ◽  
Palatine Tonsil ◽  
Autonomic Nerves ◽  
Head And Neck Region ◽  
The Third ◽  
Acoustic Nerve ◽  
Neural Sheath

Schwannoma is a solitary, benign tumour arising from the neural sheath Schwann cells of the peripheral, cranial or autonomic nerves. In the head and neck region, it occurs most commonly in association with the acoustic nerve within the skull and is rarely found in oral structures. When it is found in oral structures, the tongue is reported to be the favoured site. Schwannoma of the tonsil is extremely rare, with only two cases reported in the literature. We report what is, to our knowledge, the third case of schwannoma of the tonsil, diagnosed by histopathology.

Intramuscular Hemangioma of the sternocleidomastoid muscle: A Rare Unusual Neck Mass

2020 ◽  
Vol 13 (1) ◽  
pp. 78-82
Author(s):  
Brihaspati Sigdel ◽  
Rajesh Maharjhan ◽  
Tulika Dubey ◽  
Bhima Neupane
Keyword(s):  
Head And Neck ◽  
Rare Case ◽  
Neck Region ◽  
Neck Mass ◽  
Sternocleidomastoid Muscle ◽  
Benign Tumors ◽  
Head And Neck Region ◽  
Intramuscular Hemangioma ◽  
Slow Growing ◽  
Extensive Involvement

Hemangiomas of the head and neck region comprise about 60 to 70% of all benign tumors. Intramuscular hemangioma is a rare, slow-growing, angiomatous tumor. We report a rare case of an Intramuscular Hemangioma of Right sternocleidomastoid muscle in a six years old girl presenting for four years and with extensive involvement necessitating excision. Microscopic excision reduces the risk of recurrence.

Submandibular neurilemmoma; a diagnostic dilemma

2004 ◽  
Vol 118 (2) ◽  
pp. 156-158 ◽  
Author(s):  
Robert Almeyda ◽  
Prasad Kothari ◽  
Ha Chau ◽  
Vincent Cumberworth
Keyword(s):  
Head And Neck ◽  
Neck Region ◽  
Signs And Symptoms ◽  
Benign Neoplasms ◽  
Diagnostic Dilemma ◽  
Head And Neck Region ◽  
Neurological Signs ◽  
Nerve Sheath ◽  
Diagnostic Difficulties ◽  
Slow Growing

Neurilemmomas are slow growing, benign neoplasms of neural crest Schwann cell origin. They arise from any peripheral, spinal or cranial nerve except the olfactory and optic. Presentation is usually asymptomatic but focal neurological signs and symptoms may be associated with nerve compression. With approximately one third of all documented cases presenting in the head and neck region, we report a case of a submandibular neurilemmoma misdiagnosed pre-operatively. The diagnostic difficulties are discussed and the current literature reviewed. Thiscase highlights the importance of inclusion of nerve sheath tumours in differential diagnoses of soft tissue lesions in the head and neck.

Palatal Schwannoma: A Rare Case Report

2016 ◽  
Vol 8 (1) ◽  
pp. 29-31
Author(s):  
Nikhil Arora ◽  
PS Shahul Hameed
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Schwann Cells ◽  
Rare Case ◽  
Benign Tumor ◽  
Neck Region ◽  
Head And Neck Region ◽  
Nerve Sheath ◽  
Rare Case Report ◽  
Slow Growing

ABSTRACT Schwannoma is a benign tumor that originates from perineural Schwann cells of nerve sheath. They are solitary, wellencapsulated, slow-growing adjacent to the parental nerve but extrinsic to the nerve fascicles. Approximately 25 to 45% of all schwannomas are seen in the head and neck region and are found rarely in the oral cavity. Most of the intraoral schwannomas are located in the tongue. Palatal schwannoma is very rare as till date and only 16 cases have been reported; one such rare case we came across is reported here. How to cite this article Hameed PSS, Arora N, Malhotra V. Palatal Schwannoma: A Rare Case Report. Int J Otorhinolaryngol Clin 2016;8(1):29-31.

scholarly journals Schwannomas in the head and neck: retrospective analysis of 21 patients and review of the literature

2007 ◽  
Vol 125 (4) ◽  
pp. 220-222 ◽  
Author(s):  
Erwin Langner ◽  
André Del Negro ◽  
Hugo Kenzo Akashi ◽  
Priscila Pereira Costa Araújo ◽  
Alfio José Tincani ◽  
...  
Keyword(s):  
Head And Neck ◽  
Schwann Cells ◽  
Neck Region ◽  
Diagnostic Methods ◽  
Von Recklinghausen’S Disease ◽  
Von Recklinghausen's Disease ◽  
Head And Neck Region ◽  
Tumor Enucleation ◽  
Recklinghausen's Disease ◽  
Recklinghausen’S Disease

