scholarly journals Acute Changes in Blood Lactate Concentration, Muscle Thickness, and Strength After Walking with Blood Flow Restriction in Older Adults

2016 ◽  
Vol 62 (Suppl.1) ◽  
pp. 237-242 ◽  
Author(s):  
TOSHIHARU NATSUME ◽  
HAYAO OZAKI ◽  
TAKASHI NAKAGATA ◽  
SHUICHI MACHIDA ◽  
HISASHI NAITO
Keyword(s):  
Older Adults ◽  
Blood Flow ◽  
Blood Lactate ◽  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Muscle Thickness ◽  
Blood Flow Restriction ◽  
Flow Restriction ◽  
Acute Changes

Effects of Active Preconditioning With Local and Systemic Hypoxia on Submaximal Cycling

2021 ◽  
pp. 1-6
Author(s):  
Olivier Girard ◽  
Romain Leuenberger ◽  
Sarah J. Willis ◽  
Fabio Borrani ◽  
Grégoire P. Millet
Keyword(s):  
Blood Flow ◽  
Arterial Oxygen Saturation ◽  
Lactate Concentration ◽  
Blood Lactate Concentration ◽  
Blood Flow Restriction ◽  
Arterial Oxygen ◽  
Total Occlusion ◽  
Flow Restriction ◽  
Cycling Efficiency ◽  
Systemic Hypoxia

Purpose: The authors compared the effects of active preconditioning with local and systemic hypoxia during submaximal cycling. Methods: On separate visits, 14 active participants completed 4 trials. Each visit was composed of 1 preconditioning phase followed, after 40 minutes of rest, by 3 × 6-minute cycling bouts (intensity = 85% of critical power; rest = 6 min). The preconditioning phase consisted of 4 × 5-minute cycling bouts at 1.5 W·kg−1 (rest = 5 min) in 4 conditions: control (no occlusion and normoxia), blood flow restriction (60% of total occlusion), HYP (systemic hypoxia; inspired fraction of oxygen = 13.6%), and blood flow restriction + HYP (local and systemic hypoxia combined). Results: During the preconditioning phase, there were main effects of both systemic (all P < .014) and local hypoxia (all P ≤ .001) on heart rate, arterial oxygen saturation, leg discomfort, difficulty of breathing, and blood lactate concentration. Cardiorespiratory variables, gross efficiency, energy cost, and energy expenditure during the last minute of 6-minute cycling bouts did not differ between conditions (all P > .105). Conclusion: Local and systemic hypoxic stimuli, or a combination of both, during active preconditioning did not improve physiological responses such as cycling efficiency during subsequent submaximal cycling.

The influence of exercise load with and without different levels of blood flow restriction on acute changes in muscle thickness and lactate

2016 ◽  
Vol 37 (6) ◽  
pp. 734-740 ◽  
Author(s):  
Jeremy P. Loenneke ◽  
Daeyeol Kim ◽  
Christopher A. Fahs ◽  
Robert S. Thiebaud ◽  
Takashi Abe ◽  
...  
Keyword(s):  
Blood Flow ◽  
Muscle Thickness ◽  
Blood Flow Restriction ◽  
Exercise Load ◽  
Flow Restriction ◽  
Acute Changes ◽  
Different Levels

scholarly journals Effect of Combined Increased Physical Activity and Walking with Blood Flow Restriction on Leg Muscle Thickness in Older Adults

2016 ◽  
Vol 62 (Suppl.1) ◽  
pp. 206-210 ◽  
Author(s):  
HAYAO OZAKI ◽  
TAKASHI NAKAGATA ◽  
TOSHIHARU NATSUME ◽  
SHUICHI MACHIDA ◽  
HISASHI NAITO
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Blood Flow ◽  
Muscle Thickness ◽  
Blood Flow Restriction ◽  
Flow Restriction ◽  
Leg Muscle

Training response to 8 weeks of blood flow restricted training is not improved by preferentially altering tissue hypoxia or lactate accumulation when training to repetition failure

