scholarly journals The Analgesic Effects of Bupivacaine and Magnesium Sulfate Combination, Bupivacaine, and Adrenaline Combination and Bupivacaine Alone on Post-cesarean Section Pain: A Randomized Clinical Trial

2018 ◽  
Vol 9 (4) ◽  
pp. 284-290
Author(s):  
Zinatossadat Bouzari ◽  
Seyedeh Rabeeh Rouhani ◽  
Ebrahim Alijanpour ◽  
Shahla Yazdani ◽  
Bahman Hasannasab ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Magnesium Sulfate ◽  
Randomized Clinical Trial ◽  
Normal Saline ◽  
Repeated Measures ◽  
The Other ◽  
Hemodynamic Parameters ◽  
Analgesic Effects ◽  
Single Blind

Objectives: The present study was performed to compare the analgesic effects of bupivacaine and magnesium sulfate combination on post-cesarean (C) section pain. Materials and Methods: The present single-blind randomized clinical trial was conducted on 160 C-section candidates. The participants were randomly divided into four groups. When the fascia healed, the first group received 20 mL of 0.25% bupivacaine and the second group received 20 mL of 0.25% bupivacaine combined with subcutaneous adrenaline. In addition, both groups received 50 mL of intravenous normal saline. Further, the third group received subcutaneous bupivacaine and 50 mg/kg of magnesium sulfate and the fourth group received subcutaneous and intravenous normal saline as a placebo. The pain intensity was assessed 2, 6, 12, 18, and 24 hours after spinal anesthesia using the visual analogue scale (VAS) for pain. The dose of pethidine (as a standard analgesic) and hemodynamic parameters (i.e., heart rate [HR] and blood pressure [BP]) was recorded as well. The obtained data were then analyzed utilizing ANOVA, Tukey’s HSD, and repeated measures ANOVA tests. Results: The intensity of pain and the dose of pethidine decreased significantly in the combination of bupivacaine with magnesium compared to the other groups at all times (P < 0.001). However, diastolic BP significantly increased in the bupivacaine + adrenaline group in comparison with the other groups (P = 0.02). Conclusions: Overall, bupivacaine combination with magnesium sulfate is suitable for controlling post-cesarean section pain.

Impact of inhalation aromatherapy with Damask Rose (Rosa damascena) on stress, anxiety and hemodynamic parameters of patients undergoing coronary angiography: a single blind randomized clinical trial

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Ali Bikmoradi ◽  
Ghodratollah Roshanaei ◽  
Shirin Moradkhani ◽  
Azad Fatahi
Keyword(s):  
Clinical Trial ◽  
Coronary Angiography ◽  
Randomized Clinical Trial ◽  
Control Group ◽  
Rosa Damascena ◽  
Hemodynamic Parameters ◽  
Coronary Artery Angiography ◽  
Before And After ◽  
And Control ◽  
Single Blind

Abstract Objectives Coronary arteries angiography is used commonly for diagnosing cardiovascular diseases. In spite of the low risk of coronary artery angiography method, it could lead to stress, anxiety and consequently hemodynamic changes in patients. This study aimed to assess the effects of inhalation aromatherapy with Rosa damascena on stress, anxiety, and hemodynamic parameters of patients undergoing coronary angiography. Methods A single-blind randomized clinical trial was conducted on 98 patients in Besat Educational Hospital, Hamadan, Iran. Before coronary angiography, patients at aromatherapy group inhaled five drops of 40% Rosa damascena for 20 min and in the control group, patients inhaled distilled water. Stress, anxiety, and hemodynamic parameters were measured before and after the intervention using DASS-21 questionnaire and checklist. Results Data were analysed by SPSS 16 software using descriptive and inferential statistics such as paired t-test and non-parametric tests. There were significant differences in terms of stress and anxiety severity in patients at aromatherapy group (p=0.005) and control group (p=0.001). There were significant differences in terms of hemodynamic parameters such as heart rate (p=0.001), mean arterial pressure (p=0.001), systolic (p=0.003) and diastolic blood pressure (p=0.001) and SpO2 (p=0.02). Conclusions Inhalation aromatherapy with Rosa damascena can significantly decrease stress and anxiety severity and improve hemodynamic parameters of patients undergoing coronary angiography. Registry number This study has registered with the number IRCT201702019759N8 at Iranian Registry Clinical Trial.

