Portal Vein Diameter in Patients with Liver Cirrhosis and Hepatic Encephalopathy

Background: The aim of the study was to determine the correlation of oesophageal varices (OV) with portal vein diameter and the platelet count to splenic diameter ratio and their comparative evaluation in patients of liver cirrhosis.Methods:The present study consisted of 50 patients diagnosed with liver cirrhosis. Necessary investigations were performed in all the patients including Upper gastrointestinal (GI) endoscopy. Platelet count/spleen diameter ratio, spleen diameter and portal vein diameter were calculated for all patients and the presence and grading of OV was then comparatively evaluated. The results were systematically recorded and statistically analysed.Results: The mean age of patients was 49.82±10.23 years. 78% of patients presented with OV. The portal vein diameter, platelet count, spleen diameter and platelet count/spleen diameter ratio were significantly increased in patients with OV than those without OV (p<0.0001). Highly significant positive correlation between portal vein diameter, spleen diameter and grading of OV was seen. Platelet count/spleen diameter ratio and platelet count was significantly decreased as the grade of OV increased in the patients. There was statistically, a highly significant negative correlation between them.Conclusions: The non-invasive parameters used to detect presence of OV in liver cirrhosis were portal vein diameter and platelet count/spleen diameter ratio. Though, both seemed to be effective in predicting OV, platelet count/spleen diameter ratio proved to be slightly more significant when compared to the other.

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Bright basal ganglia in T1-weighted magnetic resonance images are frequent in patients with portal vein thrombosis without liver cirrhosis and not suggestive of hepatic encephalopathy

Journal of Hepatology ◽

10.1016/s0168-8278(98)80063-9 ◽

1998 ◽

Vol 29 (3) ◽

pp. 443-449 ◽

Cited By ~ 33

Author(s):

Wilhelm Nolte ◽

Jens Wiltfang ◽

Christian G. Schindler ◽

Knut Unterberg ◽

Michael Finkenstaedt ◽

...

Keyword(s):

Liver Cirrhosis ◽

Hepatic Encephalopathy ◽

Basal Ganglia ◽

Magnetic Resonance ◽

Portal Vein ◽

Portal Vein Thrombosis ◽

Magnetic Resonance Images ◽

Vein Thrombosis

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Relationships between Splenorenal Shunt/Portal Vein Diameter Ratio and Systemic Hemodynamics in Patients with Liver Cirrhosis

Digestion ◽

10.1159/000357494 ◽

2014 ◽

Vol 89 (2) ◽

pp. 133-138 ◽

Cited By ~ 4

Author(s):

Fumio Chikamori ◽

Hiroshi Okamoto ◽

Nobutoshi Kuniyoshi

Keyword(s):

Liver Cirrhosis ◽

Portal Vein ◽

Diameter Ratio ◽

Systemic Hemodynamics ◽

Splenorenal Shunt ◽

Vein Diameter

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Prevalence of Gall Stones in Liver Cirrhosis

Journal of Nepal Medical Association ◽

10.31729/jnma.2745 ◽

2015 ◽

Vol 53 (200) ◽

pp. 275-279

Author(s):

Sudhamshu K.C. ◽

Dilip Sharma ◽

Sandip Khadka ◽

Niyanta Karki ◽

Bikash Jaishi ◽

...

Keyword(s):

Risk Factors ◽

Liver Cirrhosis ◽

Portal Vein ◽

Gallstone Disease ◽

Gallstone Formation ◽

Female Ratio ◽

Gall Stones ◽

Vein Diameter ◽

Severity Of The Disease ◽

Male To Female

Introduction: Increased incidence and prevalence of gallstones in liver cirrhosis has already been reported by many studies. This study aimed to investigate the prevalence of gallstone disease in Nepali patients with liver cirrhosis and to identify risk factors for gallstone formation. Methods: Consecutive patients of liver cirrhosis presenting to liver clinic from January, 2010 to December, 2012 were evaluated for GS by ultrasonography at their first visit. Liver cirrhosis was diagnosed on the basis of clinical features, laboratory parameters, ultrasonography, and/or histopathology. Results: Two hundred and twenty four LC patients were studied. Male to female ratio was 2.3:1. Alcohol was the major etiological factor for LC followed by hepatitis B, alone or in conjunction with alcohol. Seventy-four patients (33%) were found to have GS. Incidence of GS was more in advance stage of cirrhosis. There was no significant correlation between formation of GS and etiology of LC, except for the HCV related liver cirrhosis, in which it was present in 39% of the patients. More the advance disease,more was the incidence as 57% of Child-C patients had GS. Portal vein diameter was also associated with GS formation. When portal vein diameter was more than 13 mm, there was more GS formation. Conclusions: One third of the patients of LC showed GS at the presentation. Patients with HCV related cirrhosis are more prone to develop GS than other. Severity of the disease and portal vein diameter was found to be associated with GS formation. Keywords: gallstones; liver cirrhosis; ultrasonography.

