Comparison of the effect of Myrtus communis herbal and anti-hemorrhoid ointments on the hemorrhoid symptoms and quality of life in postpartum women with grade I and II internal hemorrhoid: A triple-blinded randomized controlled clinical trial

Author(s):  
Jamileh Malekuti ◽  
Mojgan Mirghafourvand ◽  
Khadijeh Samadi ◽  
Fatemeh Abbasalizadeh ◽  
Laleh Khodaei

Abstract Introduction Due to the effects of hemorrhoids on physical and mental health, this study aimed to compare the effect of Myrtus communis herbal and anti-hemorrhoid ointments on symptoms of hemorrhoid and quality of life (primary outcomes) and satisfaction of the treatment and side effects (secondary outcomes). Methods This triple-blind randomized controlled trial was performed on women with grade I and II hemorrhoid referring to health centers in Tehran, Iran, in 2017. Individuals were randomly assigned to two groups of 67 people through block randomization method. The intervention group received the Myrtus communis herbal ointment and the control group received anti-hemorrhoid ointment twice a day, every 12 ± 2 h, an applicator of the drug through the rectum for 4 weeks. The Colorectal Evaluation of a Clinical Therapeutics Scale (CORECTS) was used to assess the severity of symptoms of hemorrhoid. To assess the quality of life, the World Health Organization Quality of Life questionnaire (WHOQOL-BREF) was used to measure the general quality of life of participants. This questionnaire was completed once before the start of the study, then on the fourth and the eighth week after the start of the intervention. Repeated measure ANOVA, Chi-square, Mann–Whitney U and independent t-test were used for data analysis. Results The severity of all symptoms of hemorrhoid decreased in both two group and there was no statistically significant difference between the two groups (p>0.05). However, the mean of anal itching at 4 and 8 weeks after the intervention was significantly lower in the Myrtus communis ointment group (p<0.05). There was no significant difference between groups in terms of quality of life at 4 and 8 weeks after the intervention (p>0.05). There was a significant difference between the two groups in terms of satisfaction with the drug (p=0.019) and the participants in the Myrtus communis ointment group were more satisfied with their drug use. Conclusions Myrtus communis herbal ointment was able to reduce the symptoms of hemorrhoid in the affected women. Therefore, it is likely that the use of this drug will promote the health of mothers with hemorrhoid.

Homeopathy ◽  
2021 ◽  
Vol 110 (02) ◽  
pp. 102-107
Author(s):  
Natália S. Champs ◽  
Julia G. Lopes ◽  
Paula C. Sousa ◽  
Clariana C. Souza ◽  
Barbara L.T. Justo ◽  
...  

Abstract Background Despite the increasing demand for complementary and integrative medicine, only a few studies have evaluated the effect of these types of treatments on the quality of life (QoL) of patients with chronic diseases. The objective of this study was to evaluate the QoL of women treated with homeopathy within the Public Health System of Belo Horizonte, Brazil. Methods This is a prospective randomized controlled pragmatic trial. The patients were divided into two independent groups, one group underwent homeopathic treatment in the first 6-month period and the other did not receive any homeopathic treatment. In both randomized groups, patients maintained their conventional medical treatment when necessary. The World Health Organization Quality of Life abbreviated questionnaire (WHOQOL-BREF) was used for QoL analysis prior to treatment and 6 months later. Results Randomization afforded similar baseline results in three domains of QoL analysis for both groups. After 6 months' treatment, there was a statistically significant difference between groups in the physical domain of WHOQOL-BREF: the average score improved to 63.6 ± (SD) 15.8 in the homeopathy group, compared with 53.1 ± (SD) 16.7 in the control group. Conclusions Homeopathic treatment showed a positive impact at 6 months on the QoL of women with chronic diseases. Further studies should be performed to determine the long-term effects of homeopathic treatment on QoL and its determinant factors.


