Aluminium (III) Derivatives of Schiff bases Derived from o-Hydroxyacetophenone and Hydroxyalkylamines

1973 ◽  
Vol 28 (1-2) ◽  
pp. 63-68 ◽  
Author(s):  
J. P. Tandon ◽  
R. N. Prasad
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Infrared Spectra ◽  
Aluminium Isopropoxide ◽  
Molecular Weights ◽  
Schiff Base Derivatives ◽  
Derivatives Of

The 1 : 1 and 2 : 3 interactions of aluminium isopropoxide with bifunctional tridentate Schiff bases, derived by the condensation of o-hydroxyacetophenone with hydroxyalkylamines [such as 2-hydroxyethylamine, 2-hydroxy-1-propylamine, 1-hydroxy-2-methyl-2-propylamine and 1-hydroxy-2-butylamine] have been investigated. The resulting derivatives of the types, Al(OPrt)(SB) and Al2(SB)3 (where SB2- is the anion of the corresponding Schiff base, SBH2) have been isolated in almost quantitative yields. The ebullioscopic determination of molecular weights in benzene has shown the isopropoxy derivatives to be dimers, whereas the dialuminium-tris-Schiff base derivatives to be monomers. The infrared spectra of these compounds have been recorded and plausible structures indicated.

Aluminium(III) Derivatives of Monofunctional Bidentate Schiff Bases

1973 ◽  
Vol 28 (3-4) ◽  
pp. 153-157 ◽  
Author(s):  
R. N. Prasad ◽  
J. P. Tandon
Keyword(s):  
Schiff Base ◽  
Ir Spectra ◽  
General Formula ◽  
Schiff Bases ◽  
Molecular Association ◽  
Molecular Weights ◽  
Schiff Base Derivatives ◽  
Stoichiometric Ratios ◽  
Derivatives Of

Reactions of aluminium iso-propoxide with monofunctional bidentate Schiff bases having the general formula 2-HOC10H6CH:NR (where R = C2H5, n C3H7, iso-C3H7, n-C4H9, iso-C4H9, sec-C4H9, tert-C4H9 and C6H5) in different stoichiometric ratios have yielded Al(OPri)2(SB), Al(OPri)(SB)2 and Al(SB)3 type of products (where SB is the anion of the corresponding Schiff base, SBH). The ebullioscopic determination of molecular weights shows that the di-iso-propoxy mono- Schiff base derivatives are dimeric; the tris- Schiff base derivatives are monomeric and for the mono-iso-propoxy bis- Schiff base derivatives, molecular association is ~1.4. The IR spectra of a few representative derivatives have been recorded and possible structures indicated.

Schiff Base Derivatives of Lanthanons / Synthesis of La(III) Pr(III) and Nd(III) Derivatives of Ethylenediamine Bis-2,4-pentanedione

1975 ◽  
Vol 30 (1-2) ◽  
pp. 50-54 ◽  
Author(s):  
S. K. Agarwal ◽  
J. P. Tandon
Keyword(s):  
Molecular Weight ◽  
Schiff Base ◽  
Butyl Alcohol ◽  
Exchange Reactions ◽  
Molecular Weights ◽  
Tetradentate Schiff Base ◽  
Schiff Base Derivatives ◽  
Tert Butyl Alcohol ◽  
Derivatives Of

The 1:1 and 2:3 molar reactions of La(III), Pr(III) and Nd(III) isopropoxides with the bifunctional tetradentate Schiff base, ethylenediamine bis-2,4-pentanedione [AA2(CH2)2H2] have been investigated in the medium of dry benzene.Ln(O-i-C3H7) [AA2(CH2)2] and Ln2[AA2(CH2)2]3 [where, Ln = La(III), Pr(III) or Nd(III) and AA2(CH2)2- 2 anion of the corresponding Schiff base, AA2(CH2)2H2] type of compounds have been obtained in almost quantitative yields and in a state of sufficient purity. The 1:1 derivatives have been shown to undergo exchange reactions with an excess of tert-butyl alcohol leading to the formation of Ln(O-tert-C4H9) [AA2(CH2)2] [where, Ln = La(III), Pr(III) or Nd(III)] type of derivatives. The ebullioscopic determination of molecular weights shows that the 1:1 derivatives are dimeric, whereas 2:3 derivatives are monomeric in boiling benzene. On the basis of elemental analysis, exchange reactions, molecular weight determinations and IR spectra, plausible structures for the resulting 1:1 and 2:3 complexes have been indicated.

