scholarly journals Congenital Heart Defects Coexisting with Omphalocele - the Important Prognostic Factor

2018 ◽  
Vol 8 (1) ◽  
pp. 35-41
Author(s):  
Łukasz Sokołowski ◽  
Maria Respondek-Liberska ◽  
Michał Krekora ◽  
Joanna Płużańska ◽  
Maciej Słodki
Keyword(s):  
Congenital Heart ◽  
Septal Defect ◽  
Heart Function ◽  
Heart Defects ◽  
Normal Heart ◽  
Chi Square ◽  
Whitney Test ◽  
Mann Whitney Test ◽  
Chi Square Test ◽  
Heart Anatomy

Abstract Introduction: The aim of this study was to evaluate the following parameters of fetuses and neonates with omphalocele: the prevalence of coexisting congenital heart defects (CHD), abnormalities in heart function and the impact of coexisting CHD on fetal and neonatal survival. Material and methods: The study group consisted of 69 fetuses with omphalocele diagnosed and monitored at the Department of Prenatal Cardiology in our Institute in the years 2007-2017. The retrospective analisis of patients' data was performed. For statistical analysis we used Chi-square test, t-Student test and U Mann-Whitney test.. Results: In the studied group omphalocele was an isolated defect in 31.9% of the cases (22/69), in 68.1% (47/69) coexisting defects were present, in 49.3% (34/69) the coexisting defect was CHD. The most common CHD coexisting with omphalocele were ventricular septal defect (VSD), double outlet right ventricle (DORV) and atrio-ventricular septal defect (AVSD). Abnormalities of heart function were present in 43.5% (30/69) of fetuses with omphalocele: 23.5% (8/34) with normal heart anatomy and in 62.9% (22/35) with CHD. Statistically significant differences between the group with normal heart anatomy and the group with CHD regarded: Cardiovascular Profile Score (CVPS) (median 10 points vs median 9 points, U Mann-Whitney test p=0.034), neonatal birth weight(mean 3253 g vs median 2700 g, U Mann-Whitney test p=0.003), Apgar score (median 8 vs median 7, U Mann-Whitney test p=0.038) and survival rate until discharge from hospital (85% vs 52.9%, Chi-square test p=0.034). The comparison of data from 2007-2017 with data obtained from similar analysis performed in our center in 1999-2006, revealed significant improvement in the early detection of omphalocele (median 14.5 weeks of gestation vs mean 25.4 weeks of gestation), gestational age of delivery (mean 38 weeks of gestation vs mean 34 weeks of gestation) and survival rate until discharge both in neonates with normal heart anatomy and coexisting CHD (85% and 52.9% vs 70% and 23% respectively) . Conclusions: 1. The presence of coexisting CHD is an important prognostic factor in fetuses and neonates with omphalocele, so early fetal echocardiography should be performed in every case of omphalocele. 2. During the last decade (2007-2017), in contrast to years 1999-2006, we observed significant improvement in early and complete prenatal diagnosis of omphalocele. 3. We observed improvement in strategy of obstetrical management resulting in delivering neonates in a more advanced gestational age both in the group with normal heart anatomy and the group with coexisting CHD.

scholarly journals HUBUNGAN PENYAKIT JANTUNG BAWAAN DENGAN STATUS GIZI PADA ANAK DI RSUP PROF. DR. R. D. KANDOU MANADO TAHUN 2009-2013

e-CliniC ◽  
2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Pingkan Putri Maramis ◽  
Erling David Kaunang ◽  
Johnny Rompis
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Nutritional Status ◽  
Atrial Septal Defect ◽  
Congenital Heart ◽  
Septal Defect ◽  
P Value ◽  
Chi Square ◽  
Live Births ◽  
Chi Square Test

