Four Additional Meroterpenes Produced by Penicillium sp Found in Association with Melia azedarach. Possible Biosynthetic Intermediates to Austin

2007 ◽  
Vol 62 (8) ◽  
pp. 1035-1044 ◽  
Author(s):  
Taicia Pacheco Fill ◽  
Grace Kelli Pereira ◽  
Regina M. Geris dos Santos ◽  
Edson Rodrigues-Fo
Keyword(s):  
Nmr Spectroscopy ◽  
Spectroscopic Studies ◽  
Melia Azedarach ◽  
Root Bark ◽  
Penicillium Sp ◽  
New Compounds

Four additional meroterpenes were isolated and identified from rice cultures of Penicillium sp, a fungus obtained from the root bark of Melia azedarach. These new compounds were named preaustinoid B2 (1), preaustinoid A3 (2), austinolide (3), and isoaustinone (4) in analogy with the formerly described compounds. The structures were identified by extensive spectroscopic studies, including 1 D and 2 D NMR spectroscopy and HRMS. Compounds 1 - 4 are probably biosynthetic intermediates to Austin.

Further Meroterpenes Produced by Penicillium sp., an Endophyte Obtained from Melia azedarach

2003 ◽  
Vol 58 (9-10) ◽  
pp. 663-669 ◽  
Author(s):  
Regina M. Geris dos Santos ◽  
Edson Rodrigues-Fo.
Keyword(s):  
Spectroscopic Studies ◽  
Melia Azedarach ◽  
Root Bark ◽  
Surface Sterilization ◽  
Penicillium Sp

AbstractFrom the methanolextract of Penicillium sp. cultivated on sterilized rice for three weeks we isolated three new meroterpenes preaustinoid A1, A2 and B1. The fungus was isolated from the root bark of Melia azedarach after surface sterilization. The structures of these compounds were identified by intensive spectroscopic studies.

New Pyrrolo[1,2-b]pyridazine Derivatives by 1,3-Dipolar Cycloaddition of Mesoionic Oxazolopyridazinone

2008 ◽  
Vol 59 (11) ◽  
Author(s):  
Miron Teodor Caproiu ◽  
Florea Dumitrascu ◽  
Mino R. Caira
Keyword(s):  
Nmr Spectroscopy ◽  
Elemental Analysis ◽  
Cycloaddition Reaction ◽  
Dipolar Cycloaddition ◽  
Pyridazine Derivatives ◽  
New Compounds

New pyrrolo[1,2-b]pyridazine derivatives 8a-f were synthesized by 1,3-dipolar cycloaddition reaction between mesoionic 1,3-oxazolo[3,2-b]pyridazinium-2-oxides and diethyl or diisopropyl acetylenedicarboxylate as alkyne dipolarophiles. The structures of the new compounds were assigned by elemental analysis and NMR spectroscopy.

Unexpected Keto-enol Tautomerism in the Cyclopyridinophane Class Direct and indirect proofs

2008 ◽  
Vol 59 (10) ◽  
Author(s):  
Paul Ionut Dron ◽  
Neculai Doru Miron ◽  
Gheorghe Surpateanu
Keyword(s):  
Nmr Spectroscopy ◽  
1H Nmr ◽  
Stable Conformer ◽  
Ph Measurements ◽  
Theoretical Methods ◽  
Nmr Data ◽  
Tautomeric Forms ◽  
New Compounds

The paper presents the synthesis of cyclo (bis-paraquat p-phenylene p-phenylene-carbonyl) tetrakis (hexafluorophosphate), named �CETOBOX�, and the closely related structural determinations. This compound exists in three tautomeric forms. These forms were evidentiated by NMR-data (1H-NMR, TOCSY, COSY, NOESY), UV-Vis spectra coupled with pH measurements and by synthesis. As the �CETOBOX� gives �in situ� only the corresponding monoylide, the synthesis of a new fluorescent indolizine cyclophane has been performed by a 3+2 cycloaddition. All structures of the new compounds presented herein have been established by NMR spectroscopy. Also, theoretical methods (MM3, AM1, AM1-COSMO and B88LYPDFT) have been used to determine the most stable conformer structures.

scholarly journals Tanzawaic acids I–L: Four new polyketides from Penicillium sp. IBWF104-06

2014 ◽  
Vol 10 ◽  
pp. 251-258 ◽  
Author(s):  
Louis P Sandjo ◽  
Eckhard Thines ◽  
Till Opatz ◽  
Anja Schüffler
Keyword(s):  
Soil Sample ◽  
Magnaporthe Oryzae ◽  
Rice Blast ◽  
Rice Blast Fungus ◽  
Fungal Strain ◽  
Conidial Germination ◽  
Penicillium Sp ◽  
Culture Filtrates ◽  
Blast Fungus ◽  
New Compounds

Four new polyketides have been identified in culture filtrates of the fungal strain Penicillium sp. IBWF104-06 isolated from a soil sample. They are structurally based on the same trans-decalinpentanoic acid skeleton as tanzawaic acids A–H. One of the new compounds was found to inhibit the conidial germination in the rice blast fungus Magnaporthe oryzae at concentrations of 25 μg/mL.

scholarly journals Synthesis, characterization and acute toxicity of new Schiff base derived from phenylethyl amine and 2-hydroxy naphthaldehyde

2019 ◽  
Vol 10 (1) ◽  
pp. 26-29
Author(s):  
Ibtihal Hassan Hatim ◽  
Wasfi Aboud Al-Masoudi ◽  
Rashad Fadhil Ghadhban
Keyword(s):  
Body Weight ◽  
Schiff Base ◽  
Nmr Spectroscopy ◽  
Acute Toxicity ◽  
Elemental Analysis ◽  
Good Yield ◽  
Mice Model ◽  
Base Derivative ◽  
New Compounds

There is an urgent need for the design and development of new and safer drugs, this has attracted organic chemists to synthesize new compounds with potential of biological and chemotherapeutic activities. Here we report, the condensation of phenylethylamine with 2-hydroxy naphthaldehyde yielded Schiff base derivative in good yield. Characterization of synthesized compound was carried by elemental analysis, IR, 1H-, 13C- and HSQC-NMR spectroscopy. The toxicity of the synthesized compound was determined using Balb/c mice model. Dixon’s up and down method was found to have an LD50 of 827.2 mg/kg of body weight, moderate toxicity.

