scholarly journals Electronic cigarettes: a systematic review of available studies on health risk assessment

2018 ◽  
Vol 33 (1) ◽  
pp. 43-52 ◽  
Author(s):  
Aziemah Zulkifli ◽  
Emilia Zainal Abidin ◽  
Najihah Zainol Abidin ◽  
Amer Siddiq Amer Nordin ◽  
Sarva Mangala Praveena ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Electronic Cigarettes ◽  
Electronic Cigarette ◽  
Average Daily Dose ◽  
Air Concentration ◽  
Reference Concentration ◽  
Daily Dose

AbstractObjective:This paper primarily aimed to review articles which specifically quantified the risk of electronic cigarette’s (e-cigarette) usage via the health risk assessment (HRA) approach.Methods:Systematic literature searches were conducted using PubMed search engine databases. Search terms such as “electronic cigarette”, “e-cigarette”, “electronic nicotine delivery systems”, “electronic cigarette liquid”, “electronic cigarette vapors”, and “health risk assessment” were used to identify the relevant articles to be included in this review. To enable comparison, hazard quotient (HQ) and lifetime cancer risk (LCR) for the chemicals measured in the selected articles were calculated for three of the articles using the formula: [1] HQ=average daily dose (ADD)/reference dose (RfD) or exposure air concentration (EC)/reference concentration (RfC); [2] LCR=lifetime average daily dose (LADD) × cancer slope factor (CSF) or exposure air concentration (EC) × inhalation unit risk (IUR).Results:Four articles pertaining to HRA of e-cigarettes were critically reviewed, three of the papers focused on specific chemicals namely nicotine, propylene glycol (PG), glycerol and 1,2-propanediol, while one article evaluated the health risks posed by heavy metals contained in e-cigarettes. The calculated HQs for the chemicals in this review had large variations. HQs of the six chemicals, i.e. nicotine, PG, glycerol, cadmium, ethylene glycol, nickel, aluminum and titanium, were found to have the potential to contribute to non-carcinogenic health risks. None of the LCR calculated had risks exceeding the acceptable limit.Conclusion:There are limited HRA studies and the ones that were available provided inconsistent scientific evidences on the health risk characterization arising from the usage of e-cigarettes. As such, there is a need to perform more studies on HRA of e-cigarettes by using uniformed and comprehensive steps and similar reference threshold levels of exposures.

scholarly journals Frequency and Prioritization of Patient Health Risks from a Structured Health Risk Assessment

2014 ◽  
Vol 12 (6) ◽  
pp. 505-513 ◽  
Author(s):  
S. M. Phillips ◽  
R. E. Glasgow ◽  
G. Bello ◽  
M. G. Ory ◽  
B. A. Glenn ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Patient Health

Environmental health risks

2013 ◽  
pp. 178-187
Author(s):  
Roscoe Taylor ◽  
Charles Guest
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Environmental Health ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Health Protection ◽  
Health Threat ◽  
Environmental Health Risks ◽  
Environmental Health Risk

This chapter will help you to understand the environmental health in the rapidly changing context of health protection, the usefulness of having a framework for environmental health risk assessment, and the process of identifying, evaluating, and planning a response to an environmental health threat.

scholarly journals Developing a Public Health Risk Assessment Toolkit for Mass Gatherings and Trialling for an International Multi-Sport Mass Gathering Event

2019 ◽  
Vol 34 (s1) ◽  
pp. s116-s116
Author(s):  
Ellen Bloomer ◽  
Tina Endericks
Keyword(s):  
Public Health ◽  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Planning Process ◽  
Assessment Process ◽  
World Health ◽  
Public Health Risk ◽  
Mass Gatherings

Introduction:Risk assessment for mass gatherings (MGs) is undertaken to enable public health authorities to systematically identify and assess the generic characteristics of an MG, which introduce or enhance particular threats and develop measures to reduce or mitigate these threats. The World Health Organization Collaborating Centres on Mass Gatherings and Global Health Security (WHO CCs) produced a comprehensive guide to MGs called “Public Health for Mass Gatherings: Key Considerations” (KC2). This is being converted into an eLearning resource. A public health risk assessment toolkit is being developed by the WHO CCs to complement and guide organizers in their planning process for the health risks associated with an MG event. Preparations for the Birmingham 2022 Commonwealth Games (BCG) are underway and it is important to involve a public health element in the planning for the BCG.Aim:To develop a public health risk assessment toolkit for MGs and pilot it as part of the planning process for the BCG.Methods:Based on KC2 principles, methods included developing and finalizing a public health risk assessment toolkit for MGs. This study also piloted the toolkit for the BCG.Results:A toolkit will be developed. Key learning will be documented on how the toolkit can be improved. The pilot will identify the key public health risks for the BCG, and assess how to mitigate them.Discussion:The development of this toolkit will be an innovative contribution to the resources available for those organizing MGs. It will support organizers to conduct risk assessments and thus maximize the potential for health from the event. Piloting the toolkit for the BCG is an opportunity for validating it, and provides valuable learning for its use in future events. It will support the risk assessment process for the BCG and share learning regarding the key risks for this event.

