scholarly journals Timothy Noel is awarded the 2020 IUPAC-ThalesNano Prize for Flow Chemistry

2021 ◽  
Vol 43 (2) ◽  
pp. 27-27
Keyword(s):  
Systems Engineering ◽  
Flow Chemistry ◽  
Micro Fabrication ◽  
Micro Systems ◽  
The University

Abstract The 2020 IUPAC-ThalesNano prize for Flow Chemistry has been awarded to Professor Timothy Noël of the University of Amsterdam’s Van ‘t Hoff Institute for Molecular Sciences. The prize, consisting of an award of USD 7500, honours outstanding contributions in the field of flow chemistry, microfluidics, micro fabrication, and micro systems engineering.

scholarly journals 2020 IUPAC-ThalesNano Prize In Flow Chemistry and Microfluidics–Call For Nominations

2020 ◽  
Vol 42 (2) ◽  
pp. 26-26
Keyword(s):  
Systems Engineering ◽  
Flow Chemistry ◽  
Outstanding Contribution ◽  
Micro Fabrication ◽  
Micro Systems

Abstract The IUPAC-ThalesNano Prize in Flow Chemistry and Microfluidics is to be awarded to an internationally recognized scientist, whose activities or published accounts have made an outstanding contribution in the field of flow chemistry, microfluidics, micro fabrication, and micro systems engineering in academia or industry. Nomination materials should be submitted by 31 May 2020 by visiting the website.

scholarly journals 2020 IUPAC-ThalesNano Prize In Flow Chemistry and Microfluidics—Call For Nominations

2020 ◽  
Vol 42 (3) ◽  
pp. 24-25
Keyword(s):  
Systems Engineering ◽  
Flow Chemistry ◽  
Outstanding Contribution ◽  
Micro Fabrication ◽  
Micro Systems

AbstractThe IUPAC-ThalesNano Prize in Flow Chemistry and Microfluidics is to be awarded to an internationally recognized scientist, whose activities or published accounts have made an outstanding contribution in the field of flow chemistry, microfluidics, micro fabrication, and micro systems engineering in academia or industry.

Utilising the EyasSAT Concept in Space Systems Engineering Courses at the University of Surrey

2006 ◽  
Author(s):  
Major David J. Barnhart ◽  
Dr. Tanya Vladimirova ◽  
Dr. Alex Ellery ◽  
Dr. Vaios J. Lappas ◽  
Dr. Craig I. Underwood ◽  
...  
Keyword(s):  
Systems Engineering ◽  
Space Systems ◽  
The University

Autonomous Control of Non-Silicon MEMS Flexible Micro-Assembly Line

2014 ◽  
Vol 496-500 ◽  
pp. 1468-1472
Author(s):  
Gao Yang Zhang ◽  
Xin Jin ◽  
Zhi Jing Zhang
Keyword(s):  
Assembly Line ◽  
High Volume ◽  
Research Community ◽  
Autonomous Control ◽  
Assembly System ◽  
Micro Fabrication ◽  
Micro Assembly ◽  
Wide Range ◽  
Micro Systems ◽  
Real Challenge

A wide range of micro-components can today be produced using various micro-fabrication techniques. The efficient high volume assembly of complex micro-systems consisting of vast single components (i.e., hybrid micro-systems) is, however, a difficult task that is seen to be a real challenge for the robotic research community. It is necessary to conceive flexible, highly precise and fast micro-assembly methods. In this paper, a frame of a micro-assembly system in the form of flexible micro-assembly line and its autonomous control is presented. Implementation of the control system are described and the procedure of autonomous control is described as well.

Flow Chemistry

2015 ◽  
Author(s):  
Tristan H. Lambert
Keyword(s):  
Continuous Flow ◽  
Flow Chemistry ◽  
Ethyl Vinyl Ether ◽  
University Of Michigan ◽  
Ethyl Vinyl ◽  
Photochemical Rearrangement ◽  
Osaka Prefecture ◽  
La Jolla ◽  
University Of Bristol ◽  
The University

