scholarly journals Consensus of expert advices on routing, diagnosis, and management of patients with neuromyelitis optica spectrum disorders

2021 ◽  
Vol 13 (5) ◽  
pp. 140-147
Author(s):  
A. N. Boyko ◽  
K. Z. Bakhtiyarova ◽  
L. V. Brylev ◽  
M. N. Zakharova ◽  
D. S. Kasatkin ◽  
...  

Neuromyelitis optica spectrum disorders (NMOSDs) are autoimmune inflammatory disorders accompanied by central nervous system damage, widespread immunemediated demyelination, and axonal damage, involving mainly the optic nerves, spinal cord, and area postrema. The diagnostic capabilities, administration and routing of patients, and therapeutic approaches to this disease need to be improved. During several expert councils held in 2019–2021 in different regions of the Russian Federation, we discussed multiple issues related to various aspects of medical care for patients with NMOSDs. As a result, the experts developed further steps necessary to improve the medical care to these patients: to write and publish clinical guidelines for the diagnosis and treatment of NMOSDs; to consider the possibility of optimizing the NMOSDs diagnostic program including the aquaporin-4 antibodies (AQP4-IgG) testing; to evaluate the implementation of a set of measures aimed at including the corresponding laboratory investigations into the system of state guarantees (together with the institutions of the Ministry of Health of Russia), if there is clinical and economic feasibility; to include the issues of timely NMOSDs evaluation in educational programs initiated by the scientific medical community, in order to raise awareness of primary care neurologists in relation to the clinical and neuroimaging signs of probable NMOSDs; to assess the possibility of introducing routing schemes for patients with NMOSDs at the regional level; to work out a decision on the collection of NMOSDs epidemiological and clinical data in the Russian Federation.

2019 ◽  
Vol 7 (5) ◽  
pp. 301-302
Author(s):  
Irene Treviño‐Frenk ◽  
Rogelio Dominguez‐Moreno ◽  
Dioselina Panama Tristan‐Samaniego ◽  
David Davila‐Sosa ◽  
Gladys Vanessa Barriga‐Maldonado

2019 ◽  
Vol 26 (2) ◽  
pp. 253-255 ◽  
Author(s):  
Jonathan Ciron ◽  
Fanny Sourdrille ◽  
Damien Biotti ◽  
Thierry Tchoumi ◽  
Anne Ruiz ◽  
...  

Anti–Glial fibrillary acidic protein (GFAP) encephalomyelitis is a recently described entity and while the spectrum of this disease has been explored, further research is needed to fully describe its phenotype. Area postrema syndrome (APS) is usually associated with neuromyelitis optica spectrum disorders (NMOSDs), whereas no case of APS has been previously reported with anti-GFAP encephalomyelitis. In this article, we report a case of APS in a 41-year-old woman in the context of anti-GFAP encephalomyelitis. This case was not associated with additional anti-AQP4 IgG and therefore extends the clinico-radiological spectrum of anti-GFAP encephalomyelitis.


2017 ◽  
Vol 16 (4) ◽  
pp. 154-157

Area postrema syndrome (APS) manifested with hiccups, nausea and vomiting is one of the core clinical findings in neuromyelitis optica spectrum disorders (NMOSD). We report the case of a 41-year-old woman, with no significant prior medical history, who presented with left upper limb paresthesias. The patient revealed two prior episodes, one 5 years ago, with paresthesias and mild paresis on the right side of the body and the other a few month ago, with right peripheral facial palsy, right facial anesthesia, headache, nausea and emesis. This led us to suspect area postrema syndrome and, possibly, NMOSD. Brain MRI did not show typical lesions for NMOSD, apart from a left periaqueductal lesion. Other potential diagnoses were excluded through laboratory workup. Serum anti-AQP4 antibody were negative, while CSF analysis was positive for oligoclonal bands. Based on clinical and paraclinical findings, a diagnosis of MS was made. This case illustrated that APS may also be present in MS and not only in NMOSD.


2018 ◽  
Author(s):  
Christian Lechner ◽  
Matthias Baumann ◽  
Eva-Maria Hennes ◽  
Kathrin Schanda ◽  
Markus Reindl ◽  
...  

2016 ◽  
Vol 3 (2) ◽  
pp. 67-79
Author(s):  
M.Yu. Rykov ◽  
◽  
E.N. Baibarina ◽  
O.V. Chumakova ◽  
V.G. Polyakov ◽  
...  

Author(s):  
P. N. Vanyushin ◽  
A. V. Kuzin ◽  
А. А. Pavlov ◽  
А. V. Nefedov ◽  
N. А. Ivannikova

The article analyzes the current state of the irrigation and drainage systems of the Ryazan region. It is shown that the lack of technical operation of the drainage network led to its failure and failure to perform its functions. Irrigation, in spite of the fact that it gives stability in the years of droughts due to aging and the dismantling of machinery and equipment is not carried out. It is shown that for the reconstruction and / or modernization of irrigation and drainage systems it is necessary on the basis of inventory to determine the environmentally optimal and economically viable systems, their parts and structures that require rehabilitation, reconstruction and / or modernization. The decision to reconstruct may include not only the ameliorative system as a whole, but also some part of it, for example, a canal, pipeline or a separate hydraulic structure, taking into account the justification of economic feasibility. In dry periods, for the Meshcherskaya lowland and areas with peat soils, it is necessary to provide for land-reclamation systems for dual regulation of soil moisture, which reduces the possibility of peat ignition and the spread of fire. It should be borne in mind that the reconstruction of land-reclamation systems has its specific features, which include: socio-economic (increasing the productivity of agricultural land, obtaining additional income, creating modern infrastructure, increasing employment, living conditions, labor, etc.) ; ecological (creation of cultural landscapes, ensuring their ecological sustainability, prevention of land degradation processes, improvement of recreational conditions, elimination of waterlogging, flooding, salinization, erosion, etc.). Reclamation activities are carried out in compliance with the requirements of land, water, forestry legislation of the Russian Federation, as well as the legislation of the Russian Federation on the protection of the environment, on the subsurface, on the plant world and on the animal world.


Author(s):  
Olga Shinkareva

Article is devoted to the analysis of the Order of the Russian Ministry of Health of 19.03.2020 № 198n (an edition of 29.04.2020) “About a temporary order of the organization of work of the medical organizations for implementation of measures for prevention and reduction of risk of spread of a new koronavirusny infection of COVID19” regarding formation of the temporary staff list of the division of the medical organization providing medical care to citizens with a koronavirusny infection of COVID-19 and also the requirement with the staff of this division. The criteria recommended by the Ministry of Health of the Russian Federation for determining the number of rates of medical workers in these divisions, requirements for medical workers of the division have been considered, a practical example of calculation of rates has been given.


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