scholarly journals Simultaneous Health Risk Assessment of Potentially Toxic Elements in Soils and Sediments of the Guishui River Basin, Beijing

2019 ◽  
Vol 16 (22) ◽  
pp. 4539
Author(s):  
Jiankang Wang ◽  
Bo Gao ◽  
Shuhua Yin ◽  
Dongyu Xu ◽  
Laisheng Liu ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
River Basin ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Ecological Risk ◽  
Toxic Elements ◽  
Potentially Toxic Elements ◽  
Soils And Sediments ◽  
Basin Scale

Simultaneous ecological and health risk assessments of potentially toxic elements in soils and sediments can provide substantial information on their environmental influence at the river-basin scale. Herein, soil and sediment samples were collected from the Guishui River basin to evaluate the pollution situation and the ecological and health risk of potentially toxic elements. Various indexes were utilized for quantitatively assessing their health risks. Pollution assessment by geo-accumulation index showed that Cd had “uncontaminated to moderately polluted” status in the soils and sediments. Potential ecological risk index showed that the Guishui River basin was at low risk in general, but Cd was classified as “moderate or considerable ecological risk” both in the soils and sediments. Health risk assessment calculated human exposure from soils and indicated that both non-carcinogenic and carcinogenic risks of the selected potentially toxic elements were lower than the acceptable levels. Health risks posed by potentially toxic elements bio-accumulated in fish, stemming from sediment resuspension, were also assessed. Non-carcinogenic hazard index indicated no adverse health effects on humans via exposure to sediments; however, in general, Cr contributed largely to health risks among the selected potentially toxic elements. Therefore, special attention needs to be paid to the Guishui River basin in the future.

scholarly journals Health risk assessment by trace elements in an aquatic system in midwestern Brazil

2021 ◽  
Vol 10 (10) ◽  
pp. e398101019037
Author(s):  
Raylane Pereira Gomes ◽  
Thais Reis Oliveira ◽  
Aline Rodrigues Gama ◽  
Fernando Santos Lima ◽  
José Daniel Gonçalves Vieira ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Trace Elements ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Socioeconomic Development ◽  
Hazard Quotient ◽  
Hazard Index ◽  
Carcinogenic Risk ◽  
Risk Indices ◽  
Daily Dose

Water is an important asset for the maintenance of life and socioeconomic development. Aquatic environments have been anthropized, receiving a large polluting load, mainly from trace elements.This study investigates the occurrence of health risks caused by 15 trace elements in the surface water of João Leite stream. Health risk indices were evaluated as average daily dose (ADD), hazard quotient (HQ), hazard index and carcinogenic risk. The risk analysis to human health of the stream João Leite water, indicated that the ADDingestion for the adults had the highest for Fe 1.86E-00 µg/kg/day and lower value for Be 8.0E-05 µg/kg/day. On the other hand, of ADDdermal the highest value was for Fe 5.02E-02 µg/kg/day and, the smallest for Sb 1.54E-05 µg/kg/day. For children to ADDingestion obtained was obtained the highest Fe value 2.60E-00 µg/kg/day and smaller for Be 1.12E-04 µg/kg/day. For ADDdermal the highest value was for Fe 8.58E-02 µg/kg/day and smaller for Sb 2.64E-05 µg/kg/day. HQ for adults ranged from 1.61E-05 to 2.97E-01 for HQingestion and 7.71E-06 to 1.01E-01 for HQdermal. For children 2.25E-05 to 3.74E-01 for HQingestion and 1.32E-05 to 1.73E-01 for HQdermal. The health risk assessment showed that for children, the trace elements present in water have a potentially adverse effect on non-carcinogenic health. The carcinogenic risks were unacceptable for both children and adults. Thus, it is recommended that the use of these waters be limited and that measures be taken to minimize pollution by trace elements.

scholarly journals Occurrence and Health Risk Assessment of Aflatoxins through Intake of Eastern Herbal Medicines Collected from Four Districts of Southern Punjab—Pakistan

2021 ◽  
Vol 18 (18) ◽  
pp. 9531
Author(s):  
Aqib Javed ◽  
Iqra Naeem ◽  
Noreddine Benkerroum ◽  
Muhammad Riaz ◽  
Saeed Akhtar ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Liver Cancer ◽  
Cancer Risk ◽  
Health Risk ◽  
Herbal Medicines ◽  
Average Daily Dose ◽  
Industrial Processing ◽  
Naturally Occurring ◽  
Daily Dose ◽  
Low Exposure

