scholarly journals Single‐cell electrophysiology in macaque inferior parietal lobule during visually guided reach

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Nirmala Ramalingam ◽  
Barbara Heider ◽  
Anushree P Karnik ◽  
Ralph Mitchell Siegel
Keyword(s):  
Single Cell ◽  
Inferior Parietal Lobule ◽  
Visually Guided ◽  
Parietal Lobule

scholarly journals Organization of the macaque monkey inferior parietal lobule based on multimodal receptor architectonics

NeuroImage ◽  
2021 ◽  
Vol 231 ◽  
pp. 117843 ◽  
Author(s):  
Meiqi Niu ◽  
Lucija Rapan ◽  
Thomas Funck ◽  
Seán Froudist-Walsh ◽  
Ling Zhao ◽  
...  
Keyword(s):  
Macaque Monkey ◽  
Inferior Parietal Lobule ◽  
Parietal Lobule

Neuroimaging correlates of insight in obsessive compulsive disorder: A fMRI study

2017 ◽  
Vol 41 (S1) ◽  
pp. S409-S409
Author(s):  
A. Gadad ◽  
D.Y.C.J. Reddy ◽  
D.G. Venkatasubramanian ◽  
D.J. C.N
Keyword(s):  
Mental Rotation ◽  
Negative Correlation ◽  
Mental Rotation Task ◽  
Healthy Controls ◽  
Inferior Parietal Lobule ◽  
Good Insight ◽  
Compulsive Disorder ◽  
Accuracy Ratio ◽  
Parietal Lobule ◽  
Medial Frontal Gyrus

Aim of the studyTo study the neural substrates of insight in OCD by comparing patients with good insight, patients with poor insight and matched healthy controls using functional MRI.MethodologySubjects were recruited from among patients attending OCD clinic, adult psychiatry services and psychiatry ward inpatients of National Institute of Mental Health And Neurosciences (NIMHANS), Bangalore. They were further divided into ‘good insight’ (n = 30) and ‘poor insight’ (n = 14) using Brown's assessment of belief's scale. Control subjects (n = 30) were recruited from consenting volunteers. 3 T MRI was used mental rotation task was paradigm used for fMRI and analysis was done by SPM 8.ResultsPoor insight patients and good insight patients comparison revealed differential activation in left superior/medial frontal gyrus (corresponding to the DLPFC). A negative correlation between BABS score and activation of right inferior parietal lobule. Mental rotation task behavioural data results: OCD patients as a group had significantly lower accuracy compared to healthy controls. Poor insight group had significantly decreased accuracy ratio compared to good insight group and healthy controls. A negative correlation was noted between BABS score and accuracy ratio, indicating that poorer the insight, greater the errors during the active task.ConclusionInsight has been important prognostic factor in OCD. Poor insight patients had specific deficits in left medial frontal gyrus and right inferior parietal lobule as compared to good insight patients and healthy controls. Together, these indicate that insight has a strong neurobiological underpinning in OCD.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Abstract Representations of Object-Directed Action in the Left Inferior Parietal Lobule

2017 ◽  
Vol 28 (6) ◽  
pp. 2162-2174 ◽  
Author(s):  
Quanjing Chen ◽  
Frank E Garcea ◽  
Robert A Jacobs ◽  
Bradford Z Mahon
Keyword(s):  
Inferior Parietal Lobule ◽  
Abstract Representations ◽  
Directed Action ◽  
Parietal Lobule

scholarly journals Effect of tDCS over the Right Inferior Parietal Lobule on Mind-Wandering Propensity

2020 ◽  
Author(s):  
Sean Coulborn ◽  
Howard Bowman ◽  
Chris Miall ◽  
Davinia Fernández-Espejo
Keyword(s):  
Mind Wandering ◽  
Inferior Parietal Lobule ◽  
Double Blind ◽  
Default Mode ◽  
Dorsolateral Prefrontal ◽  
Parietal Lobule ◽  
Response Task ◽  
Thought Probes ◽  
The Right ◽  
Subjective Reports

Mind-wandering is associated with switching our attention to internally directed thoughts and is by definition an intrinsic, self-generated cognitive function. Interestingly, previous research showed that it may be possible to modulate its propensity externally, with transcranial direct current stimulation (tDCS) targeting different regions in the default mode and executive control networks. However, these studies used highly heterogeneous montages (targeting the dorsolateral prefrontal cortex (DLPFC), the right inferior parietal lobule (IPL), or both concurrently), often showed contradicting results, and in many cases failed to replicate. Our study aimed to establish whether tDCS of the default mode network, via targeting the right IPL alone, could modulate mind-wandering propensity using a within-subjects double-blind, counterbalanced design. Participants completed a sustained attention to response task (SART) interspersed with thought-probes to capture their subjective reports of mind-wandering before and after receiving anodal, cathodal, or sham tDCS over the right IPL (with the reference over the left cheek). We found evidence for the lack of an effect of stimulation on subjective reports of mind-wandering (JZS-BF01 = 5.19), as well as on performance on the SART task (errors (JZS-BF01 = 6.79) and reaction time (JZS-BF01 = 5.94). Overall, we failed to replicate previous reports of successful modulations of mind-wandering propensity with tDCS over the IPL, instead providing evidence in support of the lack of an effect. This, and other recent unsuccessful replications call into question whether it is indeed possible to externally modulate spontaneous or self-generated cognitive processes.

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