scholarly journals Pharmacotherapy of cardiovascular comorbidities in osteoporotic postmenopausal women

2017 ◽  
Vol 20 (1) ◽  
pp. 17-21
Author(s):  
Nadezhda V. Izmozherova ◽  
Artem A. Popov
Keyword(s):  
Blood Pressure ◽  
Postmenopausal Women ◽  
Enzyme Inhibitors ◽  
Bone Fractures ◽  
Blood Pressure Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Treatment Needs ◽  
Cross Sectional ◽  
Cardiovascular Comorbidities

Aim: to assess tolerability and efficacy of cardiovascular comorbidities pharmacotherapy in osteoporotic postmenopausal women. Methods: cross-sectional study included 112 osteoporotic postmenopausal women aged from 49 to 85. Results: 95 persons (84.8%) had indications for angiotensine-convertising enzyme inhibitors (ACEI) prescription. Cough was associated with significantly higher odds of coronary heart disease, congestive heart failure and a trend to multiple bone fractures. Valsartan was initiated in 32 coughing patients. Target blood pressure level was reached in 15 women. In 15 cases blood pressure levels decreased by 30% of baseline level. Conclusion: efficacy of cardiovascular diseases in osteoporotic postmenopausal women treatment needs to be assessed in specially designed clinical trials.

scholarly journals Comparison of Urinary Adiponectin in the Presence of Metabolic Syndrome in Peri- and Postmenopausal Women

2021 ◽  
Author(s):  
Patsama Vichinsartvichai ◽  
Rattana Teeramara ◽  
Titima Jirasawas ◽  
Prirayapak Sakoonwatanyoo
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Postmenopausal Women ◽  
Demographic Data ◽  
Diagnostic Value ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Screening And Diagnosis ◽  
Baseline Demographic

Abstract Objectives To find the association between urinary adiponectin and metabolic syndrome (MetS) in peri- and postmenopausal women and its potential application as a noninvasive screening for MetS. Methods A cross-sectional study was conducted in healthy peri- and postmenopausal women (defined by STRAW+10 staging) age at least 40 years who attended annual checkup or menopause clinic were recruited. Baseline demographic data, MENQOL, anthropometric measurements, blood pressure, laboratory (FBS, total cholesterol, HDL-C, LDL-C, TG) and urinary adiponectin were collected. The MetS was diagnosed according to JIS 2009. Results 290 peri- and postmenopausal women had participated. The prevalence of Mets among our participants was 18%. Urinary adiponectin levels were similar in peri- and postmenopausal women with and without MetS (2.6±2.2 vs 2.3±1.9 ng/mL, respectively, P = 0.55). Urinary adiponectin provides no diagnostic value for MetS (AUC = 0.516). Conclusions Urinary adiponectin has no role in screening and diagnosis of MetS in peri- and postmenopausal women. The quest toward noninvasive screening for MetS is still going on.

scholarly journals Agreement between 2017 ACC/AHA Hypertension Clinical Practice Guidelines and Seventh Report of the Joint National Committee Guidelines to Estimate Prevalence of Postmenopausal Hypertension in a Rural Area of Bangladesh: A Cross Sectional Study

Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 315 ◽  
Author(s):  
Barua ◽  
Faruque ◽  
Banik ◽  
Ali
Keyword(s):  
Blood Pressure ◽  
Postmenopausal Women ◽  
Rural Area ◽  
Cross Sectional Study ◽  
Joint National Committee ◽  
Elevated Blood Pressure ◽  
National Committee ◽  
Elevated Blood ◽  
Sectional Study ◽  
Cross Sectional

