Analytische und technische Evaluation gereinigter, wiederverwertbarer Küvetten am AMAX 400. Analytical and Technical Evaluation of Washed and Recycled Cuvettes for Determination of Routine Coagulation Assays on an AMAX 400

2001 ◽  
Vol 25 (1-2) ◽  
pp. 31-35
Author(s):  
H. Stiegler ◽  
Yuriko Fischer ◽  
R. Driesch ◽  
A. M. Gressner
Keyword(s):  
Coagulation Assays ◽  
Technical Evaluation ◽  
Routine Coagulation

scholarly journals Fibrin Clot Formation and Lysis in Plasma

2020 ◽  
Vol 3 (4) ◽  
pp. 67
Author(s):  
Julie Brogaard Larsen ◽  
Anne-Mette Hvas
Keyword(s):  
Fibrinolytic Activity ◽  
Research Laboratory ◽  
Ex Vivo ◽  
Fibrin Clot ◽  
Clot Formation ◽  
Coagulation Assays ◽  
Fibrin Formation ◽  
Over Time ◽  
Routine Coagulation

Disturbance in the balance between fibrin formation and fibrinolysis can lead to either bleeding or thrombosis; however, our current routine coagulation assays are not sensitive to altered fibrinolysis. The clot formation and lysis assay is a dynamic plasma-based analysis that assesses the patient’s capacity for fibrin formation and fibrinolysis by adding an activator of coagulation as well as fibrinolysis to plasma and measuring ex vivo fibrin clot formation and breakdown over time. This assay provides detailed information on the fibrinolytic activity but is currently used for research only, as the assay is prone to inter-laboratory variation and as it demands experienced laboratory technicians as well as specialized personnel to validate and interpret the results. Here, we describe a protocol for the clot formation and lysis assay used at our research laboratory.

Bloodhound Missile Evaluation

1962 ◽  
Vol 66 (621) ◽  
pp. 571-587 ◽  
Author(s):  
A. G. Biggs ◽  
A. R. Cawthorne
Keyword(s):  
Scientific Information ◽  
Point Of View ◽  
Operational Performance ◽  
Critical Examination ◽  
List Type ◽  
Complete Evaluation ◽  
Training Requirements ◽  
Detail Design ◽  
Technical Evaluation

The main objectives of Missile Evaluation Trials are a complete evaluation of the operational performance of the missile tested, a comprehensive assessment of the practical implications of regular operation of the weapon system from the user's point of view, and the feedback of scientific information to assist in future designs. This means that the trials must be planned to provide data on the following aspects: —(a) Scientific evaluation, i.e. determination of performance in the various conditions which will arise in operational use.(b) Technical evaluation, i.e. assessment of the detail design, workmanship, engineering and reliability and its influence on operational performance.(c) User evaluation, i.e. a practical critical examination of (and evolution of) handling and servicing procedures, personnel training requirements, installation requirements, logistics, and the numerous organisational steps necessary for the introduction of a new weapon into service.

scholarly journals Preanalytical Variables in Coagulation Testing: Setting the Stage for Accurate Results

2019 ◽  
Vol 45 (05) ◽  
pp. 433-448 ◽  
Author(s):  
Robert C. Gosselin ◽  
Richard A. Marlar
Keyword(s):  
Laboratory Practice ◽  
Coagulation Assays ◽  
Practice Recommendations ◽  
Specimen Collection ◽  
Coagulation Testing ◽  
Specimen Processing ◽  
Processing And Storage ◽  
And Storage ◽  
Routine Coagulation

AbstractMany preanalytical variables may affect the results of routine coagulation assays. While advances in laboratory instrumentation have partially addressed the laboratory's ability to recognize some of these variables, there remains an increased reliance on laboratory personnel to recognize the three potential areas where coagulation testing preanalytical issues may arise: (1) specimen collection (including patient selection), (2) specimen transportation and stability, and (3) specimen processing and storage. The purpose of this article is to identify the preanalytical variables associated with coagulation-related testing and provide laboratory practice recommendations in an effort to improve the quality of coagulation testing and accuracy of result reporting.

scholarly journals Sensitivity of routine coagulation assays to direct oral anticoagulants: patient samples versus commercial drug-specific calibrators

Pathology ◽  
2016 ◽  
Vol 48 (7) ◽  
pp. 712-719 ◽  
Author(s):  
Ming Sheng Lim ◽  
Kent Chapman ◽  
Priscilla Swanepoel ◽  
Anoop K. Enjeti
Keyword(s):  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Coagulation Assays ◽  
Routine Coagulation

Dabigatran assessment in patients with acute complications using routine coagulation assays

2014 ◽  
Vol 25 (5) ◽  
pp. 426-434 ◽  
Author(s):  
Linda Stang ◽  
Susan Nahirniak ◽  
Ken Butcher ◽  
Artur J. Szkotak
Keyword(s):  
Coagulation Assays ◽  
Acute Complications ◽  
Routine Coagulation

Multianalyte Determination of NOACs Using LC-MS/MS and Comparison with Functional Coagulation Assays

2018 ◽  
Vol 64 (10/2018) ◽  
Author(s):  
Ludek Slavik ◽  
Jiri Lukes ◽  
David Friedecky ◽  
Monika Zhanelova ◽  
Marketa Nemcova ◽  
...  
Keyword(s):  
Coagulation Assays
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