scholarly journals S354 Using FLIP Panometry to Characterize Contractile Response Patterns in Patients With Eosinophilic Esophagitis

2021 ◽  
Vol 116 (1) ◽  
pp. S153-S153
Author(s):  
Christina Shehata ◽  
Dustin Carlson ◽  
NIrmala Gonsalves ◽  
Ikuo Hirano ◽  
Peter J. Kahrilas ◽  
...  
Keyword(s):  
Eosinophilic Esophagitis ◽  
Contractile Response ◽  
Response Patterns

scholarly journals ACTION OF CYTOCHALASIN D ON CELLS OF ESTABLISHED LINES

1974 ◽  
Vol 61 (2) ◽  
pp. 481-500 ◽  
Author(s):  
Armand F. Miranda ◽  
Gabriel C. Godman ◽  
Arline D. Deitch ◽  
Stuart W. Tanenbaum
Keyword(s):  
Contractile Response ◽  
Sugar Transport ◽  
Cytochalasin D ◽  
Response Patterns ◽  
Early Effect ◽  
Mdbk Cells ◽  
Hexose Uptake ◽  
Cytoplasmic Processes ◽  
Indirect Action ◽  
Structural Disruption

HeLa, Vero, L, HEp2, and MDBK cells respond immediately to 0.2–0.5 µg/ml cytochalasin D (CD) with sustained contraction (contracture), loss of microvilli, expression of endoplasmic contents (zeiosis), nuclear protrusion, and extension of cytoplasmic processes. The development of these changes is depicted, and the dose-response patterns in these cell lines are described. MDBK is generally most resistant and HeLa most sensitive to these effects of CD. Cells in G1 are most sensitive to CD; responsiveness decreases progressively during early S and is least in mid S through G2. CD inhibits transport of [14C]deoxyglucose in HeLa by about 45% but has no significant effect on hexose uptake in Vero and MDBK; sugar transport is thus apparently unrelated to any morphologic effect of CD. Although spreading and attachment are impeded, CD does not decrease and may even enhance the adhesiveness of established monolayers. Contraction appears to be a primary early effect of CD, upon which other visible changes follow. It is prevented by some inhibitors of energy metabolism (deoxyglucose and dinitrophenol) and does not occur in glycerinated models without ATP. The possible bases of the contractile response to CD are discussed. Although direct or indirect action of CD on some microfilaments may occur, a generalized structural disruption of contractile filaments by CD is considered unlikely.

Mo1194 GENDER-STRATIFIED CLINICAL COURSE AND TREATMENT RESPONSE PATTERNS IN EOSINOPHILIC ESOPHAGITIS: A RETROSPECTIVE ANALYSIS AT TWO ACADEMIC CENTERS

2020 ◽  
Vol 158 (6) ◽  
pp. S-822-S-823
Author(s):  
Quan M. Nhu ◽  
Claire P. Witmer ◽  
Nguyen D. Nguyen ◽  
David J. Leung ◽  
Faizi Hai ◽  
...  
Keyword(s):  
Treatment Response ◽  
Retrospective Analysis ◽  
Eosinophilic Esophagitis ◽  
Clinical Course ◽  
Response Patterns

Stimulus Ratio Effects on Speech Discrimination by Children and Adults

1991 ◽  
Vol 34 (3) ◽  
pp. 671-678 ◽  
Author(s):  
Joan E. Sussman
Keyword(s):  
Discrimination Task ◽  
Response Pattern ◽  
Response Patterns ◽  
Speech Discrimination ◽  
Adult Group ◽  
Discrimination Accuracy ◽  
Formant Frequency ◽  
Response Strategies ◽  
Place Of Articulation ◽  
Adults And Children

This investigation examined the response strategies and discrimination accuracy of adults and children aged 5–10 as the ratio of same to different trials was varied across three conditions of a “change/no-change” discrimination task. The conditions varied as follows: (a) a ratio of one-third same to two-thirds different trials (33% same), (b) an equal ratio of same to different trials (50% same), and (c) a ratio of two-thirds same to one-third different trials (67% same). Stimuli were synthetic consonant-vowel syllables that changed along a place of articulation dimension by formant frequency transition. Results showed that all subjects changed their response strategies depending on the ratio of same-to-different trials. The most lax response pattern was observed for the 50% same condition, and the most conservative pattern was observed for the 67% same condition. Adult response patterns were most conservative across condition. Differences in discrimination accuracy as measured by P(C) were found, with the largest difference in the 5- to 6-year-old group and the smallest change in the adult group. These findings suggest that children’s response strategies, like those of adults, can be manipulated by changing the ratio of same-to-different trials. Furthermore, interpretation of sensitivity measures must be referenced to task variables such as the ratio of same-to-different trials.