Background and objectives: Justification for application of 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines to detect hypertension (HTN) among Bangladeshi population is understudied. This prompted us to examine the level of agreement between 2017 ACC/AHA and Joint National Committee 7 (JNC 7) guidelines to detect postmenopausal HTN in a rural area of Bangladesh. Materials and Methods: This cross-sectional study recruited 265 postmenopausal women of 40–70 years of age who visited a rural primary health care centre of Bangladesh. HTN was diagnosed based on two definitions: the JNC 7 guidelines (SBP ≥ 140 or DBP ≥ 90 mmHg), and the 2017 ACC/AHA guidelines (SBP ≥ 130 mmHg, or DBP ≥ 80 mmHg). The prevalence of postmenopausal HTN, its sub-types and stages were reported and compared using frequency and percentage. Agreement was evaluated using Cohen’s Kappa (κ), Prevalence-Adjusted Bias-Adjusted Kappa (PABAK) and First-order Agreement Coefficient (AC1). Results: The prevalence of postmenopausal HTN was 67.5% and 41.9% using 2017 ACC/AHA and JNC 7 guidelines respectively. Among the HTN sub-types and stages, the new 2017 ACC/AHA guideline classified higher proportion of respondents as having isolated systolic hypertension (ISH) (42.6%) and stage 2 HTN (35.8%) compared to JNC 7 (28.7% and 6.8% respectively). On the other hand, the JNC 7 guideline identified more respondents as pre-hypertensive (32.5%) when compared with the 2017 ACC/AHA guideline (3.8%). Between two guidelines, highest agreement was observed for ISH (86.03%) and those had pre-hypertension/elevated blood pressure (71.3%). Similarly, Landis & Koch’s approach detected highest agreement for ISH (κ = 0.74, substantial; PABAK = 0.76, substantial; AC1 = 0.84, excellent; p < 0.001) and pre-hypertension/elevated blood pressure (κ= 0.12, slight; PABAK = 0.42, moderate; AC1 = 0.83, excellent; p < 0.001). Conclusions: The 2017 ACC/AHA HTN guideline reported high agreement and detected more participants as hypertensive when compared with JNC 7 guideline for Bangladeshi postmenopausal women that demands further large-scale study in general population to clarify the current findings more precisely.

scholarly journals Visit patterns at primary care centres and individual blood pressure level – a cross-sectional study

2019 ◽  
Vol 37 (1) ◽  
pp. 53-59 ◽  
Author(s):  
H. Ödesjö ◽  
S. Adamsson Eryd ◽  
S. Franzén ◽  
P. Hjerpe ◽  
K. Manhem ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Primary Care ◽  
Blood Pressure Level ◽  
Cross Sectional Study ◽  
Pressure Level ◽  
Sectional Study ◽  
Cross Sectional

Predictive effect of serum uric acid and blood pressure on the left atrial size in Chinese south population

2020 ◽  
Author(s):  
danhong Fang ◽  
Gaojun Wu ◽  
Qinfen Chen ◽  
Jiansheng Wu ◽  
Shengjie Wu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Left Atrial ◽  
Blood Pressure Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Atrial Size ◽  
Predictive Effect

Abstract Background: Serum uric acid (SUA) is strongly associated with hypertension and is associated with a variety of cardiovascular diseases. In this study we aimed to investigate the predictive effect of SUA and blood pressure on the left atrial (LA) size in Chinese south population. Methods: In this cross-sectional study, we investigated the association between SUA and LA diameter and studied the risk of LA enlargement among subjects with and without hyperuricemia (HU) in different grades of blood pressure in a single-center database (n=5392). Results: The LA diameter was significantly correlated with SUA(r=0.31, P<0.001). The incidence of LA enlargement was significantly greater in subjects with HU than in those without HU [25.7% vs. 14.2%, P<0.001; odds ratio (OR) = 2.09, 95% confidence interval (CI) = (1.78,2.45)], especially in women [21.8% vs. 7.4%, P<0.001; OR=3.50, 95%CI= (2.35, 5.22)]. In subjects with hypertension (≥140/90 mmHg) and HU, the risk of LA enlargement was 7.90 times higher than those with ideal blood pressure (< 120/80 mmHg) and normal SUA [33.1% vs. 5.9%; P<0.001, OR=7.90, 95% CI= (5.87,10.63)]. At the same blood pressure level, the risk of LA enlargement in HU subjects was higher than that in normal SUA (P<0.01). After adjustment for blood pressure, the effect of HU on LA size still exists[public OR=1.82, 95% CI=(1.54,2.14), P<0.001]. Conclusions: HU is an independent risk factor of LA enlargement in Chinese south population. SUA and blood pressure play a synergistic role in predicting the increase of LA diameter. Keywords: Uric acid, Hyperuricemia, Blood pressure, Left atrium

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