Timothy F. Jamison at MIT developed (Org. Lett. 2013, 15, 710) a metal-free continuous-flow hydrogenation of alkene 1 using the protected hydroxylamine reagent 2 in the presence of free hydroxylamine. The reduction of nitroindole 4 to the corresponding aniline 5 using in situ-generated iron oxide nanocrystals in continuous flow was reported (Angew. Chem. Int. Ed. 2012, 51, 10190) by C. Oliver Kappe at the University of Graz. A flow method for the MPV reduction of ketone 6 to alcohol 7 was disclosed (Org. Lett. 2013, 15, 2278) by Steven V. Ley at the University of Cambridge. Corey R.J. Stephenson, now at the University of Michigan, developed (Chem. Commun. 2013, 49, 4352) a flow deoxygenation of alcohol 8 to yield 9 using visible light photoredox catalysis. Stephen L. Buchwald at MIT demonstrated (J. Am. Chem. Soc. 2012, 134, 12466) that arylated acetaldehyde 11 could be generated from aminopyridine 10 by diazonium formation and subsequent Meerwein arylation of ethyl vinyl ether in flow. The team of Takahide Fukuyama and Ilhyong Ryu at Osaka Prefecture University showed (Org. Lett. 2013, 15, 2794) that p-iodoanisole (12) could be converted to amide 13 via low-pressure carbonylation using carbon monoxide generated from mixing formic and sulfuric acids. The continuous-flow Sonogashira coupling of alkyne 14 to produce 15 using a Pd-Cu dual reactor was developed (Org. Lett. 2013, 15, 65) by Chi-Lik Ken Lee at Singapore Polytechnic. A tandem Sonogashira/cycloisomerization procedure to convert bromopyridine 16 to aminoindolizine 18 in flow was realized (Adv. Synth. Cat. 2012, 354, 2373) by Keith James at Scripps, La Jolla. A procedure for the Pauson-Khand reaction of alkene 19 to produce the bicycle 20 in a photochemical microreactor was reported (Org. Lett. 2013, 15, 2398) by Jun-ichi Yoshida at Kyoto University. Kevin I. Booker-Milburn at the University of Bristol discovered (Angew. Chem. Int. Ed. 2013, 52, 1499) that irradiation of N-butenylpyrrole 21 in flow produced the rearranged tricycle 22. Professor Jamison described (Angew. Chem. Int. Ed. 2013, 52, 4251) a unique peptide coupling involving the photochemical rearrangement of nitrone 23 to the hindered dipeptide 24 in continuous flow.

Flow Chemistry: The Direct Production of Drug Metabolites

2017 ◽  
Author(s):  
Douglass F. Taber
Keyword(s):  
Organic Synthesis ◽  
Flow Chemistry ◽  
Florida State University ◽  
State University ◽  
Max Planck ◽  
Direct Production ◽  
Reactor Technology ◽  
University Of Cambridge ◽  
The University

Several overviews of flow chemistry appeared recently. Katherine S. Elvira and Andrew J. deMello of ETH Zürich wrote (Nature Chem. 2013, 5, 905) on micro­fluidic reactor technology. D. Tyler McQuade of Florida State University and the Max Planck Institute Mühlenberg reviewed (J. Org. Chem. 2013, 78, 6384) applications and equipment. Jun-ichi Yoshida of Kyoto University focused (Chem. Commun. 2013, 49, 9896) on transformations that cannot be effected under batch condi­tions. Detlev Belder of the Universität Leipzig reported (Chem. Commun. 2013, 49, 11644) flow reactions coupled to subsequent micropreparative separations. Leroy Cronin of the University of Glasgow described (Chem. Sci. 2013, 4, 3099) combin­ing 3D printing of an apparatus and liquid handling for convenient chemical synthe­sis and purification. Many of the reactions of organic synthesis have now been adapted to flow con­ditions. We will highlight those transformations that incorporate particularly useful features. One of those is convenient handling of gaseous reagents. C. Oliver Kappe of the Karl-Franzens-University Graz generated (Angew. Chem. Int. Ed. 2013, 52, 10241) diimide in situ to reduce 1 to 2. David J. Cole-Hamilton immobilized (Angew. Chem. Int. Ed. 2013, 52, 9805) Ru DuPHOS on a heteropoly acid support, allowing the flow hydrogenation of neat 3 to 4 in high ee. Steven V. Ley of the University of Cambridge added (Org. Process Res. Dev. 2013, 17, 1183) ammonia to 5 to give the thiourea 6. Alain Favre-Réguillon of the Conservatoire National des Arts et Métiers used (Org. Lett. 2013, 15, 5978) oxygen to directly oxidize the aldehyde 7 to the car­boxylic acid 8. Professor Kappe showed (J. Org. Chem. 2013, 78, 10567) that supercritical ace­tonitrile directly converted an acid 9 to the nitrile 10. Hisao Yoshida of Nagoya University added (Chem. Commun. 2013, 49, 3793) acetonitrile to nitrobenzene 11 to give the para isomer 12 with high regioselectively. Kristin E. Price of Pfizer Groton coupled (Org. Lett. 2013, 15, 4342) 13 to 14 to give 15 with very low loading of the Pd catalyst. Andrew Livingston of Imperial College demonstrated (Org. Process Res. Dev. 2013, 17, 967) the utility of nanofiltration under flow conditions to minimize Pd levels in a Heck product.