149: The Effect of Denervation on Signal Transduction Mechanisms of M2 and M3 Mediated Bladder Contractile Response

2005 ◽  
Vol 173 (4S) ◽  
pp. 40-40
Author(s):  
Leo R. Doumanian ◽  
Alan S. Braverman ◽  
Amitt S. Tibb ◽  
Michael R. Ruggieri
Keyword(s):  
Signal Transduction ◽  
Contractile Response ◽  
Transduction Mechanisms

Guidelines Eye Rise in Eosinophilic Esophagitis

2011 ◽  
Vol 44 (13) ◽  
pp. 68
Author(s):  
MICHELE G. SULLIVAN
Keyword(s):  
Eosinophilic Esophagitis

Author response for "Diabetes alters immune response patterns to acute melioidosis in humans"

2019 ◽  
Author(s):  
Barbara Kronsteiner ◽  
Panjaporn Chaichana ◽  
Manutsanun Sumonwiriya ◽  
Kemajitra Jenjaroen ◽  
Fazle Rabbi Chowdhury ◽  
...  
Keyword(s):  
Immune Response ◽  
Author Response ◽  
Response Patterns

Item Bias Analysis of the Young Schema-Questionnaire for Psychopathology, Gender, and Educational Level

2011 ◽  
Vol 27 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Marleen M. Rijkeboer ◽  
Huub van den Bergh ◽  
Jan van den Bout
Keyword(s):  
Educational Level ◽  
Cross Validation ◽  
Item Bias ◽  
Response Patterns ◽  
Dutch Population ◽  
Bias Analysis ◽  
Young Schema Questionnaire ◽  
Item Functioning ◽  
Item Level ◽  
Schema Questionnaire

This study examines the construct validity of the Young Schema-Questionnaire at the item level in a Dutch population. Possible bias of items in relation to the presence or absence of psychopathology, gender, and educational level was analyzed, using a cross-validation design. None of the items of the YSQ exhibited differential item functioning (DIF) for gender, and only one item showed DIF for educational level. Furthermore, item bias analysis did not identify DIF for the presence or absence of psychopathology in as much as 195 of the 205 items comprising the YSQ. Ten items, however, spread over the questionnaire, were found to yield relatively inconsistent response patterns for patients and nonclinical participants.

D-test: A New Test for Analyzing Scale Invariance Using Symbolic Dynamics and Symbolic Entropy

Methodology ◽  
2011 ◽  
Vol 7 (3) ◽  
pp. 88-95 ◽  
Author(s):  
Jose A. Martínez ◽  
Manuel Ruiz Marín
Keyword(s):  
Symbolic Dynamics ◽  
Scale Invariance ◽  
Rating Scales ◽  
Rating Scale ◽  
Marketing Research ◽  
Response Patterns ◽  
Measurement Scales ◽  
Improve Measurement ◽  
Entropy Measures ◽  
The Difference

The aim of this study is to improve measurement in marketing research by constructing a new, simple, nonparametric, consistent, and powerful test to study scale invariance. The test is called D-test. D-test is constructed using symbolic dynamics and symbolic entropy as a measure of the difference between the response patterns which comes from two measurement scales. We also give a standard asymptotic distribution of our statistic. Given that the test is based on entropy measures, it avoids smoothed nonparametric estimation. We applied D-test to a real marketing research to study if scale invariance holds when measuring service quality in a sports service. We considered a free-scale as a reference scale and then we compared it with three widely used rating scales: Likert-type scale from 1 to 5 and from 1 to 7, and semantic-differential scale from −3 to +3. Scale invariance holds for the two latter scales. This test overcomes the shortcomings of other procedures for analyzing scale invariance; and it provides researchers a tool to decide the appropriate rating scale to study specific marketing problems, and how the results of prior studies can be questioned.

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