Niobium(V) and Tantalum(V) Derivatives of Schiff Bases Derived from β-Hydroxynaphthaldehyde and Acetylacetone with n-Hydroxy-alkylamines

1970 ◽  
Vol 25 (1) ◽  
pp. 32-36 ◽  
Author(s):  
P. Prashar ◽  
J. P. Tandon
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Schiff Base Complexes ◽  
Slight Tendency ◽  
Molar Ratios ◽  
Schiff Base Derivatives ◽  
Metal Atoms ◽  
Derivatives Of

Schiff base derivatives of niobium and tantalum of the types, M(OPri)3SB, M(OPri)(SB)2 and M(SB)2(SBH) have been synthesized by the reactions of the metal isopropoxides with the Schiff bases in 1:1, 1:2 and 1:3 molar ratios (where M=Nb or Ta, SBH⊖ and SB2⊖ represent the corresponding anions of the Schiff bases). Except the triisopropoxy acetylacetone-2-hydroxy-alkylimine derivatives of these metals which are distillable, all the remaining complexes decompose when an attempt is made to distil them. The triisopropoxy mono - Schiff base and the tris - Schiff base derivatives of these metals are essentially monomeric in boiling benzene and probably possess hexa- and octa-coordinated metal atoms, while the monoisopropoxy bis-Schiff base complexes show slight tendency of polymerization.

scholarly journals Adsorption and anti-corrosion characteristics of vanillin Schiff bases on mild steel in 1 M HCl: experimental and theoretical study

RSC Advances ◽  
2020 ◽  
Vol 10 (16) ◽  
pp. 9258-9273 ◽  
Author(s):  
Sanjoy Satpati ◽  
Sourav Kr. Saha ◽  
Aditya Suhasaria ◽  
Priyabrata Banerjee ◽  
Dipankar Sukul
Keyword(s):  
Schiff Base ◽  
Mild Steel ◽  
Schiff Bases ◽  
Theoretical Study ◽  
Schiff Base Derivatives ◽  
Derivatives Of

Two Schiff base derivatives of vanillin and divanillin with 2-picolylamine are synthesized and their anti-corrosive propensity for mild steel in aqueous HCl are compared.

scholarly journals ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES

2019 ◽  
Vol 5 (5) ◽  
pp. 0452-0459
Author(s):  
Ane Francielly Da Silva Santos ◽  
José Roberto Da Silveira Maia
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Schiff Base ◽  
Schiff Bases ◽  
Antimicrobial Effect ◽  
Spectroscopic Methods ◽  
Gram Negative ◽  
Schiff Base Derivatives ◽  
Derivatives Of ◽  
Bacterial Effect

Several organotin(IV) derivatives of phenolic Schiff bases were prepared and investigated by spectroscopic methods. These compounds were bioassayed to evaluate their bacterial effect against Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Salmonella typhimurium) microorganisms. Dimeric and monomeric compounds were characterized by infrared in solid state. Metallic centers having penta-, hexa-, and heptacoordination were identified by multinuclear NMR (1H, 13C and 119Sn) in solution. The di- and triorganotin(IV) derivatives were also investigated by conductimetric measurements in methanol, elemental analysis and melting point. The bioassay of these tin(IV) compounds showed that the best resulting activity was against S. aureus for the triphenyltin(IV) phenolic Schiff base derivatives, presenting MICs of 1.1 µM (0.6 mg mL-1) and 2.2 µM (1.3 mg mL-1).

scholarly journals Characterization of Antimicrobial, Antioxidant, and Leishmanicidal Activities of Schiff Base Derivatives of 4-Aminoantipyrine

Molecules ◽  
2019 ◽  
Vol 24 (15) ◽  
pp. 2696 ◽  
Author(s):  
Teran ◽  
Guevara ◽  
Mora ◽  
Dobronski ◽  
Barreiro-Costa ◽  
...  
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Antimicrobial Activities ◽  
Drug Candidates ◽  
Development Of Resistance ◽  
Schiff Base Derivatives ◽  
Wide Range ◽  
Derivatives Of

Our main interest is the characterization of compounds to support the development of alternatives to currently marketed drugs that are losing effectiveness due to the development of resistance. Schiff bases are promising biologically interesting compounds having a wide range of pharmaceutical properties, including anti-inflammatory, antipyretic, and antimicrobial activities, among others. In this work, we have synthesized 12 Schiff base derivatives of 4-aminoantipyrine. In vitro antimicrobial, antioxidant, and cytotoxicity properties are analyzed, as well as in silico predictive adsorption, distribution, metabolism, and excretion (ADME) and bioactivity scores. Results identify two potential Schiff bases: one effective against E. faecalis and the other with antioxidant activity. Both have reasonable ADME scores and provides a scaffold for developing more effective compounds in the future. Initial studies are usually limited to laboratory in vitro approaches, and following these initial studies, much research is needed before a drug can reach the clinic. Nevertheless, these laboratory approaches are mandatory and constitute a first filter to discriminate among potential drug candidates and chemical compounds that should be discarded.

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