scholarly journals ANTIMICROBIAL EFFECT OF ORGANOTIN COMPOUNDS DERIVED FROM PHENOLIC SCHIFF BASES

2019 ◽  
Vol 5 (5) ◽  
pp. 0452-0459
Author(s):  
Ane Francielly Da Silva Santos ◽  
José Roberto Da Silveira Maia
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Schiff Base ◽  
Schiff Bases ◽  
Antimicrobial Effect ◽  
Spectroscopic Methods ◽  
Gram Negative ◽  
Schiff Base Derivatives ◽  
Derivatives Of ◽  
Bacterial Effect

Several organotin(IV) derivatives of phenolic Schiff bases were prepared and investigated by spectroscopic methods. These compounds were bioassayed to evaluate their bacterial effect against Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Salmonella typhimurium) microorganisms. Dimeric and monomeric compounds were characterized by infrared in solid state. Metallic centers having penta-, hexa-, and heptacoordination were identified by multinuclear NMR (1H, 13C and 119Sn) in solution. The di- and triorganotin(IV) derivatives were also investigated by conductimetric measurements in methanol, elemental analysis and melting point. The bioassay of these tin(IV) compounds showed that the best resulting activity was against S. aureus for the triphenyltin(IV) phenolic Schiff base derivatives, presenting MICs of 1.1 µM (0.6 mg mL-1) and 2.2 µM (1.3 mg mL-1).

scholarly journals A New Prenylated Flavanoid with Antibacterial Activity from Propolis Collected in Egypt

2010 ◽  
Vol 5 (1) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Ashraf El-Bassuony ◽  
Sameh AbouZid
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacillus Cereus ◽  
Spectroscopic Methods ◽  
Gram Positive ◽  
Gram Negative

A novel prenylated flavanoid, isonymphaeol-D (1), together with two known compounds, isonymphaeol-B (2) and nymphaeol-B (3), were isolated from Egyptian propolis. The structures of the isolated compounds were determined by various spectroscopic methods. 1 exhibited antibacterial activity against Gram-positive (Bacillus cereus, Staphylococcus aureus) and Gram-negative strains (Serratia sp., Pseudomonos sp., Escherichia coli).

Aluminium(III) Derivatives of Monofunctional Bidentate Schiff Bases

1973 ◽  
Vol 28 (3-4) ◽  
pp. 153-157 ◽  
Author(s):  
R. N. Prasad ◽  
J. P. Tandon
Keyword(s):  
Schiff Base ◽  
Ir Spectra ◽  
General Formula ◽  
Schiff Bases ◽  
Molecular Association ◽  
Molecular Weights ◽  
Schiff Base Derivatives ◽  
Stoichiometric Ratios ◽  
Derivatives Of

Reactions of aluminium iso-propoxide with monofunctional bidentate Schiff bases having the general formula 2-HOC10H6CH:NR (where R = C2H5, n C3H7, iso-C3H7, n-C4H9, iso-C4H9, sec-C4H9, tert-C4H9 and C6H5) in different stoichiometric ratios have yielded Al(OPri)2(SB), Al(OPri)(SB)2 and Al(SB)3 type of products (where SB is the anion of the corresponding Schiff base, SBH). The ebullioscopic determination of molecular weights shows that the di-iso-propoxy mono- Schiff base derivatives are dimeric; the tris- Schiff base derivatives are monomeric and for the mono-iso-propoxy bis- Schiff base derivatives, molecular association is ~1.4. The IR spectra of a few representative derivatives have been recorded and possible structures indicated.

Niobium(V) and Tantalum(V) Derivatives of Schiff Bases Derived from β-Hydroxynaphthaldehyde and Acetylacetone with n-Hydroxy-alkylamines

1970 ◽  
Vol 25 (1) ◽  
pp. 32-36 ◽  
Author(s):  
P. Prashar ◽  
J. P. Tandon
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Schiff Base Complexes ◽  
Slight Tendency ◽  
Molar Ratios ◽  
Schiff Base Derivatives ◽  
Metal Atoms ◽  
Derivatives Of

Schiff base derivatives of niobium and tantalum of the types, M(OPri)3SB, M(OPri)(SB)2 and M(SB)2(SBH) have been synthesized by the reactions of the metal isopropoxides with the Schiff bases in 1:1, 1:2 and 1:3 molar ratios (where M=Nb or Ta, SBH⊖ and SB2⊖ represent the corresponding anions of the Schiff bases). Except the triisopropoxy acetylacetone-2-hydroxy-alkylimine derivatives of these metals which are distillable, all the remaining complexes decompose when an attempt is made to distil them. The triisopropoxy mono - Schiff base and the tris - Schiff base derivatives of these metals are essentially monomeric in boiling benzene and probably possess hexa- and octa-coordinated metal atoms, while the monoisopropoxy bis-Schiff base complexes show slight tendency of polymerization.

scholarly journals Adsorption and anti-corrosion characteristics of vanillin Schiff bases on mild steel in 1 M HCl: experimental and theoretical study

