The role of IGF-1 resistance in obesity and type 2 diabetes-mellitus-related insulin resistance and vascular disease

2010 ◽  
Vol 14 (12) ◽  
pp. 1333-1342 ◽  
Author(s):  
Victoria K Gatenby ◽  
Mark T Kearney
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Vascular Disease

scholarly journals Predictors of Insulin Resistance in Obesity and Type 2 Diabetes Mellitus - The Role of Magnesium

2017 ◽  
Vol 06 (04) ◽  
Author(s):  
Soetkin Milbouw ◽  
Julie Verhaegen ◽  
An Verrijken ◽  
Benedicte Y De Winter ◽  
Luc F Van Gaal ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus

scholarly journals Vascular Disease in Diabetic Women: Why Do They Miss the Female Protection?

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Ana Paula Villela Dantas ◽  
Zuleica Bruno Fortes ◽  
Maria Helena Catelli de Carvalho
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Type 2 Diabetes Mellitus ◽  
Vascular Disease ◽  
Vascular Dysfunction ◽  
Protective Effects ◽  
Vascular Protection

Gender plays a pivotal role in the onset as well as in the progression of the cardiovascular disease with a higher morbidity and mortality being detected in men with respect to women. Type 2 Diabetes Mellitus (T2DM) may reduce gender-related differences in the prevalence of cardiovascular disease by fading the vascular protective effects afforded by estrogen in females. This article will discuss the role of sex and sex hormones on the incidence and mechanisms involved in vascular dysfunction associated to T2DM, which might explain why women with T2DM lack the vascular protection.

scholarly journals The role of the lipotoxicity in the pathogenesis of type 2 diabetes mellitus and obesity

2014 ◽  
Vol 11 (2) ◽  
pp. 8-12 ◽  
Author(s):  
F R Abdulkadirova ◽  
A S Ametov ◽  
E V Doskina ◽  
R A Pokrovskaya
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Fatty Acids ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Mellitus Type 2 ◽  
Comorbid Conditions ◽  
Fatty Acids Metabolism

Obesity is a major risk factor for diabetes mellitus type 2, cardiovascular diseases and associated comorbid conditions. It is traditionally considered that insulin resistance is dependent on glucose metabolism. However, in recent years more and more attention is devoted to the fatty acids metabolism, the increase in concentrations of which plays a significant role in the pathophysiological mechanisms associated with insulin resistance.

Role of Interleukin-6 in Development of Insulin Resistance and Type 2 Diabetes Mellitus

2017 ◽  
Vol 27 (3) ◽  
pp. 229-236 ◽  
Author(s):  
Kanwal Rehman ◽  
Muhammad Sajid Hamid Akash ◽  
Aamira Liaqat ◽  
Shagufta Kamal ◽  
Muhammad Imran Qadir ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Interleukin 6

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

2011 ◽  
Vol 8 (2) ◽  
pp. 92-103 ◽  
Author(s):  
Julia Szendroedi ◽  
Esther Phielix ◽  
Michael Roden
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus
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