Hepatic Tuberculosis in an Immunocompetent Patient- a Diagnostic Challenge

2016 ◽  
Vol 111 ◽  
pp. S949
Author(s):  
Arif Nawaz ◽  
Khurram Malik ◽  
Aftab Alvi ◽  
Bushra Ali
2021 ◽  
Vol 54 (3) ◽  
pp. 111
Author(s):  
Pranita Mohanty ◽  
Anasuya Lenka ◽  
T Govardhan ◽  
Souvagya Panigrahi

2021 ◽  
Vol 14 (3) ◽  
pp. e236892
Author(s):  
Mark Brahier ◽  
Rhanika Neuda ◽  
William Davis ◽  
Rita Poon

Medical tourism is the pursuit of more affordable surgeries; however, this comes at the risk of suboptimal standards and potential for life-threatening complications. In this case, we describe the diagnostic challenge of cytomegalovirus (CMV) pneumonia in a 40-year-old woman who experienced wound dehiscence and subsequent blood transfusion-transmitted CMV as complications of liposuction in the Dominican Republic. We explore the role of histopathology in the diagnosis of disseminated CMV, discuss the underlying aetiology of CMV pneumonia in this patient and weigh the risks and benefits of initiating antiviral therapy in an immunocompetent patient with CMV disease.


2013 ◽  
Vol 2013 (dec16 1) ◽  
pp. bcr2013010262-bcr2013010262 ◽  
Author(s):  
M. Hanafiah ◽  
S. M. I. Alhabshi ◽  
T. Bag ◽  
S. F. Low

2020 ◽  
Vol 40 (4) ◽  
pp. 346
Author(s):  
Valeria Costa-Barney ◽  
Andrés F. Delgado-Villarreal ◽  
Ana María Leguízamo ◽  
Rómulo Darío Vargas

Intestinal tuberculosis and Crohn's disease are a diagnostic challenge because of the clinical, radiological and endoscopic similarity. The histological and microbiological findings are positive in less than 50%, which delays the correct treatment, putting the patient at risk. We reported a 34-year-old immunocompetent patient with 4 years of malabsorptive diarrhea, weight loss, nocturnal diaphoresis, abdominal pain and an ulcer with stenosis in the jejunum was found; she mpirical antituberculosis treatment with clinical improvement. Later the culture was positive for M. tuberculosis.


2020 ◽  
Vol 13 (5) ◽  
pp. e234491
Author(s):  
Marta Freitas ◽  
Joana Magalhães ◽  
Carla Marinho ◽  
José Cotter

Primary hepatic tuberculosis is a rare clinical entity with non-specific clinical and imaging features that can mimic other liver diseases, representing a diagnostic challenge. We report a case of a 35-year-old man with metabolic syndrome, type 2 diabetes and high alcohol consumption presenting asymptomatic with abnormal liver tests, hepatosplenomegaly and diffuse hepatic steatosis in ultrasound imaging initially suspected to be alcoholic steatohepatitis but later diagnosed as hepatic tuberculosis in the histological specimen. Anti-tuberculosis therapy was started. This clinical case highlights the diagnostic difficulty of hepatic tuberculosis and the importance of not overlooking liver biopsy and to consider it in the differential diagnosis in patients with obvious hepatic injury factors but with atypical clinical presentation.


2021 ◽  
Vol 14 (11) ◽  
pp. e245517
Author(s):  
Alexandra Borges ◽  
Lìgia Ferreira ◽  
Ricardo Pacheco ◽  
Isabel Fonseca

We describe the case of a 32-year-old man from Cape Verde having headache and increasing visual loss. Clinical and radiological investigations disclosed a massive destructive lesion involving the anterior and central skull base, orbit and nasoethmoid region initially interpreted as a malignant small round cell tumour. Surgical biopsies were negative for neoplasm, showing an intense inflammatory infiltrate together with fungus, later characterised as Aspergillus flavus spp. The patient was immunocompetent with no evidence of congenital or acquired immunodeficiencies. Invasive fungal infections in immunocompetent patients are rare and can be a diagnostic challenge. The best diagnostic clues include the patient’s origin from tropical climates, imaging features and the identification of fungal hyphae on pathology specimens. Although a devastating disease in immunocompromised patients, craniocerebral aspergillosis in immunocompetent patients carries a better prognosis. Available literature supports the combined used of ‘conservative’ surgical resection and antifungal therapy as the best treatment option.


Diseases ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 75 ◽  
Author(s):  
Dan Zimelewicz Oberman ◽  
Liliana Patrucco ◽  
Carolina Cuello Oderiz

Cryptococcal meningitis is a life-threatening condition caused by a fungal pathogen, Cryptococcus neoformans, that can infect both immunosuppressed and immunocompetent hosts. It is an important cause of morbidity and mortality in severely immunodeficient patients. However, in an immunocompetent patient it represents a diagnostic challenge, mainly because it is extremely rare, but also because of its nonspecific clinical manifestation. Neurovascular involvement in cryptococcal meningitis is rare and not well known and only few reports have described this association. We describe a cryptococcal meningitis in an immunocompetent patient associated with central nervous system vasculitis.


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Nikolaos Garmpis ◽  
Christos Damaskos ◽  
Anna Garmpi ◽  
Aliki Liakea ◽  
Dimitrios Mantas

Background/Aim. Tuberculosis (TB) is a chronic infectious disease which affects millions. The most affected system is the respiratory. Thus, hepatic TB (HTB) without involvement of other organs is not common. Its clinical manifestations are not specific, and both imaging and histopathological findings are necessary for the diagnosis. The differential diagnosis includes primary and metastatic liver malignancies. Our aim is to describe the rare entity of HTB via a case presentation. Patient and Methods. We report a case of a 50-year-old female with abdominal pain, weight loss, fever, and anorexia. All imaging methods described a liver lesion. She underwent right lobe hepatectomy, and the histological evaluation demonstrated granuloma with central caseous necrosis. Results. Seven months postoperatively, the patient remains fit and healthy. Conclusion. HTB is a rare entity with no specific symptoms, signs, and no laboratory nor imaging findings. It can be managed effectively if diagnosed in time or lead to death if left untreated.


Cureus ◽  
2021 ◽  
Author(s):  
Zorays Moazzam ◽  
Amman Yousaf ◽  
Zahid Iqbal ◽  
Ahmad Tayyab ◽  
Muhammad Hashim Hayat

Sign in / Sign up

Export Citation Format

Share Document