2021 ◽  
Author(s):  
William Neil Morley ◽  
Shane Ferth ◽  
Mathew Ian Bergens Debenham ◽  
Matthew Boston ◽  
Geoffrey Alonzo Power ◽  
...  
Keyword(s):  
High Pressure ◽  
Blood Flow ◽  
Resistance Training ◽  
Blood Lactate ◽  
Blood Flow Restriction ◽  
Moderate Pressure ◽  
Muscular Endurance ◽  
Occlusion Pressure ◽  
Flow Restriction ◽  
Traditional Resistance Training

Despite compelling muscular structure and function changes resulting from blood flow restricted (BFR) resistance training, mechanisms of action remain poorly characterized. Alterations in tissue O2 saturation (TSI%) and metabolites are potential drivers of observed changes, but their relationships with degree of occlusion pressure are unclear. We examined local TSI% and blood lactate (BL) concentration during BFR training to failure using different occlusion pressures on strength, hypertrophy, and muscular endurance over an 8-week training period. Twenty participants (11M:9F) trained 3/wk for 8wk using high pressure (100% resting limb occlusion pressure, LOP, 20%1RM), moderate pressure (50% LOP, 20%1RM), or traditional resistance training (70%1RM). Strength, size, and muscular endurance were measured pre/post training. TSI% and BL were quantified during a training session. Despite overall increases, no group preferentially increased strength, hypertrophy, or muscular endurance (p>0.05). Neither TSI% nor BL concentration differed between groups (p>0.05). Moderate pressure resulted in greater accumulated deoxygenation stress (TSI%*time) (-6352±3081, -3939±1835, -2532±1349 au for moderate pressure, high pressure, and TRT, p=0.018). We demonstrate that BFR training to task-failure elicits similar strength, hypertrophy, and muscular endurance changes to traditional resistance training. Further, varied occlusion pressure does not impact these outcomes, nor elicit changes in TSI% or BL concentrations. Novelty Bullets • Training to task failure with low-load blood flow restriction elicits similar improvements to traditional resistance training, regardless of occlusion pressure. • During blood flow restriction, altering occlusion pressure does not proportionally impact tissue O2 saturation nor blood lactate concentrations

Electromyostimulation with blood flow restriction enhances activation of mTOR and MAPK signaling pathways in rat gastrocnemius muscles

2019 ◽  
Vol 44 (6) ◽  
pp. 637-644
Author(s):  
Toshiharu Natsume ◽  
Toshinori Yoshihara ◽  
Hisashi Naito
Keyword(s):  
Blood Flow ◽  
Signaling Pathways ◽  
Muscle Hypertrophy ◽  
Gastrocnemius Muscle ◽  
Lactate Concentration ◽  
Mapk Signaling ◽  
Blood Flow Restriction ◽  
Mitogen Activated Protein Kinase ◽  
Flow Restriction ◽  
Mapk Signaling Pathways

Neuromuscular electrical stimulation (NMES) combined with blood flow restriction (BFR) induces muscle hypertrophy. However, cellular mechanisms underlying the muscle hypertrophy induced by NMES combined with BFR remain unclear. We tested the hypothesis that NMES combined with BFR would enhance the mechanistic target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK) signaling pathways. Age-matched male Wistar rats (6 months old, n = 7 per group) were assigned randomly to control, BFR alone (BFR), NMES alone (NMES), and NMES combined with BFR (NMES/BFR) groups. NMES induced 25 isometric contractions lasting 8 s with 4-s resting periods between contractions in the gastrocnemius muscle. Four sets in total were performed, with 1-min intervals between sets. A latex cuff was placed on the proximal portion of the hind limb and BFR at 200 mm Hg was conducted in 4 sets (each set 5 min) with 1-min rest intervals between sets. Venous blood was collected from the lateral tail vein to determine pH, H+ concentration, and lactate concentration before and immediately after the treatments. Expression levels of proteins related to muscle hypertrophy were determined by Western blot analysis. The application of NMES/BFR promoted muscle fatigue more than NMES alone. NMES/BFR induced greater changes in accumulation of metabolites and increase in gastrocnemius muscle weight. The phosphorylation of mTOR and MAPK signaling-related proteins was also enhanced following NMES/BFR, compared with other conditions. Thus, NMES enhanced the activation of mTOR and MAPK signaling pathways when combined with BFR.