scholarly journals Magnesium Sulfate versus Placebo for Paroxysmal Atrial Fibrillation: A Randomized Clinical Trial

2009 ◽  
Vol 16 (4) ◽  
pp. 295-300 ◽  
Author(s):  
Kevin Chu ◽  
Rhona Evans ◽  
Gregory Emerson ◽  
Jaimi Greenslade ◽  
Anthony Brown
Keyword(s):  
Atrial Fibrillation ◽  
Clinical Trial ◽  
Magnesium Sulfate ◽  
Randomized Clinical Trial ◽  
Paroxysmal Atrial Fibrillation

scholarly journals Sufentanil in combination with low-dose hyperbaric bupivacaine in spinal anesthesia for cesarean section: a randomized clinical trial

2016 ◽  
Vol 66 (6) ◽  
pp. 622-627 ◽  
Author(s):  
Alexandre Dubeux Dourado ◽  
Ruy Leite de Melo Lins Filho ◽  
Raphaella Amanda Maria Leite Fernandes ◽  
Marcelo Cavalcanti de Sá Gondim ◽  
Emmanuel Victor Magalhães Nogueira
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Randomized Clinical Trial ◽  
Low Dose ◽  
Hyperbaric Bupivacaine

scholarly journals Auriculotherapy to reduce anxiety and pain in nursing professionals: a randomized clinical trial

2017 ◽  
Vol 25 (0) ◽  
Author(s):  
Leonice Fumiko Sato Kurebayashi ◽  
Ruth Natalia Teresa Turrini ◽  
Talita Pavarini Borges de Souza ◽  
Carolina Felicio Marques ◽  
Renata Tavares Franco Rodrigues ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Nursing Staff ◽  
Repeated Measures ◽  
Statistical Significance ◽  
Cohen’S D ◽  
Pain Visual Analog Scale ◽  
Cohen's D

RESUMEN Objectives: to evaluate the effectiveness of the auricular protocol (APPA) in reducing pain and anxiety and improving the quality of life of the nursing staff of a hospital. Method: randomized clinical trial with an initial sample of 180 professionals divided into 4 groups Control (G1), Seed (G2), Needle (G3) and Tape (G4). The evaluation instruments were the State-Trait Anxiety Inventory, Pain Visual Analog Scale and Quality of Life instrument, applied at the start and after five and 10 sessions (five weeks). Descriptive statistics, analysis of variance (ANOVA) and Cohen's d Index were used in the analysis. Results: there was a statistical difference (p < 0.05) for anxiety according to the repeated measures ANOVA, with better results for the G3 in the final assessment (Cohen's d index 1.08/17% reduction). There was a reduction of pain of 36% in G3 and 24% in G2 and a 13% increase in the mental aspect of quality of life for the G3, although without statistical significance. Conclusion: the APPA protocol reduced the anxiety levels of nursing staff after 10 sessions. Further studies are, however, suggested with new populations and in different contexts so that the results can be confirmed. RBR-5pc43m.

scholarly journals Spinal anesthesia for elective cesarean section. Bupivacaine associated with different doses of fentanyl. Randomized clinical trial

2021 ◽  
Author(s):  
Wesla Packer Pfeifer Ferrarezi ◽  
Angélica de Fátima de Assunção Braga ◽  
Valdir Batista Ferreira ◽  
Sara Quinta Mendes ◽  
Maria José Nascimento Brandão ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Randomized Clinical Trial ◽  
Elective Cesarean Section ◽  
Elective Cesarean ◽  
Different Doses
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