Methansulfinylchlorid-Lewissäure-Addukte CH3S(Cl)OMF5 (M = As, Sb) und Kristallstruktur von CH3S(Cl)OSbCl5 [1] / Methanesulfinylchloride Lewis Acid Adducts CH3S(Cl)OMF5 (M = As, Sb) and Crystal Structure of CH3S(Cl)OSbCl5 [1]

1996 ◽  
Vol 51 (1) ◽  
pp. 133-138 ◽  
Author(s):  
Rolf Minkwitz ◽  
Ulrike Lohmann ◽  
Hans Preut
Keyword(s):  
Crystal Structure ◽  
Nmr Spectroscopy ◽  
Lewis Acid ◽  
Unit Cell ◽  
Monoclinic Space Group ◽  
Space Group ◽  
New Compounds ◽  
Lewis Acid Adducts

Abstract CH3S(0)C1 reacts in HF as solvent with MF5 (M = As, Sb) to give products CH3S(Cl)OMF5 (M = As, Sb). The new compounds are stable below 253 K and were charac­ terized by Raman and NMR spectroscopy.In addition, the crystal structure of CH3S(Cl)OSbCl5 has been determinated. The complex crystallizes in the monoclinic space group P21/n with a = 644.3(5), b = 1905.9(14), c = 900.0(7) pm, β = 99.27(6)° with four formula units per unit cell.

Chemie polyfunktioneller Liganden, 69 [1] Über drei Organo-Arsen-Käfigverbindungen mit Noradamantanstruktur / Chemistry of Polyfunctional Ligands, 69 [1] Three Organo-Arsenic Cage Compounds with Noradamantane Structure

1981 ◽  
Vol 36 (12) ◽  
pp. 1532-1537 ◽  
Author(s):  
Jochen Ellermann ◽  
Martin Lietz
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Cage Compounds ◽  
H Nmr ◽  
New Compounds

Abstract The reaction of l.l.l-tris(diiodarsinomethyl)ethane, CH3C(CH2Asl2)3 (1), with H2C(COOC2H5)2, H2C(COOCH3)2 and H2C(COC6H5)2 in presence of the auxiliary base (C2H5)3N gives the noradamantane structured compounds CH3C(CH2As)3E2 [E=C(COOC2H 5)2 (2), C(COOCH3)2 (3) and C(COC6H5)2 (4)].The new compounds have been characterized by mass spectrometry and infrared, Raman and 1H NMR spectroscopy.

tert-Butylimino-δ-Organovanadium(V)-Verbindungen Darstellung und NMR-spektroskopische Untersuchungen/tert-Butylimino-δ-Organovanadium (V) Compounds Synthesis and NMR Spectroscopic Studies

1986 ◽  
Vol 41 (2) ◽  
pp. 185-190 ◽  
Author(s):  
Fritz Preuss ◽  
Flarald Becker
Keyword(s):  
Nmr Spectroscopy ◽  
Nmr Spectra ◽  
Spectroscopic Studies

The compounds tC4H9N=VR(OtC4H9)2 (R = CH3, nC4H9, CH2SiMe3, Mes) and tC4H9N = VMes2(OtC4H9) have been prepared by reaction of tert-butyliminovanadium (V) chlorides with LiR; tC4H9N=V(CH2SiMe3)2(OtC4H9) and tC4H9N=VR3 (R = CH2SiMe3, Mes) could only be characterized by NMR spectroscopy. The 1H, 13C and 51V NMR spectra are discussed; the constants of 51V , 14N coupling have been determined.

Isolation and identification of two new compounds from the Penicillium sp. SYPF7381

2019 ◽  
Vol 34 (14) ◽  
pp. 2007-2013
Author(s):  
Qing-Mei Feng ◽  
Xing-Yu Li ◽  
Bing-Xin Li ◽  
Tian-Yuan Zhang ◽  
Hai-Feng Wang ◽  
...  
Keyword(s):  
Isolation And Identification ◽  
Penicillium Sp ◽  
New Compounds

Compounds of Complex Halo and Pseudohalo Acids of the Group IIB Metals, Part V [1] Preparative and Spectroscopic Studies of the [Hg2I5]-, [Hg2I6]2- and [Hg3I8]2- Ions

1982 ◽  
Vol 37 (5) ◽  
pp. 646-648 ◽  
Author(s):  
S. P. Perlepes ◽  
Th. F. Zafiropoulos ◽  
A. K. Anagnostopoulos ◽  
A. G. Galinos
Keyword(s):  
Solid State ◽  
Spectroscopic Studies ◽  
Molar Conductance ◽  
X Ray ◽  
New Compounds ◽  
Complex Anions

The preparations of new compounds, containing the complex anions [Hg2l5]-, [Hg2l6]2- and [Hg3I8]2-, are reported.Distorted iodine-bridged configurations are proposed for the complexes in the solid state, utilising analyses, X-ray powder patterns, molar conductance measurements and spectral (IR, UV) data

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