Effective NEMS Education and Training in an Undergraduate Course

2012 ◽  
Author(s):  
Nael Barakat ◽  
Heidi Jiao
Keyword(s):  
Undergraduate Students ◽  
Systems Engineering ◽  
Engineering Students ◽  
Educational Process ◽  
Undergraduate Engineering ◽  
Engineering Level ◽  
Hands On ◽  
Manufacturing Techniques ◽  
Increasing Demand ◽  
Micro Systems

Increasing demand on workforce for nanotechnology implementation has resulted in an exponential increase of demand on educational material and methods to qualify this workforce. However, nanotechnology is a field that integrates many areas of science and engineering requiring a significant amount of background knowledge in both theory and application to build upon. This challenge is significantly magnified when trying to teach nanotechnology concepts and applications at the undergraduate engineering level. A considerable amount of time is needed for an undergraduate engineering student to be able to design and build a useful device applying nanotechnology concepts, within one course time. This paper presents an actual experience in teaching hands-on applications in nanotechnology to undergraduate engineering students through an optimized model, within a normal course time. The model significantly reduces the time needed by undergraduate students to learn the necessary manufacturing techniques and apply them to produce useful products at the micro and nano levels, by ensuring that infrastructure and legwork related to the educational process are partially completed and verified, before the course starts. The model also provides improved outcomes as all its pre-course work is also tested with students working under different arrangements of professors’ supervision. The result is an optimized infrastructure setup for micro and nanotechnology design and manufacturing education, built with students in mind, to be completed within the frame of one semester course. The model was implemented at GVSU-SOE as the core hands-on part of a senior undergraduate course titled (EGR 457 nano/micro systems engineering). Students in the course were able to go through the design and build steps of different MEMS and NEMS products, while learning and utilizing cleanroom equipment and procedures. This was based on infrastructural arrangements by students preceding this class by a semester and working closely with the professors. Assessment was conducted on both sides of the model and results were collected for evaluation and improvement of the model.

Development and Description of a Synthetic, High-Fidelity, Emergency Department Patient Dataset for the Evaluation of Healthcare IT Products

2017 ◽  
Vol 6 (1) ◽  
pp. 75-78
Author(s):  
David LaVergne ◽  
Sabrina Casucci ◽  
Nicolette McGeorge ◽  
Theresa Guarrera-Schick ◽  
Lindsey Clark ◽  
...  
Keyword(s):  
Emergency Department ◽  
Systems Engineering ◽  
Emergency Department Patient ◽  
Patient Data ◽  
Patient Privacy ◽  
Suitable Alternative ◽  
Actual Patient ◽  
Research Activities ◽  
Sample Application ◽  
The University

Developing novel interfaces for high-risk situations, such as the Emergency Department, requires a sufficient quantity of detailed patient data to support usability and evaluation activities, yet patient privacy restrictions often prevent the use of actual patient data for these activities. We developed a synthetic dataset to provide a suitable alternative to the use of actual patient data that can be integrated into a variety of research activities. The Emergency Department Information Systems (EDIS) Dataset was developed through close collaboration of experts in Emergency Medicine, Human Factors, and Systems Engineering and provides an ecologically valid set of data for 54 patients, treated in an Emergency Department operating at steady-state, with realistic patient loads and flow. The dataset includes both static and dynamic data for each patient case over a 500-minute time period. A sample application of the dataset is provided to demonstrate how the dataset was used to support the design and evaluation of novel EDIS interface displays and its potential adaptation for future HIT research. This dataset provides a readily adaptable alternative to researchers in need of synthetic patient data to support HIT research and development activities. The EDIS dataset and supporting material are freely available through the University at Buffalo Institutional Repository and can be directly accessed with the URL: hdl.handle.net/10477/75188 .

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