2016 ◽  
Vol 9 (4) ◽  
pp. 174
Author(s):  
Razieh Parnian ◽  
Farzad Poorgholami ◽  
Nehle Parandavar ◽  
Safeih Jamali ◽  
Fatemeh Shakeri

<p><strong>INTRODUCTION:</strong> Infertility is a medical problem which influences all the dimensions of one’s individual and social life and can expose him/her to psycho-physical, socio-economic, sexual and family challenges. This study was designed to compare the quality of life of fertile and infertile women.</p><p><strong>MATERIALS &amp; METHODOLOGY:</strong> This is a case-control analytical study in which 180 fertile and infertile women (aged 18-42) participated. The infertile group consisted of women who had visited an infertility treatment clinic. The fertile group consisted of healthy women who had children and had visited a healthcare center in the city of Jahrom. For the case group (n=90), sampling was conducted based on the census method; for the control group (n=90), subjects were selected through stratified random sampling. Data were collected using a questionnaire which had two sections: demographic information and the World Health Organization quality of life questionnaire (WHO QOL-BREF). The collected data were analyzed using SPSS version 16.</p><p><strong>RESULTS:</strong> The mean age of the participants was 28.26±4.85 years. 76.5% of the infertility cases were due to female infertility and 5.9% were due to male infertility. The results showed that there was a significant difference between the infertile and fertile groups in their overall satisfaction with life levels (p=0.002). There were no significant differences between the two groups in mean scores of somatic, psychological, social and environmental dimensions (p&gt;0.05).</p><p><strong>CONCLUSION:</strong> Considering the results of the present research, it seems that factors like acceptance of infertility by couples, hope for present medical solutions to be effective, use of support plans and recent advancements in technology are possible reasons for the absence of difference between the infertile and fertile groups in quality of life.</p>


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Fatemeh Bagheri ◽  
Azar Nematollahi ◽  
Mehrab Sayadi ◽  
Marzieh Akbarzadeh

Background: Infertility, as an individual and social problem, affects couples’ quality of life and family functioning, job relationships, sexual skills, and marital satisfaction. Objectives: The present study aimed to investigate the relationship between infertility and the quality of life in fertile and infertile women. Methods: In this cross-sectional study with a convenience purposive sampling method, 220 eligible women (110 fertile and 110 infertile) admitted to Shiraz’s healthcare centers were selected. Data collection was conducted using a demographic information questionnaire and the World Health Organization Quality of Life questionnaire. Results: In this study, a total of 220 fertile and infertile women were studied. Our findings showed that the quality of life WHOQOL-BREF score was higher in the fertile group (72.21 ± 12.74) than in the infertile group (69.86 ± 12.58), although not significant. However, the physical area of the quality of life was significantly higher in the fertile group (17.55 ± 3.62) than in the infertile group (16.57 ± 3.55) (P = 0.04). There was no statistically significant difference between the groups concerning other quality of life areas (P > 0.05). Conclusions: The results showed that infertility could reduce the quality of life of infertile women in all areas, and this reduction was significant in the physical area. It appears that infertility diagnostic and therapeutic interventions can affect the quality of life of women in the physical area. Further research is recommended in this field.


Author(s):  
Artur Wdowiak ◽  
Agnieszka Anusiewicz ◽  
Grzegorz Bakalczuk ◽  
Dorota Raczkiewicz ◽  
Paula Janczyk ◽  
...  

The aim of this study was to assess the quality of life (QoL) of infertility treated women as it can affect the effectiveness of therapy. This cross-sectional study was conducted with Abbreviated World Health Organization Quality of Life questionnaire (WHOQOL-BREF), Fertility Quality of Life tool (FertiQoL) and an author’s questionnaire. The study included 1200 women treated for infertility without the use of assisted reproductive technology (non-ART), intrauterine insemination (IUI), or in vitro fertilization (IVF). The control group was 100 healthy women who had children. The time to conceive did not significantly differ between study groups and was 3.1–3.6 years, on average. The quality of life in the WHOQOL-BREF questionnaire data significantly differed between study groups and the control (physical domain p < 0.001, psychological p = 0.009; social p = 0.004; environmental p < 0.001). A significant effect was found in 4 FertiQoL subscales: emotional, biological, partnership, and attitude towards treatment; depending on the method of treatment. Women who received non-ART treatment evaluated their QoL in significantly more negative terms in these 4 subscales, compared to those treated with IVF. The quality of life depends on reproductive problems, methods of infertility treatment, age, place of residence, and education level. Prolongation of the duration of treatment unfavourably affects the quality of life. The quality of life of women undergoing infertility treatment differs according to the mode of work and having children from a previous relationship.


2012 ◽  
Vol 8 (1) ◽  
pp. 152-157 ◽  
Author(s):  
MG Carta ◽  
D Petretto ◽  
S Adamo ◽  
KM Bhat ◽  
ME Lecca ◽  
...  