RSC Advances ◽  
2020 ◽  
Vol 10 (16) ◽  
pp. 9258-9273 ◽  
Author(s):  
Sanjoy Satpati ◽  
Sourav Kr. Saha ◽  
Aditya Suhasaria ◽  
Priyabrata Banerjee ◽  
Dipankar Sukul
Keyword(s):  
Schiff Base ◽  
Mild Steel ◽  
Schiff Bases ◽  
Theoretical Study ◽  
Schiff Base Derivatives ◽  
Derivatives Of

Two Schiff base derivatives of vanillin and divanillin with 2-picolylamine are synthesized and their anti-corrosive propensity for mild steel in aqueous HCl are compared.

scholarly journals Synthesis, characterization and antimicrobial activity of copper(II) Schiff base adducts of some p-substituted aniline Schiff bases

2021 ◽  
Vol 35 (1) ◽  
pp. 33-42
Author(s):  
A. O. Sobola ◽  
G. M. Watkins ◽  
R. O. Shaibu ◽  
S. Adewuyi ◽  
S. A. Amolegbe
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Schiff Base ◽  
Schiff Bases ◽  
Conductivity Measurement ◽  
Metal Chelates ◽  
Schiff Base Ligands ◽  
Subtilis Subsp

The synthesis, characterization and antimicrobial activity of Cu(II) complexes of some p-substituted aniline Schiff base ligands have been carried out. The Schiff bases were obtained from salicylaldehyde and o-vanillin. The Cu(II) complexes have been characterized by elemental analysis, conductivity measurement, infrared and electronic spectral data. The complexes were obtained either as metal chelates [Cu(L)2] or Schiff base adducts (CuCl2.2LH).xH2O. The metal chelates were non-electrolytes while the Schiff base adducts exhibited 1:1 or 2:1 electrolytes in methanol. The Cu(II) complexes exhibited slight antimicrobial activity against Escherichia coli ATCC® 8739™*, Staphylococcus aureus subsp. aureus ATCC® 6538™*, Bacillus subtilis subsp. spizizenii ATCC® 6633™* and Candida albicans ATCC® 2091™*. The complexes exhibited significant antifungal activity.                     KEY WORDS: Metal Chelates, Schiff bases, Adducts, Cu(II) complexes, Salicylaldimines   Bull. Chem. Soc. Ethiop. 2021, 35(1), 33-42. DOI: https://dx.doi.org/10.4314/bcse.v35i1.3

scholarly journals The Influence of the Structure of Several New ortho-Hydroxy-Ketone Derived bis-Schiff Bases on Their Antibacterial and Anti-Inflammatory Activity

2020 ◽  
Vol 71 (1) ◽  
pp. 244-248
Author(s):  
Gladiola Tantaru ◽  
Mihai Apostu ◽  
Cristina Mihaela Ghiciuc ◽  
Antonia Poiata ◽  
Alina Stefanache ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Schiff Bases ◽  
Antimicrobial Activities ◽  
Hydroxy Ketone ◽  
Gram Negative Bacteria ◽  
Anti Inflammatory ◽  
Derivatives Of ◽  
Inflammatory Effect

The article presents some bis-Schiff bases - halogenated derivatives of ortho-hydroxy-ketones - with great potential for antimicrobial and antiinflammatory activity. The antimicrobial activities of the Schiff bases were tested in comparison with Chloramphenicol, Nystatin, and Ampicillin upon the following strains: Staphylococcus aureus (ATCC 25923), Sarcina lutea (ATCC 9341), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 1023), Candida glabrata, two Staphylococcus aureus strains, and several clinical isolates (Proteus mirabilis, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae). Those compounds were found to be active against Gram-positive or Gram-negative bacteria, and had an anti-inflammatory effect comparable to that of Indomethacin.

Microwave-assisted synthesis and antibacterial activity of derivatives of 3-[1-(4-fluorobenzyl)-1H-indol-3-yl]-5-(4-fluorobenzylthio)-4H-1,2,4-triazol-4-amine

2014 ◽  
Vol 68 (3) ◽  
Author(s):  
Yong-Le Peng ◽  
Xing-Li Liu ◽  
Xiao-Hong Wang ◽  
Zhi-Gang Zhao
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Inhibitory Concentration ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted ◽  
Schiff Base Derivatives ◽  
Excellent Method ◽  
Derivatives Of

AbstractHerein, an excellent method for the synthesis of twelve novel Schiff base derivatives containing indole and triazole assisted by microwave irradiation is reported. Compared with the conventional method, the yields increased from 59–84 % to 85–96 % and the reaction time was reduced from 24–30 h to 4–8 min. Moreover, all series of the newly synthesized Schiff bases were evaluated for their antibacterial activity. The values of minimum inhibitory concentration (MIC) and IC50 indicated that many target compounds possessed excellent antibacterial activity against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Bacillus subtilis.

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