CONTEXT AND OBJECTIVE: Schwannomas are benign neoplasms of the peripheral nerves originating in the Schwann cells. According to their cellularity, they can be subdivided into Antoni A or Antoni B types. They are rare and usually solitary, with clearly delimited capsules. They occur in the head and neck region in only 25% of the cases, and may be associated with Von Recklinghausen's disease. The present study retrospectively analyzed some data on this disease in the head and neck region and reviewed the literature on the subject. DESIGN AND SETTING: Retrospective study at Head and Neck Service, Universidade Estadual de Campinas. METHODS: Data on 21 patients between 1980 and 2003 were reviewed. The sites of cervical schwannomas and the intraoperative, histopathological and postoperative clinical status of these cases were studied. Diagnostic methods, type of surgery and association with neurofibromatosis were evaluated. RESULTS: The patients' ages ranged from 16 to 72 years. Four patients had a positive past history of type I neurofibromatosis or Von Recklinghausen's disease. The nerves affected included the brachial and cervical plexuses, vagus nerve, sympathetic chain and lingual or recurrent laryngeal nerve. The nerve of origin was not identified in six cases. Tumor enucleation was performed in 16 patients; the other five required more extensive surgery. CONCLUSION: Schwannomas and neurofibromas both derive from Schwann cells, but are different entities. They are solitary lesions, except in Von Recklinghausen's disease. They are generally benign, and rarely recur. The recommended surgical treatment is tumor enucleation.

scholarly journals Schwannoma Located in Nasopharyngeal Region

2016 ◽  
Vol 2016 ◽  
pp. 1-3
Author(s):  
Fadlullah Aksoy ◽  
Alper Yenigun ◽  
Erol Senturk ◽  
Orhan Ozturan
Keyword(s):  
Peripheral Nerves ◽  
Histopathological Examination ◽  
Neck Region ◽  
Case Presentation ◽  
Head And Neck Region ◽  
Nerve Sheath ◽  
Swallowing Difficulties ◽  
First Time ◽  
Slow Growing

Schwannoma is a tumor which has neuroectoderm origins, is hard, well-circumscribed, encapsulated, and slow growing benign cranial tumor, and may autonomously grow out of the nerve sheath of peripheral nerves. It is mostly seen in the head and neck region. In the paranasal sinus and nose areas, it is seen at a rate of 4%. The diagnosis is mostly made after histopathological examination. In this paper, a Schwannoma case observed in the nasopharyngeal region was presented in a 20-year-old female who had complaints of sleeping with open mouth, snoring, foreign body feeling in throat, and swallowing difficulties. The tumor was extracted via transoral approach. No recurrence was observed during follow-up over the next year. This case presentation is presented for the first time in the literature in English.

Molecular genetics of paragangliomas of the skull base and head and neck region: implications for medical and surgical management

2014 ◽  
Vol 120 (2) ◽  
pp. 321-330 ◽  
Author(s):  
Ibrahim Hussain ◽  
Qasim Husain ◽  
Soly Baredes ◽  
Jean Anderson Eloy ◽  
Robert W. Jyung ◽  
...  
Keyword(s):  
Head And Neck ◽  
Skull Base ◽  
Molecular Genetics ◽  
Cranial Nerves ◽  
Neck Region ◽  
Mass Effect ◽  
Head And Neck Region ◽  
Carotid Bodies ◽  
Oncogenic Pathways ◽  
Succinate Dehydrogenase Complex

Paragangliomas are rare, slow-growing tumors that frequently arise in the head and neck, with the carotid bodies and temporal bone of the skull base being the most common sites. These neoplasms are histologically similar to pheochromocytomas that form in the adrenal medulla and are divided into sympathetic and parasympathetic subtypes based on functionality. Skull base and head and neck region paragangliomas (SHN-PGs) are almost always derived from parasympathetic tissue and rarely secrete catecholamines. However, they can cause significant morbidity by mass effect on various cranial nerves and major blood vessels. While surgery for SHN-PG can be curative, postoperative deficits and recurrences make these lesions challenging to manage. Multiple familial syndromes predisposing individuals to development of paragangliomas have been identified, all involving mutations in the succinate dehydrogenase complex of mitochondria. Mutations in this enzyme lead to a state of “pseudohypoxia” that upregulates various angiogenic, survival, and proliferation factors. Moreover, familial paraganglioma syndromes are among the rare inherited diseases in which genomic imprinting occurs. Recent advances in gene arrays and transcriptome/exome sequencing have identified an alternate mutation in sporadic SHN-PG, which regulates proto-oncogenic pathways independent of pseudohypoxia-induced factors. Collectively these findings demonstrate that paragangliomas of the skull base and head and neck region have a distinct genetic signature from sympathetic-based paragangliomas occurring below the neck, such as pheochromocytomas. Paragangliomas serve as a unique model of primarily surgically treated neoplasms whose future will be altered by the elucidation of their genomic complexities. In this review, the authors present an analysis of the molecular genetics of SHN-PG and provide future directions in patient care and the development of novel therapies.

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