scholarly journals A Simple Simulation of Surface Plasmon Resonance in The Kretschmann Configuration Using Google Sheets

2020 ◽  
Vol 16 (2) ◽  
pp. 83-91
Author(s):  
N. K. Quang ◽  
N. P. Q. Anh ◽  
H. C. Hieu

This article describes a simple numerical simulation of three-layer surface plasmon resonance (SPR) in the Kretschmann configuration. The calculation was performed in Google Sheets, a web-based spreadsheet environment that functions similarly to Microsoft Excel where it is easily accessible for students via the internet. Specifically, Fresnel’s equations were utilized to calculate the intensity of the reflected light for the p-polarized incident light on a three-layer system. The complex functions were utilized to plot the SPR curves. We examined the change of the resonance angle by the influence of the incident wavelength. The simulation was also performed for different thicknesses of the gold film layer. To demonstrate the sensitivity, we obtained the SPR curves with the variation of the refractive index in the sensitive medium. The SPR accuracy was analysed by comparing our obtained result with the published work. It is intended to incorporate into undergraduate instrumental analysis courses.

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Nusrat Alim ◽  
Mohammad Nasir Uddin

In this study, a planar D-shape optical fiber sensor based on Surface Plasmon Resonance phenomenon using two different excitation methods has been demonstrated. The proposed bio-sensor uses Amplitude-Wavelength hybrid detection technique to determine the change in urine refractive index that depends on resonance parameters. The analysis employs finite element method to investigate the optical properties of the proposed sensor. From the results it can be evident that Otto configuration offers greater amount of reflected light intensity dip for a particular urine refractive index in comparison with Kretschmann configuration. For an example, for Otto configuration the dip of reflected light intensity measured in terms of reflectance which attains a value 0.5 for ns (urine refractive index) of 1.489 while Kretschmann configuration provides a dip of 0.65 for the same value of ns. Results also show that the sharpness of reflectance is comparatively higher for the sensor using Otto configuration in comparison with Kretschmann configuration in case of wavelength interrogation. Thus, Otto configuration offers better performance in comparison with Kretschmann configuration.


2016 ◽  
Vol 122 (4) ◽  
Author(s):  
Jiří Bulíř ◽  
Tomáš Zikmund ◽  
Michal Novotný ◽  
Ján Lančok ◽  
Ladislav Fekete ◽  
...  

2015 ◽  
Vol 4 (1) ◽  
pp. 77-83 ◽  
Author(s):  
A. Henseleit ◽  
C. Pohl ◽  
Th. Bley ◽  
E. Boschke

Abstract. Continuously monitoring cell cultures is essential for both controlling critical parameters and improving understanding of key processes. An ideal technique in this context is surface plasmon resonance (SPR) spectroscopy, which essentially exploits changes in the angle of incident light that occur when molecules bind to a surface. It provides the ability to monitor real-time changes in small concentrations of various molecules, with no need for additional labels or sample preparation. Here we present an SPR-based immunoassay for monitoring concentrations of human serum albumin (HSA), and compare its sensitivity when used in conjunction with a Biacore platform and the cheaper, smaller liSPR system. In conjunction with either system, the immunoassay can detect HSA (a hepatocyte viability marker) at concentrations typically present in three-dimensional hepatocyte cultures mimicking the liver used to evaluate effects of drug candidates before exposure to humans or animals. Furthermore, in conjunction with the liSPR system, it is sufficiently sensitive to measure the much lower HSA levels present in skin–hepatocyte co-cultures.


2020 ◽  
Vol 2 (1) ◽  
pp. 10-17
Author(s):  
Nidaa AL-Janaby ◽  
Anwaar AL-Dergazly

During   this work, fiber optic sensor based on surface Plasmon resonance (SPR) was prepared. The sensor of SPR was configured by coating a thin layer of gold film on the end of a cleaved optical fiber by a sputtering technique.  The source of white light   was utilized to produce a series   of wavelengths and excites surface Plasmon resonance at the fiber tip. SPR sensor was immersed into media with different refractive indexes in the range )1-1.58( including their similar Plasmon resonance wavelength shifts were saved by optical spectrum analyzer and noticed reflected light on a personal computer. Experimental results that obtained show there is a redshift when increasing the refractive index of solutions and sensitivity reach 298nm/ RIU, and resolution 4.31x .


Plasmonics ◽  
2016 ◽  
Vol 12 (3) ◽  
pp. 707-715 ◽  
Author(s):  
Yuzhi Chen ◽  
Xuejin Li ◽  
Huasheng Zhou ◽  
Qingli Xie ◽  
Xueming Hong ◽  
...  

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