Abstract: Congenital heart disease (CHD) is a congenital disorder that is common, with the incidence of 30% of all congenital abnormalities. The incidence of congenital heart disease in developed countries and developing countries ranges from 6-10 cases per 1000 live births, with an average of 8 per 1,000 live births. Nutritional status of a person is basically the person's state of health as a reflection of food consumption and use by the body. Many factors influence the nutritional status of infants and children with congenital heart disease. Nutritional status of patients with CHD is influenced nutrient inputs, energy requirements, dietary components. Objective: Knowing the relationship between congenital heart disease with nutritional status in children.  Methods:  This study is a retrospective analytic approach. The subjects were all children with congenital heart disease who are hospitalized in the Section of Child Health, Prof. Dr.  R. D. Kandou Manado in 2009-2013. The data taken in the form of data gender of the child, the child's age, weight and height as well as nutritional status. Data analysis was performed by Chi-Square test. Result: The number of respondents were 53 children, 34 boys and 19 girls. Types of congenital heart disease is the most common type of Atrial Septal Defect. Most people with experience malnutrition (54.7%), followed by poor nutrition (37.8%) and good nutrition (7.5%). With Chi-Square test of the hypothesis, obtained p-value = 0.045 which suggests a link between congenital heart disease with nutritional status in children. Conclusion: Based on the results of congenital heart disease associated with poor nutritional status in children or less. Keyword: congenital heart disease, nutritional status.   Abstrak: Penyakit jantung bawaan (PJB) merupakan kelainan bawaan yang sering dijumpai, dengan angka kejadian 30% dari seluruh kelainan bawaan.1 Insiden PJB dinegara maju maupun negara berkembang berkisar 6 – 10 kasus per 1000 kelahiran hidup, dengan rata-rata 8 per 1000 kelahiran hidup. Status gizi seseorang pada dasarnya merupakan keadaan kesehatan orang tersebut sebagai refleksi dari konsumsi pangan serta penggunaannya oleh tubuh.1 Banyak faktor ikut mempengaruhi status gizi pada bayi dan anak dengan PJB.2 Status gizi penderita PJB dipengaruhi masukan nutrien, kebutuhan energi, komponen diet.1 Tujuan: Mengetahui adanya hubungan antara penyakit jantung bawaan dengan status gizi pada anak. Metode: Penelitian ini bersifat analitik dengan pendekatan retrospektif. Subjek penelitian adalah semua anak dengan penyakit jantung bawaan yang dirawat inap di Bagian Ilmu Kesehatan Anak RSUP Prof. Dr. R. D. Kandou Manado tahun 2009-2013. Data yang diambil berupa data jenis kelamin anak, umur anak, berat badan dan tinggi badan anak serta status gizi. Analisis data dilakukan dengan uji Chi-Square. Hasil: Jumlah responden sebanyak 53 anak, 34 anak laki-laki dan 19 anak perempuan. Jenis PJB yang paling banyak diderita adalah jenis Atrial Septal Defect. Kebanyakan penderita mengalami gizi kurang (54.7%), diikuti dengan gizi buruk (37.8%) dan gizi baik (7.5%). Dengan uji hipotesis Chi-Square, didapatkan p-value = 0.045 yang menunjukkan adanya hubungan antara penyakit jantung bawaan dengan status gizi pada anak. Simpulan: Berdasarkan hasil penelitian didapatkan penyakit jantung bawaan berhubungan dengan status gizi buruk atau kurang pada anak. Kata Kunci: penyakit jantung bawaan, status gizi.

scholarly journals Debris Extrusion Using Reciproc Blue and XP Endo Shaper Systems in Root Canal Retreatment

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Taher AlOmari ◽  
Rami Al-Fodeh ◽  
Ruba Mustafa ◽  
Hamza El-Farraj ◽  
Waheeb Khaled ◽  
...  
Keyword(s):  
Confidence Level ◽  
Root Canal ◽  
Chi Square ◽  
Whitney Test ◽  
Gutta Percha ◽  
Mann Whitney Test ◽  
Root Canal Retreatment ◽  
Chi Square Test ◽  
Warm Vertical Compaction

