Quantitative automated human chorionic gonadotropin measurement in urine using the Modular Analytics E170 module (Roche)

2005 ◽  
Vol 43 (1) ◽  
Author(s):  
Nasser E. Ajubi ◽  
Nine Nijholt ◽  
Albert Wolthuis
Keyword(s):  
Pregnant Woman ◽  
Detection Limit ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Storage Period ◽  
Manual Labor ◽  
Pregnancy Test ◽  
Automated Methods ◽  
Inter Assay Variation ◽  
Analytical Detection

AbstractOngoing demands on laboratory performance require optimization of processes. An obvious way to achieve this is to reduce manual labor in favor of automated methods. We describe the validation of an automated quantitative urine human chorionic gonadotropin (hCG) analysis on the Roche Modular E170 analyzer to replace the manual qualitative pregnancy test in urine. At urine hCG concentrations of 476, 45 and 11U/L, we found inter-assay variation of 4.3%, 4.3% and 6.8% and average intra-assay variation of 3.0%, 2.6% and 3.0%, respectively. The analytical detection limit was 0.7U/L. We did not detect any loss (due to degradation or adsorption) during a storage period of 5days at 4°C or at −20°C. Recoveries of hCG in urine of a pregnant woman diluted with urine of a pre-menopausal non-pregnant woman (concentration range between 6 and 800mU/L) were between 93% and 112% (y=0.997x−3.843, r

scholarly journals Lung neoplasm mimicking as ectopic pregnancy due to paraneoplastic secretion of human chorionic gonadotropin: a case report and literature review

2021 ◽  
Author(s):  
Jin Peng ◽  
Shangge lv ◽  
Lin Liu ◽  
Shuai Feng ◽  
Naidong Xing
Keyword(s):  
Systematic Review ◽  
Ectopic Pregnancy ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Lung Neoplasm ◽  
High Serum ◽  
Pregnancy Test ◽  
Positive Pregnancy Test ◽  
Β Hcg ◽  
Present Systematic Review

Abstract Purpose The present systematic review aimed to examine the relationship between lung neoplasm and human chorionic gonadotropin (HCG). Especially, women with lung neoplasm mimicking as ectopic pregnancy were explored. Methods A rare case of lung neoplasm with high serum β-HCG, which was initially thought to be ectopic pregnancy, was reported. A literature search was performed of the US National Library of Medicine (MEDLINE), EMBASE, PubMed, and the Cochrane Database of Systematic Reviews using appropriate keywords and subject headings to February 2020. Results Studies assessed lung neoplasm patients with positive HCG were included. Twenty studies, including 24 patients, were included. These cases illustrate the importance of considering the possibility of paraneoplastic secretion of β-HCG in patients who have a positive pregnancy test. This may prevent a delay in the diagnosis and treatment of malignancy in young women. Of the 24 cases, only 7 (29.17%) were managed surgically; others were managed conservatively or with chemotherapy or radiation. Conclusion The present systematic review shows the need to re-awaken awareness and high index of suspicion to lung neoplasm diagnosis in patients with positive pregnancy test.

scholarly journals Post-molar Choriocarcinoma Prevention with MTX Treatment of Persistent Trophoblastic Disease

2019 ◽  
Vol 2 (4) ◽  
pp. 96-97
Author(s):  
Maeda Kazuo ◽  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Pregnancy Test ◽  
Trophoblastic Disease ◽  
Case Number

Aim: Prevention of post molar choriocarcinoma. Methods: 70 mg Methotrexate (MTX) was administered all post molar cases, whose urinary pregnancy test was negative, while 200-300 mg MTX was administered to two persistent trophoblastic disease, whose pregnancy test was positive by human chorionic gonadotropin (hCG). Control was 37 post molar cases, who received no MTX. Post molar examination were repeated in both groups. Results: No choriocarcinoma developed in 107 MTX group, while 3 cases developed choriocarcinoma in 37 nonMTX group. Choriocarcinoma case number was significantly less in MTX groups.

scholarly journals KONSEP ‘IDDAH DENGAN MENGGUNAKAN TES KEHAMILAN PERSPEKTIF MAQASIDUS SYARI’AH

MAQASHID ◽  
2020 ◽  
Vol 3 (1) ◽  
pp. 57-76
Author(s):  
AINUR ROFIQ
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Pregnancy Test

‘Iddah  disyari’atkan bagi perempuan tersebut karena dalam hukum ‘Iddah  mengandung banyak kemaslahatan yang kembali kepada suami, istri, keluarga dan masyarakat. Kemaslahatan ‘Iddah  untuk melindungi dan memelihara keturunan dari ketercampuran dengan laki-laki lain yang akan dinikahi. Sebab, kesucian seorang perempuan selama masa ‘Iddah  tanpa menikah dapat diketahui dari kebebasan dan kekosongan rahimnya dari adanya janin yang ada dalam rahimnya. Perkembangan zaman, ilmu pengetahuan dan teknologi yang canggih, hasil- hasil yang dicapai oleh Ilmu Pengetahuan dan Teknologi (IPTEK) ini luar biasa. Berkat kemajuan teknologi dalam bidang kedokteran dan juga rekayasa manusia yang sangat mengagumkan, kebersihan rahim seorang perempuan dapat diketahui melalui alat tes kehamilan Tespack (Home Pregnancy Test). Tespack bekerja dengan cara mendeteksi hormon HCG (Human Chorionic Gonadotropin) yang terdapat pada urin. Dan hanya dengan menunggu beberapa menit saja rahim seorang wanita dapat diketahui apakah di dalamnya terdapat janin  atau  tidak  dengan  tanda  positif  maupun  negatif. 

False-positive pregnancy test after passive transfusion of ?-human chorionic gonadotropin from donor red blood cells during erythrocytapheresis

Transfusion ◽  
2007 ◽  
Vol 47 (5) ◽  
pp. 788-791 ◽  
Author(s):  
Suresh G. Shelat ◽  
David F. Friedman ◽  
Geralyn M. Meny ◽  
Kim Smith-Whitley ◽  
Dean Carlow ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
False Positive ◽  
Blood Cells ◽  
Pregnancy Test ◽  
Positive Pregnancy Test
Sign in / Sign up

Export Citation Format

Share Document