scholarly journals Prismatic Adaptation Changes Visuospatial Representation in the Inferior Parietal Lobule

2014 ◽  
Vol 34 (35) ◽  
pp. 11803-11811 ◽  
Author(s):  
S. Crottaz-Herbette ◽  
E. Fornari ◽  
S. Clarke
eNeuro ◽  
2017 ◽  
Vol 4 (5) ◽  
pp. ENEURO.0310-17.2017 ◽  
Author(s):  
Sonia Crottaz-Herbette ◽  
Eleonora Fornari ◽  
Isabel Tissieres ◽  
Stephanie Clarke

NeuroImage ◽  
2021 ◽  
Vol 231 ◽  
pp. 117843 ◽  
Author(s):  
Meiqi Niu ◽  
Lucija Rapan ◽  
Thomas Funck ◽  
Seán Froudist-Walsh ◽  
Ling Zhao ◽  
...  

2017 ◽  
Vol 41 (S1) ◽  
pp. S409-S409
Author(s):  
A. Gadad ◽  
D.Y.C.J. Reddy ◽  
D.G. Venkatasubramanian ◽  
D.J. C.N

Aim of the studyTo study the neural substrates of insight in OCD by comparing patients with good insight, patients with poor insight and matched healthy controls using functional MRI.MethodologySubjects were recruited from among patients attending OCD clinic, adult psychiatry services and psychiatry ward inpatients of National Institute of Mental Health And Neurosciences (NIMHANS), Bangalore. They were further divided into ‘good insight’ (n = 30) and ‘poor insight’ (n = 14) using Brown's assessment of belief's scale. Control subjects (n = 30) were recruited from consenting volunteers. 3 T MRI was used mental rotation task was paradigm used for fMRI and analysis was done by SPM 8.ResultsPoor insight patients and good insight patients comparison revealed differential activation in left superior/medial frontal gyrus (corresponding to the DLPFC). A negative correlation between BABS score and activation of right inferior parietal lobule. Mental rotation task behavioural data results: OCD patients as a group had significantly lower accuracy compared to healthy controls. Poor insight group had significantly decreased accuracy ratio compared to good insight group and healthy controls. A negative correlation was noted between BABS score and accuracy ratio, indicating that poorer the insight, greater the errors during the active task.ConclusionInsight has been important prognostic factor in OCD. Poor insight patients had specific deficits in left medial frontal gyrus and right inferior parietal lobule as compared to good insight patients and healthy controls. Together, these indicate that insight has a strong neurobiological underpinning in OCD.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2017 ◽  
Vol 28 (6) ◽  
pp. 2162-2174 ◽  
Author(s):  
Quanjing Chen ◽  
Frank E Garcea ◽  
Robert A Jacobs ◽  
Bradford Z Mahon

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Nirmala Ramalingam ◽  
Barbara Heider ◽  
Anushree P Karnik ◽  
Ralph Mitchell Siegel

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