scholarly journals The first experience of laser spectroscopy in the surgical treatment of thyroid diseases

2019 ◽  
Vol 45 (1) ◽  
pp. 17-20
Author(s):  
P. S. Vetshev ◽  
K. E. Chilingaridi ◽  
L. I. Ippolitov ◽  
S. S. Harnas ◽  
V. B. Loshchenov ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Surgical Treatment ◽  
Laser Spectroscopy ◽  
Histological Analysis ◽  
Follicle Cell ◽  
Rapid Diagnosis ◽  
Thyroid Diseases ◽  
Subtotal Resection ◽  
Intraoperative Rapid Diagnosis

For assessing the efficacy of intraoperative laser autofluorescent spectroscopy (IOLAS), 46 patients with thyroid diseases of different etiology are examined. The patients ’ aged varied from 30 to 65 years. The following morphological types of diseases were observed: benign nodular formations in 42 patients, thyroid cancer in 4, papillary TINO MO in 2, and follicular cancer TINO MO in 2 cases. Out of benign formations, 36 were multinodular colloid goiter and 6 follicle-cell adenomas. As a result of using IOLAS, thyroid cancer was diagnosed during surgery in 8 (17.4%) out of 36 patients with multinodular colloid goiter; this diagnosis necessitated more extensive intervention than was planned: subtotal resection had to be extended to thyroidectomy. In all the cases IOLAS data were confirmed by urgent and later planned histological analyses. Due to this method, no reoperations were needed, which previously had to be performed because of the data of planned histological analysis, and therefore, the probable complications of reoperations were prevented. Our data indicate that IOLAS more accurately identifies the type and morphology of thyroid involvement and helps choose adequate volume of intervention. The first experience with laser fluorescent study as optic biopsy holds good promise as regards improvement of intraoperative rapid diagnosis of thyroid diseases.

Malignant melanoma of nasal mucosa, ethmoid and frontal sinuses endoscopically resected in the combined transnasal and trans-paralateronasal approach

ORL ro ◽  
2016 ◽  
Vol 3 (1) ◽  
pp. 44-49
Author(s):  
Bogdan Mocanu ◽  
Daniel Mirea ◽  
Silviu Oprescu ◽  
Anca Vișan ◽  
Mihai Tușaliu ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Malignant Melanoma ◽  
Nasal Obstruction ◽  
Nasal Mucosa ◽  
Treatment Plan ◽  
Subtotal Resection ◽  
External Nose ◽  
Frontal Process ◽  
Advanced Stages ◽  
Frontal Sinuses

Introduction. The primitive malignant melanoma of nasal mucosa and paranasal sinus is a rare tumor of uncertain etiology, with unpredictable biologic behavior and bad prognosis. Unlike skin melanomas, there are no risk factors and the disease is frequently manifested in older patients, whose clinical otorhinolaryngology complaints are normally non-specific and ranges from nasal obstruction to rhinorrhea and epistaxis. Unfortunately, this disease is diagnosed basically in advanced stages which makes the surgery difficult. Objective. To report a case of primitive malignant melanoma of nasal mucosa, ethmoid and frontal sinuses, that was diagnosed in 2015. It was performed a subtotal resection in another hospital in 24.08.2015, with a large local reccurence. Report. Our patient was a 78-year-old woman with bilateral nasal obstruction, light epistaxis and unilateral rhinorrhea. The ENT, CT and  MRI exams showed a tumour with important, invasion of the nasal cavity structures (billateral nasal bones, left frontal process of the maxilla, the superior midpoint of the nasal septum, bilateral middle and superior turbinates, left ethmoid and bilateral frontal sinuses). The patient was submited for surgery: total macroscopic resection in the combined endoscopic approach; transnasal and modified lateral rhinotomy with titaniul plates reconstruction of the external nose architecture. Conclusions. Malignant melanomas of nasal mucosa are, in general, diagnosed in advanced stages. Their histological characteristics in the mucosa makes difficult the surgical treatment, which is one of the most efficient options, because they are resistant to chemo and radiotherapy. The early diagnosis and a good surgical treatment plan are the best option for this tumor nowadays.  

Biotin Use Can Interfere with the Management of Thyroid Diseases, Including Thyroid Cancer

2021 ◽  
Vol 33 (12) ◽  
pp. 520-522
Author(s):  
Grigoris Effraimidis ◽  
Linda Maria Hilsted ◽  
Ulla Feldt-Rasmussen
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Diseases

scholarly journals Summary Survey of the Surgical Treatment for Thyroid Diseases

1998 ◽  
Vol 8 (2) ◽  
pp. 125-129
Author(s):  
Hirobumi Kumazawai ◽  
Takuya Tachikawa ◽  
Hisaya Yukawa ◽  
Toshihiko Kaneko ◽  
Toshio Yamashita ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Thyroid Diseases

National Trends in the Surgical Treatment of Non-advanced Medullary Thyroid Cancer (MTC): An Evaluation of Adherence with the 2009 American Thyroid Association Guidelines

2016 ◽  
Vol 40 (12) ◽  
pp. 2930-2940 ◽  
Author(s):  
Eun Hae Estelle Chang ◽  
Waseem Lutfi ◽  
Joseph Feinglass ◽  
Alexandra Eudokia Reiher ◽  
Tricia Moo-Young ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Surgical Treatment ◽  
Medullary Thyroid Cancer ◽  
American Thyroid Association ◽  
Medullary Thyroid ◽  
National Trends

scholarly journals Clinicopathological Characteristics and Prognosis of Papillary Thyroid Carcinoma in Naturally Menopausal Women with Various Durations of Premenarche, Reproductive Periods, and Postmenopausal Stages

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Xuhang Zhu ◽  
Bin Yu ◽  
Yu-qing Huang ◽  
Jing-nan Zhou ◽  
Ming-Hua Ge
Keyword(s):  
Thyroid Cancer ◽  
Surgical Treatment ◽  
Papillary Thyroid Carcinoma ◽  
Cancer Recurrence ◽  
Clinicopathological Characteristics ◽  
Papillary Thyroid ◽  
Recurrence Rates ◽  
Menopausal Women ◽  
Reproductive Life ◽  
Relationship Of

Background. Papillary thyroid cancer (PTC) exhibits a higher incidence in women. Due to various ages at menarche and menopause, estrogen levels vary, which may account for the differences in the occurrence, development, and prognosis of female patients with PTC. Objective. The aim of this study was to investigate the association between various durations in different estrogen levels and PTC and to provide important information to guide clinical management and treatment of this disease. Methods. First, we selected naturally menopausal female study subjects diagnosed with PTC at Zhejiang Cancer Hospital from 2007 to 2012 and then compared the differences in clinicopathological characteristics and prognosis among subjects with various lengths of premenarche, reproductive periods, and postmenopausal stages. Results. We found that all patients showed a significantly higher incidence of tumor multicentricity and intrathyroidal dissemination as the time after menopause increased. Additionally, women with shorter (<30) or longer (>38) reproductive lives had increased recurrence rates of PTC. Conclusions. In this study, we did not find any relationship of self-reported menarche and menopausal ages with the prognosis of PTC patients. More importantly, natural postmenopausal PTC patients with shorter or longer reproductive life, compared to the normal groups, had a higher rate of cancer recurrence and the patients with these characteristics could be recommended a more aggressive surgical treatment.

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