This study aimed at assessing the performance of Reciproc Blue (RB) and XP Endo Shaper (XPS), used for canal retreatment on extracted teeth, in terms of debris extrusion and obturating materials removal. Thirty mandibular premolars were prepared to ProTaper X2 file, obturated using warm vertical compaction, and then incubated for 28 days at 100% humidity at 37°C. Teeth were randomly assigned into two groups, according to the system used for retreatment (RB and XPS). During retreatment, debris extruded beyond the apex was collected in preweighed Eppendorf tubes, and the retreatment time was measured. Afterward, the teeth were longitudinally sectioned to assess the remaining obturating materials. Data were statistically analyzed using the Mann–Whitney test and chi-square test at a 95% confidence level. All the samples had extruded debris at varying weights ranging from 0.125 mg to 3.680 mg. XPS extruded less debris than RB, but no difference was detected (Mann–Whitney test; P > 0.05 ). RB and XPS required 54.9 ± 17.9 and 22.3 ± 9.3 seconds to perform retreatment procedures, respectively (Mann–Whitney test; P < 0.05 ). The sealer was found in all the samples. Compared to the RB group, fewer samples with remaining gutta-percha were found in the XPS group (Chi-square test; P < 0.05 ). None of the files fractured during the retreatment procedure. The tested files appear to extrude debris beyond the apex. Although XPS was able to remove the gutta-percha completely from the majority of the canals, it was unable to remove the sealer.

scholarly journals The differences of caries prevalence and caries index of children in primary school with UKGS and without UKGS in Kota Batam

2009 ◽  
Vol 21 (1) ◽  
Author(s):  
Ratna Ayu Alia Zulkarnain ◽  
Eriska Riyanti ◽  
Inne Suherna Sasmita
Keyword(s):  
Statistical Analysis ◽  
Primary School ◽  
Caries Prevalence ◽  
Chi Square ◽  
Whitney Test ◽  
Mann Whitney Test ◽  
Chi Square Test

The purposes of this research were to describe the caries prevalence and caries index of children in primary school with UKGS (SD Kartini I) and without UKGS (SD 009 Bulang) in Kota Batam. Total samples of this research were 193 persons, it is consist of 107 persons from SD Kartini I and 86 persons from SD 009 Bulang. The Chi-Square Test and U Mann-Whitney Test were conducted in this research. The statistical analysis was significant for caries prevalence between children in primary school with UKGS and without UKGS with χ2table = 2.71 and χ2calculate = 3.73, whereas def-t index between children in primary school with UKGS and without UKGS was significant with - Ztable = - 1.96 and Zcalculate = - 2.91 with α = 0.05. The DMF-T index between children in primary school with UKGS and without UKGS was significant with Ztable = 1.96 and Zcalculate = 6.32 with α = 0,05. The conclusions of this study indicate that there were differences of caries prevalence and caries index between children in primary school with UKGS and without UKGS.

scholarly journals Η επίτευξη χειρουργικών ορίων στις μη ψηλαφητές μαστογραφικές αλλοιώσεις του τύπου των μικροαποτιτανώσεων με τη χρήση της ελάχιστα επεμβατικής τεχνικής λήψης ακέραιου ιστοτεμαχίου (BLES)

2019 ◽  
Author(s):  
Αλεξάνδρα Χρήστου
Keyword(s):  
Chi Square ◽  
Whitney Test ◽  
Mann Whitney Test ◽  
Chi Square Test