scholarly journals Strength training with blood flow restriction – a novel therapeutic approach for older adults with sarcopenia? A case report

2019 ◽  
Vol Volume 14 ◽  
pp. 1461-1469 ◽  
Author(s):  
Karynne Grutter Lopes ◽  
Daniel Alexandre Bottino ◽  
Paulo Farinatti ◽  
Maria das Graças Coelho de Souza ◽  
Priscila Alves Maranhão ◽  
...  
Keyword(s):  
Older Adults ◽  
Blood Flow ◽  
Case Report ◽  
Strength Training ◽  
Therapeutic Approach ◽  
Blood Flow Restriction ◽  
Flow Restriction ◽  
Novel Therapeutic

scholarly journals Effects of Low-Load, Elastic Band Resistance Training Combined With Blood Flow Restriction on Muscle Size and Arterial Stiffness in Older Adults

2014 ◽  
Vol 70 (8) ◽  
pp. 950-958 ◽  
Author(s):  
Tomohiro Yasuda ◽  
Kazuya Fukumura ◽  
Yusuke Uchida ◽  
Hitomi Koshi ◽  
Haruko Iida ◽  
...  
Keyword(s):  
Older Adults ◽  
Blood Flow ◽  
Resistance Training ◽  
Arterial Stiffness ◽  
Blood Flow Restriction ◽  
Muscle Size ◽  
Elastic Band ◽  
Flow Restriction ◽  
Low Load

scholarly journals Resistance Training with Blood Flow Restriction Compared to Traditional Resistance Training on Strength and Muscle Mass in Non-Active Older Adults: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (21) ◽  
pp. 11441
Author(s):  
Darío Rodrigo-Mallorca ◽  
Andrés Felipe Loaiza-Betancur ◽  
Pablo Monteagudo ◽  
Cristina Blasco-Lafarga ◽  
Iván Chulvi-Medrano
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Blood Flow ◽  
Resistance Training ◽  
Muscle Mass ◽  
High Intensity ◽  
Meta Analysis ◽  
Small Sample ◽  
Blood Flow Restriction ◽  
Flow Restriction

Low-intensity training with blood flow restriction (LI-BFR) has been suggested as an alternative to high-intensity resistance training for the improvement of strength and muscle mass, becoming advisable for individuals who cannot assume such a load. The systematic review aimed to determine the effectiveness of the LI-BFR compared to dynamic high-intensity resistance training on strength and muscle mass in non-active older adults. A systematic review was conducted according to the Cochrane Handbook and reportedly followed the PRISMA statement. MEDLINE, EMBASE, Web of Science Core Collection, and Scopus databases were searched between September and October 2020. Two reviewers independently selected the studies, extracted data, assessed the risk of bias and the quality of evidence using the GRADE approach. Twelve studies were included in the qualitative synthesis. Meta-analysis pointed out significant differences in maximal voluntary contraction (MVC): SMD 0.61, 95% CI [0.10, 1.11], p = 0.02, I2 71% p < 0.0001; but not in the repetition maximum (RM): SMD 0.07, 95% CI [−0.25, 0.40], p = 0.66, I2 0% p < 0.53; neither in the muscle mass: SMD 0.62, 95% CI [−0.09, 1.34], p = 0.09, I2 59% p = 0.05. Despite important limitations such as scarce literature regarding LI-BFR in older adults, the small sample size in most studies, the still differences in methodology and poor quality in many of them, this systematic review and meta-analysis revealed a positive benefit in non-active older adults. LI- BFR may induce increased muscular strength and muscle mass, at least at a similar extent to that in the traditional high-intensity resistance training.

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