Small-molecule inhibitors of histone deacetylase for the treatment of cancer and non-cancer diseases: a patent review (2011 – 2013)

2014 ◽  
Vol 24 (4) ◽  
pp. 401-415 ◽  
Author(s):  
Sergio Valente ◽  
Antonello Mai
Keyword(s):  
Histone Deacetylase ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Patent Review ◽  
Cancer Diseases

scholarly journals PET Imaging Demonstrates Histone Deacetylase Target Engagement and Clarifies Brain Penetrance of Known and Novel Small Molecule Inhibitors in Rat

2014 ◽  
Vol 5 (10) ◽  
pp. 1055-1062 ◽  
Author(s):  
F. A. Schroeder ◽  
C. Wang ◽  
G. C. Van de Bittner ◽  
R. Neelamegam ◽  
W. R. Takakura ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Small Molecule ◽  
Pet Imaging ◽  
Small Molecule Inhibitors ◽  
Target Engagement

Design and synthesis of imidazole based zinc binding groups as novel small molecule inhibitors targeting Histone deacetylase enzymes in lung cancer

2020 ◽  
Vol 1214 ◽  
pp. 128177 ◽  
Author(s):  
Saravanan Kandasamy ◽  
Prabhu Subramani ◽  
Kannupal Srinivasan ◽  
John marshal Jayaraj ◽  
Gunasekaran Prasanth ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Histone Deacetylase ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Zinc Binding ◽  
Design And Synthesis

Small-molecule inhibitors of hepatitis C virus (HCV) non-structural protein 5A (NS5A): a patent review (2010-2015)

2017 ◽  
Vol 27 (4) ◽  
pp. 401-414 ◽  
Author(s):  
Yan A. Ivanenkov ◽  
Vladimir A. Aladinskiy ◽  
Nikolay A. Bushkov ◽  
Andrey A. Ayginin ◽  
Alexander G. Majouga ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Structural Protein ◽  
Patent Review

scholarly journals Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase fromPlasmodium falciparum

2009 ◽  
Vol 52 (8) ◽  
pp. 2185-2187 ◽  
Author(s):  
Vishal Patel ◽  
Ralph Mazitschek ◽  
Bradley Coleman ◽  
Cokey Nguyen ◽  
Sameer Urgaonkar ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Class I ◽  
Identification And Characterization
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