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Role of Ultrasonography in Predicting Gastro-oesophageal Varices in Patients with Liver Cirrhosis

Journal of College of Medical Sciences-Nepal ◽

10.3126/jcmsn.v17i1.33325 ◽

2021 ◽

Vol 17 (1) ◽

pp. 10-15

Author(s):

Merina Gyawali ◽

Ramesh Raj Acharya

Keyword(s):

Liver Cirrhosis ◽

Portal Vein ◽

Portal System ◽

Oesophageal Varices ◽

Spleen Size ◽

Cross Sectional ◽

Non Invasive ◽

The Social ◽

Vein Diameter ◽

Splenic Size

IntroductionUpper Gastrointestinal endoscopy is considered the best screening tool in detecting gastroesophagealvarices in patients with cirrhosis. Ultrasonography of the abdomen can be used forassessment of liver and portal system. This research was undertaken to demonstrate that theportal vein diameter and splenic size by ultrasonography can be used as a non-invasive predictorof gastro-esophageal varices. MethodsA cross-sectional hospital based study comprising of 290 consecutive patients with liver cirrhosiswere enrolled between November 2019 to November 2020. Clinical profile at admission andsonological splenic size and portal vein diameter were studied in all cirrhotic patients. Patientswere classified into 2 groups: one with presence of varices and second without varices. Data entrywas done in Statistical Packages for the Social Sciences version 20. ResultsThe mean age of subjects was 52±13.26 years with a range of 27 – 82 years of age (M:F=2:1). Thecommonest etiology of cirrhosis was chronic alcohol consumption. The prevalence of varices incirrhotics was 42.8%. Average portal vein diameter of patients without gastro-esophageal variceswas 11.12 ± 1.36 mm, while it was 12.81 ± 1.62 mm in patients with varices (p < 0.001). Averagespleen size in cirrhotics without varices was 12.44 ± 1.32 cm and with varices was 14.32 ± 2.42 cm.This difference was also statistically significant (p < 0.001). ConclusionsMeasurement of portal vein diameter and spleen size by ultrasonography can be recommendedas a non invasive predictor for gastro-oesophageal varices in patients with liver cirrhosis . Keywords: cirrhosis; portal vein diameter; spleen size; ultrasonography; gastro-oesophageal varices

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Increased portal vein diameter is predictive of portal vein thrombosis development in patients with liver cirrhosis

Annals of Translational Medicine ◽

10.21037/atm-20-4912 ◽

2021 ◽

Vol 9 (4) ◽

pp. 289-289

Author(s):

Gang Dong ◽

Xiao-Quan Huang ◽

Yu-Li Zhu ◽

Hong Ding ◽

Feng Li ◽

...

Keyword(s):

Liver Cirrhosis ◽

Portal Vein ◽

Portal Vein Thrombosis ◽

Vein Thrombosis ◽

Vein Diameter

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Non-Invasive Predictors of Gastro-Oesophageal Varices

Journal of Nepal Medical Association ◽

10.31729/jnma.3202 ◽

2017 ◽

Vol 56 (207) ◽

pp. 298-303 ◽

Cited By ~ 2

Author(s):

Subash Bhattarai ◽

Khus Raj Dewan ◽

Gaurav Shrestha ◽

Bhanumati Saikia Patowary

Keyword(s):

Liver Cirrhosis ◽

Portal Hypertension ◽

Portal Vein ◽

Serum Albumin ◽

Oesophageal Varices ◽

Upper Gastrointestinal Endoscopy ◽

Spleen Size ◽

Non Invasive ◽

Vein Diameter ◽

Cirrhosis Of Liver

Introduction: The worldwide accepted tool for screening and monitoring gastro-oesophageal varices in patients with liver cirrhosis is upper gastrointestinal endoscopy. Endoscopy needs clinical expertise and has got its own procedure related complications. Repeated endoscopies may be expensive and patients tend to develop poor compliance. This study was undertaken to establish the role of noninvasive parameters in predicting gastro-esophageal varices. Methods: Two hundred patients with clinical features, laboratory and sonological findings suggestive of cirrhosis of liver and endoscopic evidence of portal hypertension were included in the study. Blood parameters like serum albumin, international normalized ratio (INR), platelets count and ultrasonography assessments of portal vein diameter and spleen size were compared with presence of gastro-oesophageal varices. Results: At cutoff point of 2.55g/dl, serum albumin had high specificity of 99% whereas platelets count <1,44,000/mm3 had 87.9% sensitivity for presence of oesophageal varices. Sensitivities of 92.72% and 94.5% while specificities of 90% and 75% were detected for presence of oesophageal varices when the cutoff values for portal vein diameter and spleen size were 12.25 mm and 13.9 cm respectively. Conclusions: Measurements of serum albumin, platelets count, portal vein diameter and spleen size by ultrasonography can be recommended as a non-invasive predictor for gastro-oesophageal varices in cirrhosis of liver. All these non-invasive parameters could be useful to patients with liver cirrhosis with portal hypertension in predicting presence of varices as well as in long-term clinical monitoring and management. Keywords: cirrhosis of liver; endoscopy; gastro-oesophageal varices; non-invasive predictors.

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