Eastern herbal medicines (HMs) are plant-derived naturally occurring substances with minimum or no industrial processing that have long been used in traditional medicine. Aflatoxins are frequent contaminants of plants. Therefore, these mycotoxins are likely to contaminate HMs and pose a health risk to individuals using them on a regular basis as preventive or curative treatments of various diseases. The present study aimed to determine aflatoxin levels in the most popular Pakistani HM formulations and to assess the health risk associated with the intake of aflatoxins. A total of 400 samples of HM formulations collected from four districts of Punjab were analyzed for the quantification of aflatoxins, out of which 52.5% were found to be contaminated. The average daily dose (ADD) of AFB1 and AFs through the intake of HM formulations ranged between 0.00483 and 0.118 ng/kg bw/day and between 0.00579 and 1.714 ng/kg bw/day, respectively. The margin of exposure (MOE) and population cancer risk ranged from 99.49 to 29378.8 and from 0.00011 to 0.0325 liver cancer cases/105 individuals/year (0.0075–2.455 liver cancer cases/105 individuals/75 years), respectively. Despite the low exposure to aflatoxins from HM formulations in the four studied Punjab (Pakistan) districts, the frequent contamination of the analyzed samples suggests that official measures should be considered to manage the associated risk.

scholarly journals Health Risk Assessment of Groundwater Contaminated by Oil Pollutants Based on Numerical Modeling

2019 ◽  
Vol 16 (18) ◽  
pp. 3245 ◽  
Author(s):  
Xue Bai ◽  
Kai Song ◽  
Jian Liu ◽  
Adam Khalifa Mohamed ◽  
Chenya Mou ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Decision Making ◽  
Numerical Modeling ◽  
Drinking Water ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Reference Sequence ◽  
Decision Making Process ◽  
Theoretical Support

To provide theoretical support for the protection of dispersed drinking water sources of groundwater, we need to accurately evaluate the time and scope of groundwater pollution hazards to human health. This helps the decision-making process for remediation of polluted soil and groundwater in service stations. In this study, we conducted such an evaluation by coupling numerical modeling with a health risk assessment. During the research, soil and groundwater samples were collected and analyzed for 20 pollutants. Fifty-six percent of the heavy contaminants and 100% of the organic contaminants exhibited maximum values at the location of the oil depot. Gray correlation analysis showed that the correlation between background samples and soil underlying the depot was 0.375–0.567 (barely significant to insignificant). The correlation between the reference sequence of other points was 0.950–0.990 (excellent correlation). The correlation of environmental impact after oil depot leakage followed the order: organic pollutants > heavy metals > inorganic pollutants. The groundwater simulation status and predictions indicated that non-carcinogenic health risks covered 25,462 m2 at the time of investigation, and were predicted to extend to 29,593 m2 after five years and to 39,873 m2 after 10 years. Carcinogenic health risks covered 21,390 m2 at the time of investigation, and were predicted to extend to 40,093 m2 after five years and to 53,488 m2 after 10 years. This study provides theoretical support for the protection of a dispersed drinking water source such as groundwater, and also helps the decision-making process for groundwater and soil environment improvement.

Environmental health risks and assessment

2020 ◽  
pp. 196-207
Author(s):  
Wendy Heiger-Bernays ◽  
Kathryn Crawford
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Environmental Health ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Health Protection ◽  
Health Threat ◽  
Environmental Health Risks ◽  
Environmental Health Risk

This chapter will help you appreciate: environmental health in the rapidly changing context of health protection; the utility of having a framework for environmental health risk assessment; the process for conducting an environmental health risk assessment; the major strengths and limitations of risk assessment; the process of identifying, evaluating, and planning a response to an environmental health threat.

Health risk assessment of nitrate pollution in shallow groundwater: a case study in Changchun New District, China

2019 ◽  
pp. 45-58 ◽  
Author(s):  
Hui Tian ◽  
Xiujuan Liang ◽  
Yan Gong ◽  
Zhuang Kang ◽  
Hongtao Jin
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Human Health ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Human Health Risk ◽  
Nitrate Pollution ◽  
Assessment Model ◽  
Potential Health ◽  
Skin Contact

High concentrations of nitrate in groundwater pose a threat to human health. To quantify groundwater nitrate pollution in China's Changchun New District and evaluate its human health risks, 98 groundwater samples were collected and analyzed. The spatial distribution of groundwater chemical components was variable with concentrations descending from TDS > HCO3− > Ca2+ > NO3− > SO42- > Na+ > Cl− > Mg2+ > K+ > NO2− > NH4+. Notably, NO3− concentrations ranged from 0.02–492.72 mg/L and averaged 98.62 mg/L. Over 50% of samples exceeded the Quality Standard for Groundwater of China Class III N threshold (20 mg/L). Principal component analysis determined that NO3 contamination was primarily due to the excessive use of fertilizers in agriculture. A human health risk assessment model was used to assess the potential health risks of groundwater NO3− via drinking water and skin contact pathways. Approximately 90% of adults, 66% of children, and 45% of infants had acceptable health risks in the study area. NO3− exposure risk in the towns of Longjia and Xiyingcheng was the highest, while urban areas tended to have lower exposures. The health risks of residents, especially minors and infants, were concerned.

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