Introduction:To measure the effectiveness on Quality of Life of adjunctive cognitive behavioral counseling in the setting of General Practitioners (GPs) along with the treatment as usual (TAU;) for the treatment of depression.Methods:Six month-controlled trial of patients who were referred to randomly assigned GPs (four for experimental group of patients and ten for the control) was done. Experimental sample had 34 patients with DSM-IV diagnosis of Depression (Depressed Episode, Dysthymia, or Adjustment Disorder with Depressed Mood) receiving the TAU supplemented with counseling. Control group had 30 patients with diagnosis of Depression receiving only the TAU.Results:The Beck Depression Inventory (BDI) score improved in both groups. Patients in the experimental group showed greater improvement compared to the control group at T2. The World Health Organization Quality OF Life Questionnaire (WHOQOL) score also improved in the experimental group but not in the control group. The improvement in the experimental group was statistically significant in terms of both BDI and WHOQOL scores.Conclusions:Adding counseling to TAU in general medical practice settings is more effective in controlling the symptoms of depression and improving the quality of life as measured over a period of six months, than TAU alone. These results while encouraging, also calls for a larger study involving a largersample size and a longer period of time.


2021 ◽  
Author(s):  
Hyunchan Hwang ◽  
Sun Mi Kim ◽  
Bo Netterstrøm ◽  
Doug Hyun Han

BACKGROUND Stress management within the workplace is important for a healthy mental and physical state. Due to technological advancements, individual-tailored therapy as well as online cognitive-behavioral therapy (CBT) is on the rise. OBJECTIVE This study analyzed the efficacy of a smartphone application based on third-wave CBT tailored to the individual. METHODS A randomized control trial was conducted on 126 participants who were divided into two groups. The intervention group used the smartphone application “BetterLife” for 10 weeks whilst the control group was put on a waiting list for the same duration. The Perceived Stress Scale-10 (PSS), Korean Utrecht Work Engagement Scale-9 (UWES), World Health Organization Quality of Life Assessment, abbreviated (WHOQOL), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) were conducted at baseline and after 10 weeks in both groups. RESULTS Out of the 126 particiapnts, 11 dropped out during the trial. Two-way repeated measure analysis of covariance was conducted controlling for baseline BDI. There were greater improvements in PSS (F=24.33, P <.001, η2=0.17) and UWESK scores (F=8.32, P =.0046, η2=0.06) in the intervention group compared to the control group. WHOQOL scores exhibited statistically significance interactions in the intervention group in the overall quality of life (F=8.19, P =.0049, η2=0.06), and physical health (F= 8.87, P =.003, η2=0.07), psychological (F=13.32, P <.001, η2=0.10), social relationship (F= 19.43, P <.001, η2=0.14), and environmental domains (F= 10.14, P =.002, η2=0.08) but not in overall health (F= 1.68, P =.20). BDI showed a statistically significant improvement in the intervention group (F=7.17, P =.008, η2=0.06) as well as BAI (F=6.00, P =.02, η2=0.05), but this significance did not survive the Bonferroni’s correction (P <.005). CONCLUSIONS These results provide evidence that a smartphone application-based CBT is a viable option for reducing stress in the workplace. CLINICALTRIAL This trial has been registered in the Clinical Research Information Service (KCT0003231), a member of the WHO International Clinical Trials Registry Platform.


2021 ◽  

Background: Menopause is a natural part of women's lives and is associated with a series of complications that can impair their quality of life. This study was conducted to determine the effect of educational interventions based on the Multi-Theory Model (MTM) on the quality of life among menopausal women. Methods: This randomized controlled trial was conducted on 80 menopausal women who met the inclusion criteria and were selected through the multi-stage stratified random sampling method. The participants were randomly allocated to either the control or intervention group (40 subjects per group). The intervention group participated in five 45-min educational sessions based on the MTM on the predetermined days of the week. The quality of life level scores were collected at baseline, immediately, and three months after the intervention using the Menopause-Specific Quality of Life questionnaire (MENQOL). On the other hand, the control group did not receive any intervention during the study period. Results: Analysis of variance of repeated measures showed a significant interaction between time and intervention. Therefore, the independent t-test was used to compare the mean score of quality of life, before, immediately, and three months after the intervention. The results showed a significant difference between the two groups regarding the scores immediately after and three months after the intervention. Conclusion: Structured educational program based on the MTM could be used as a simple and noninvasive intervention that helps menopausal women’s general health through menopausal symptoms relief, thereby improving their quality of life. Further interventions with larger sample sizes may be required to confirm these findings.