Σκοπός: η αναδρομική μελέτη της αποτελεσματικότητας της μεθόδου στερεοτακτικής βιοψίας με το σύστημα BLES στην πλήρη αφαίρεση ύποπτων μαστογραφικών αποτιτανώσεων.Υλικό-Μέθοδος: μεταξύ Ιανουαρίου 2014 και Ιανουαρίου 2016, 400 στερεοτακτικές βιοψίες με τη χρήση BLES πραγματοποιήθηκαν στη μονάδα μαστού του Ιπποκράτειου νοσοκομείου λόγω ύποπτων αποτιτανώσεων σε μαστογραφία. Ο μέσος όρος ηλικίας των ασθενών ήταν 58.5 χρονών (κυμαινόμενος από 39-78 χρονών). Η συσκευή BLES χρησιμοποιεί ραδιοσυχνότητες για την αφαίρεση ιστού από το μαστό που περιλαμβάνει την υπό εξέταση βλάβη. Το καλάθι που χρησιμοποιήθηκε σε όλες τις περιπτώσεις ήταν μεγέθους 20 χιλιοστών. Εξετάστηκαν τα ιστολογικά αποτελέσματα από το παρασκεύασμα BLES και συγκρίθηκαν με τα χειρουργικά αποτελέσματα, που χρησιμοποιήθηκαν ως μέθοδος αναφοράς.Αποτελέσματα: σε 90/400 βιοψίες ανευρέθηκε καρκίνος (22.5%) και σε 38/400 βιοψίες ανευρέθηκε καλοήθης αλλοίωση με κυτταρική ατυπία (9.5%). 80% των καρκίνων ήταν DCIS και 20% διηθητικοί καρκίνοι. Το μέσο μέγεθος των αποτιτανώσεων στη μαστογραφία ήταν 15.38 χιλιοστά (st. dev.= 13.579 mm, range 3-78 mm). Πλήρης αφαίρεση των βλαβών επιτεύχθηκε σε 31/90 περιπτώσεις καρκίνων (34.4%) και σε 23/29 περιπτώσεις άτυπων αλλοιώσεων, που χειρουργήθηκαν (76.3%). Προδιαθεσικοί παράγοντες για την επιτυχή αφαίρεση των καρκίνων ήταν το μέγεθος των βλαβών (Mann Whitney test, p<0.001), η απόσταση του καρκίνου από τα όρια του ιστολογικού παρασκευάσματος (Pearson Chi-Square test, p<0.001), η παρουσία νέκρωσης comedo (Pearson Chi-Square test, p=0.014) και ο βαθμός κακοήθειας του καρκίνου (Pearson Chi-Square test, p=0.021). Το πσοστό επιτυχούς εκτομής σε καρκίνους μεγέθους <14 χιλιοστά ήταν 57.4% (31/54 περιπτώσεις). Για τις άτυπες αλλοιώσεις μόνο η απόσταση της βλάβης από τα όρια του παρασκευάσματος αποτέλεσε προδιαθεσικό παράγοντα εκτομής της βλάβης με το σύστημα BLES (p=0.031, Mann Whitney test). Το ποσοστό υποεκτίμησης ήταν 15.5% για τους καρκίνους και μηδενικό για τις περιπτώσεις άτυπων αλλοιώσεων. Το ποσοστό των συνολικών επιπλοκών ήταν 8.75%.Συμπέρασμα: Η στερεοτακτική μέθοδος BLES αποτελεί μια ασφαλή και αποτελεσματική μέθοδο βιοψίας ύποπτων μαστογραφικών αλλοιώσεων με μικρά ποσοστά υποεκτίμησης και υψηλά ποσοστά αφαίρεσης βλαβών που θα μπορούσε πιθανά να χρησιμοποιηθεί σαν θεραπευτική μέθοδο σε επιλεγμένες περιπτώσεις άτυπων βλαβών και καρκίνων καθώς επίσης και να περιορίσει την χειρουργική θεραπευτική προσέγγιση των βλαβών αυτών.

scholarly journals PERBEDAAN STATUS GIZI PADA ANAK DENGAN PENYAKIT JANTUNG BAWAAN SIANOTIK DAN NON SIANOTIK

e-CliniC ◽  
2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Meyrina E. Sondakh ◽  
Erling D. Kaunang ◽  
Novie H. Rampengan
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Ventricular Septal Defect ◽  
Nutritional Status ◽  
Congenital Heart ◽  
Septal Defect ◽  
Physical Growth ◽  
Severe Malnutrition ◽  
Chi Square ◽  
Chi Square Test

