A New Bioactive Steroidal Saponin from Agave brittoniana
2007 ◽
Vol 62
(9)
◽
pp. 1193-1198
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Keyword(s):
2D Nmr
◽
A new bisdesmosidic furostanol saponin was isolated from leaves of Agave brittoniana Trel. Its structure was established as 3-[O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β -D-glucopyranosyl-( 1→3)-O]-[O-β -D-glucopyranosyl-(1→3)-β -D-glucopyranosyl-(1→2)-O-β -D-glucopyranosyl- (1→4)-β -D-galactopyranosyl)oxy]-(3β ,5α,6α,22α,2R)-26-(β -D-glucopyranosyloxy)-6,22-dihydroxy- furost-12-one. Its structural identification was performed using detailed analyses of 1H and 13C NMR spectra including 2D NMR spectroscopic techniques (DEPT, COSY, HETCOR and COLOC) and chemical conversions. The steroidal saponin showed no haemolytic effects in the in vitro assays and demonstrated antiinflammatory activity using in vivo models.
2005 ◽
Vol 60
(1-2)
◽
pp. 57-62
◽
2002 ◽
Vol 57
(5-6)
◽
pp. 423-428
◽
2011 ◽
Vol 1
(1)
◽
pp. 031-040
◽
2020 ◽
Vol 21
(5)
◽
pp. 1791
◽
Keyword(s):