2019 ◽  
Author(s):  
Murti Andriastuti ◽  
Pricilia G Halim ◽  
Elnino Tunjungsari ◽  
Dwi P Widodo

Abstract Background: In these last few years, an integrated approach between palliative care (PC) and chronic and/or life-threatening conditions care have been widely used. Home-based PC service is developed to meet the needs of the patients at home, but hasn’t been applied widely. This study is aimed to determine the benefit of integrated home-based PC in the quality of life (QOL) and symtomps intensity of Indonesian children with malignancies. Method: A randomized controlled trial to compare the quality of life between patients who were given PC (a 3-month home visit) and those who were not (intervention vs control group) was conducted, each group containing 30 children with cancer aged 2-18 years old who were consulted to palliative team. Participants were randomly assigned into each group. In the first and twelfth week of the intervention, all patients were assessed with the Pediatric Quality of Life Inventory (PedsQLTM) questionnaire cancer module 3.0 (report by proxy or self-report). Symptoms intensity (pain, anorexia, sleep disturbance) were scored by using Edmonton Symptoms Assessment Scale (ESAS). Mean score and each dimension score of both group were compared and analyzed using bivariate analysis. Results: A total 50 participants were included in analysis. Significant difference was found between two groups with average total score in control group 62.39 and intervention group 81.63 (p<0.001). In the intervention group QoL tends to improve, whereas in the control group, those did not get palliative intervention, quality of life tends to decrease as the disease progress. The most improved aspect in QoL is pain and nausea (p<0.001), followed by procedural anxiety (p=0.002), treatment anxiety (p=0.002), and worry (p=0.014). Palliative intervention was found to be able to reduce sleep disturbances (p=0.003) and anorexia (p<0.001) significantly. Conclusion: Home-based PC improved several aspects of the QOL and provide better symptoms management of children with malignancies. An early intervention concurrent with the underlying treatment is believed to be able to improve their quality of life. Trial Registration: This study has been retrospectively registered in ClinicalTrials.gov ID: NCT04067687 (August, 22nd 2019).


2015 ◽  
Vol 8 (6) ◽  
pp. 179 ◽  
Author(s):  
Zahra Rashid-Tavalai ◽  
Nour Mohammad Bakhshani ◽  
Hamed Amirifard ◽  
Maryam Lashkaripour

<p>Headache is one of the most common complaints in neurological clinics. The current study carried out to determine the benefits of combined Coping Skills Training (CST) and Pharmacotherapy (Ph) for patients with migraine. Forty patients with migraine recruited from the outpatient clinics of Zahedan University of Medical Sciences( Iran) and randomly assigned to one of two treatment groups: the first group received combined coping skills training (CST) and pharmacotherapy(Ph); and the second group received the pharmacotherapy alone(Ph). Five patients due to lack of regular presence or filling out the questionnaires excluded from the study. Finally, the results of 35 subjects were analyzed. Data collection was done using the World Health Organization Quality of Life Questionnaire, General Self-Efficacy Scale-Sherer, Ways of Coping Questionnaire and Migraine Headache Index. The results of ANCOVA on post-test, after controlling the pre-test scores, suggested a significant difference in self-efficacy scores between CST+Ph and Ph groups. Moreover, results of ANCOVA did not show significant differences between the two groups in the scores of pain severity, quality of life, and the use of coping strategies<strong>.</strong> Findings of the present study indicated that coping-skills training, as a psychological intervention, improved self-efficacy. Further longitudinal studies are needed to confirm this conclusion.</p>


2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Laaya Sadat Naghibi ◽  
Saeid Moutavalli

This study aimed to compare mindfulness, psychological well-being and quality of life between working women and housewives district 6 of Tehran. The research method is descriptive and causal-comparative study design. The population of all the housewives and working women of the 6th district of Tehran city with random cluster sampling method and Cochran formula 384, respectively, due to the loss and to ensure the sample size of 400 was determined. Tools of mindfulness questionnaire Brown and Ryan (2003), Psychological well-being questionnaire (2002) and the World Health Organization Quality of Life Questionnaire (1998), respectively. The results showed that between working women and housewives on a scale of mindfulness (p =0/0001) There is a significant difference. Also in the psychological well-being scale (p= 0/0003) and its components, except for component dominate the environment there is a significant difference (p >0/05). Also in the variable quality of life (p =0/0004) and its components were also significantly different (p >0/05). Similarly, the mean indicated in all cases of employed women had higher scores were better off. As a result, we can say they have a positive impact on women’s employment.


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