Abstract: Congenital Heart Disease (CHD) is a disorder that is commonly found. The incidence of CHD in the world is 8-10 among 1,000 births. Although children with mild or moderate CHD usually have normal growth and development, the presence of CHD can result in physical growth retardation. This study aimed to obtain the difference of nutritional status among children with cyanotic and non-cyanotic CHD. This study was a retrospective analytical study with a cross sectional design. This study was conducted at the Child Health Department Prof. Dr. R. D. Kandou Manado. Data of children treated with CHD from 2009-2014 included age, gender, weight, height, and nutritional status. Data were analyzed with Chi-Square test. Of 55 samples, there were 34 boys and 21 girls. The results showed that the most suffered CHD was ventricular septal defect. There were 54.5% of patients with good enough nutrition, 25.5% with malnutrition, and 16.4% with severe malnutrition. The Chi-Square test obtained a P-value of 0.464 (> 0.050) which indicated that there was no difference in nutritional status among children with cyanotic and non-cyanotic CHD. Conclusion: According to the study there was no difference in nutritional status between cyanotic and non-cyanotic congenital heart disease.Keywords:nutritional status, congenital heart disease, cyanotic, non-cyanoticAbstrak: Penyakit Jantung Bawaan (PJB) merupakan kelainan yang cukup banyak ditemukan. Insidensi PJB di dunia 8-10 di antara 1.000 kelahiran. Anak dengan PJB yang tidak begitu parah biasanya memiliki pertumbuhan dan perkembangan yang normal, tetapi adanya PJB dapat mengakibatkan hambatan pertumbuhan jasmani penderita. Penelitian ini bertujuan untuk mengetahui perbedaan status gizi pada anak dengan PJB sianotik dan non sianotik. Penelitian ini menggunakan metode retrospektif analitik dengan desain potong lintang dan dilaksanakan di Bagian Ilmu Kesehatan Anak BLU RSUP Prof. Dr. R. D. Kandou Manado. Data diambil dari semua anak yang dirawat dengan PJB tahun 2009-2014 meliputi umur, jenis kelamin, berat badan, tinggi badan, dan status gizi anak. Analisis data dilakukan dengan uji Chi-Square. Jumlah sampel 55 anak terdiri dari 34 lelaki dan 21 perempuan. Jenis PJB terbanyak yang diderita ialah ventricular septal defect. Penderita dengan gizi cukup 54,5%; gizi kurang 25,5%; dan gizi buruk 16,4%. Dengan uji Chi-Square, didapatkan nilai P 0,464 (< 0,050) yang menunjukkan tidak terdapat perbedaan status gizi antara anak dengan PJB sianotik dan non sianotik. Simpulan: Tidak terdapat perbedaan status gizi antara penyakit jantung bawaan sianotik dan non sianotik.Kata kunci: status gizi, penyakit jantung bawaan, sianotik, nonsianotik

scholarly journals Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service

2014 ◽  
Vol 32 (2) ◽  
pp. 159-163 ◽  
Author(s):  
Felipe Alves Mourato ◽  
Lúcia Roberta R. Villachan ◽  
Sandra da Silva Mattos
Keyword(s):  
Congenital Heart Disease ◽  
Pulmonary Hypertension ◽  
Down Syndrome ◽  
Heart Disease ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Heart Defects ◽  
Descriptive Analysis ◽  
Atrioventricular Septal Defect

OBJECTIVE:To determine the frequence and profile of congenital heart defects in Down syndrome patients referred to a pediatric cardiologic center, considering the age of referral, gender, type of heart disease diagnosed by transthoracic echocardiography and its association with pulmonary hypertension at the initial diagnosis.METHODS:Cross-sectional study with retrospective data collection of 138 patients with Down syndrome from a total of 17,873 records. Descriptive analysis of the data was performed, using Epi-Info version 7.RESULTS: Among the 138 patients with Down syndrome, females prevailed (56.1%) and 112 (81.2%) were diagnosed with congenital heart disease. The most common lesion was ostium secundum atrial septal defect, present in 51.8%, followed by atrioventricular septal defect, in 46.4%. Ventricular septal defects were present in 27.7%, while tetralogy of Fallot represented 6.3% of the cases. Other cardiac malformations corresponded to 12.5%. Pulmonary hypertension was associated with 37.5% of the heart diseases. Only 35.5% of the patients were referred before six months of age.CONCLUSIONS: The low percentage of referral until six months of age highlights the need for a better tracking of patients with Down syndrome in the context of congenital heart disease, due to the high frequency and progression of pulmonary hypertension.

scholarly journals Pattern and frequency of pediatric congenital heart disease at the Cardiac Research Institute of Kabul Medical University, Afghanistan

2018 ◽  
Vol 58 (3) ◽  
pp. 106-9
Author(s):  
Abdul Muhib Sharifi
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Atrial Septal Defect ◽  
Tetralogy Of Fallot ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Defects ◽  
Cardiac Lesions ◽  
Medical University ◽  
Research Institute

Background Congenital heart disease (CHD) is the most common birth defect, with incidence of 0.7-0.9 live birth; it increases to 2-6% if first degree relative is affected. In Afghanistan majority of births take place at home and routine screening of neonates is not common, so true birth prevalence of CHD cannot be possibly calculated. Therefore, true prevalence of CHD in our population is unknown. Objective To verify the current pattern and frequency distribution of congenital heart disease (CHD) at the Cardiac Research Institute of Kabul Medical University. Methods  This retrospective study was conducted in children aged 0-14 years, who underwent echocardiography for possible congenital heart disease from January 2015 to December 2016. Results  Of 560 patients who underwent echocardiography, 392(70%) had cardiac lesions. Congenital cardiac lesions were found in 235 (60% of those with lesions) patients, while 157 (40%) patients had rheumatic heart disease. Patients with CHD were further subdivided into acyanotic and cyanotic groups. The majority of acyanotic group had isolated atrial septal defect (55%) while the most common lesion in the cyanotic group was Tetralogy of Fallot (42%). Conclusion Congenital heart defects are the most common heart disease in the pediatric population presenting at the Cardiac Research Institute of Kabul Medical University. Atrial septal defect (ASD) was the most common acyanotic defect, while Tetralogy of Fallot (ToF) is the most common cyanotic defect.

scholarly journals Left Ventricular Noncompaction Is More Prevalent in Ventricular Septal Defect Than Other Congenital Heart Defects: A Morphological Study

2020 ◽  
Vol 7 (4) ◽  
pp. 39
Author(s):  
Laís Costa Marques ◽  
Gabriel Romero Liguori ◽  
Ana Carolina Amarante Amarante Souza ◽  
Vera Demarchi Aiello
Keyword(s):  
Ventricular Septal Defect ◽  
Congenital Heart Defects ◽  
Morphological Study ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Defects ◽  
Atrioventricular Septal Defect ◽  
Left Ventricular ◽  
Left Ventricular Noncompaction ◽  
Ventricular Noncompaction

Left ventricular noncompaction (LVNC) is a condition characterized by prominent ventricular trabeculae and deep intertrabecular recesses and has been described as a possible substrate for arrhythmias, thromboembolism, and heart failure. Herein, we explored the prevalence of LVNC morphology among hearts with congenital heart defects (CHD). We examined 259 postnatal hearts with one of the following CHD: isolated ventricular septal defect (VSD); isolated atrial septal defect (ASD); atrioventricular septal defect (AVSD); transposition of the great arteries (TGA); isomerism of the atrial appendages (ISOM); Ebstein’s malformation (EB); Tetralogy of Fallot (TF). Eleven hearts from children who died of non-cardiovascular causes were used as controls. The thickness of the compacted and non-compacted left ventricular myocardial wall was determined and the specimens classified as presenting or not LVNC morphology according to three criteria, as proposed by Chin, Jenni, and Petersen. Normal hearts did not present LVNC, but the CHD group presented different percentages of LVNC in at least one diagnostic criterium. The prevalence of LVNC was respectively, according to Chin’s, Jenni´s and Petersen´s methods: for VSD—54.2%, 35.4%, and 12.5%; ASD—8.3%, 8.3%, and 8.3%; AVSD—2.9%, 2.9%, and 0.0%; TGA—22.6%, 17%, and 5.7%; ISOM—7.1%, 7.1%, and 7.1%; EB—28.6%, 9.5%, and 0.0%; TF—5.9%. 2.9%, and 2.9%. VSD hearts showed a significantly greater risk of presenting LVNC when compared to controls (Chin and Jenni criteria). No other CHD presented similar risk. Current results show some agreement with previous studies, such as LVNC morphology being more prevalent in VSDs. Nonetheless, this is a morphological study and cannot be correlated with symptoms or severity of the CHD.

Sign in / Sign up

Export Citation Format

Share Document