scholarly journals Thyroid dysfunction during pregnancy and in the first postpartum year in women with diabetes mellitus type 1

2002 ◽  
pp. 443-451 ◽  
Author(s):  
PR Gallas ◽  
RP Stolk ◽  
K Bakker ◽  
E Endert ◽  
WM Wiersinga
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Thyroid Dysfunction ◽  
Well Being ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Psychomotor Development ◽  
Thyroid Peroxidase ◽  
In Pregnancy

BACKGROUND: The prevalence of thyroid dysfunction in pregnancy and in the first postpartum year (postpartum thyroid dysfunction (PPTD)) in women with diabetes mellitus type 1 (DM1) is known to be higher than in the general population. To assess prevalence, incidence and risk factors in The Netherlands we performed a prospective cohort study. DESIGN: From 1994 to 1998, 126 women with DM1 from eight Dutch clinics were included. TSH, free thyroxine, free tri-iodothyronine and anti-thyroid peroxidase antibodies (TPO-ab) were measured pre-pregnancy, in the first and last trimester of pregnancy and at 1.5, 3, 6, 9 and 12 months after delivery. RESULTS: Eighty-two women completed the study. Thyroid dysfunction during pregnancy was observed in 22.5% (first trimester) and 18.4% (third trimester), and mostly consisted of subclinical hypothyroidism. Baseline characteristics of women with thyroid dysfunction in pregnancy did not differ from those without thyroid dysfunction. Overt PPTD was seen in 15.9%. Incidence of PPTD was 10%. Patients with PPTD were slightly older than those without PPTD and the prevalence of TPO-ab was higher in these women. CONCLUSION: In women with DM1 the prevalence of thyroid dysfunction during pregnancy and overt PPTD is 3-fold higher than in the general Dutch population. Risk factors are age and TPO-ab. Given the possible impact on psychomotor development of the offspring and on well-being of the mother these data suggest there is a case for screening (pre-)pregnant women with DM1 for TSH and TPO-ab.

scholarly journals Seroprevalence, risk factors and comorbidities associated with Helicobacter pylori infection amongst children receiving care at Kilimanjaro Christian Medical Center

1970 ◽  
Vol 19 (4) ◽  
pp. 3208-3216
Author(s):  
Amos Msekandiana ◽  
Levina Msuya ◽  
Rune Philemon ◽  
Blandina M'mbaga ◽  
Grace Kinabo
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Helicobacter Pylori ◽  
Tap Water ◽  
Diabetes Mellitus Type 1 ◽  
Household Size ◽  
Diabetes Mellitus Type ◽  
Age Group ◽  
H Pylori

Background: Helicobacter pylori frequently causes gastritis and peptic ulcers, and affected children are at risk of developing gastric carcinoma later in adulthood.Methods: This was a Hospital based cross sectional study. A total of 200 children aged 6 months to 14 years were enrolled. Study subjects were tested for H. pylori using a standard serology rapid test measuring immunoglobulin G for H. pylori. For risk factors, Chi-square tests were used to test for association and then, odds ratios and their corresponding 95% confidence intervals and p-values were computed using logistic regression.Results: The overall seroprevalence of H. pylori was 11.5%. The following factors were associated with H. pylori infection: Age group above 10 years, keeping a dog and household size. The independent predictors of H. pylori were: Fathers’ occupation, keeping a dog, indoor tap water, age group, household size and diabetes mellitus type 1.Conclusion: The seroprevalence of H. pylori antibodies was lower compared to most developing countries. Keeping a dog, household size, indoor tap water, fathers’ occupation and diabetes mellitus type 1 were found to be independent predictors of presence of H. pylori antibodies.Keywords: Helicobacter Pylori.

scholarly journals ASSOCIATION OF DIABETES IN PREGNANCY WITH THYROID DYSFUNCTION AND AUTOIMMUNITY

2021 ◽  
pp. 1-3
Author(s):  
Ekta Kanojia ◽  
Suman Lata Mendiratta ◽  
Vineeta Sarbhai
Keyword(s):  
Diabetes Mellitus ◽  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Tertiary Care ◽  
Overt Hypothyroidism ◽  
Thyroid Peroxidase ◽  
Diabetes In Pregnancy ◽  
Type 1 Dm ◽  
In Pregnancy

PURPOSE This study was undertaken to find out the proportion of women with diabetes in pregnancy complicated by thyroid dysfunction compared to non-diabetic pregnant women. To find out the association, if any, of thyroid dysfunction and anti-thyroid peroxidase (anti-TPO) antibodies during pregnancy with type1 diabetes mellitus, type 2 diabetes mellitus, gestational diabetes mellitus (GDM) and non-diabetic pregnant women. METHODS A cross-sectional observational study was conducted in a tertiary care teaching hospital in New Delhi, India, for a period of one year. 100 women with diabetes in pregnancy and 100 non-diabetic pregnant women were recruited from the ante-natal clinic. The women were evaluated for thyroid dysfunction, thyroid autoimmunity and were managed according to the hospital’s protocols. The relevant data were recorded and statistical analysis was done. RESULTS 24% of women with diabetes in pregnancy and 8% of non-diabetic women had hypothyroidism. Subclinical hypothyroidism was most prevalent in women with GDM (15.25%) and overt hypothyroidism was most prevalent in women with type 1 DM (28.57%). Mean serum TSH levels were highest in women with type 1 DM. Positive anti-TPO antibodies were significantly associated with diabetes in pregnancy compared to non-diabetic women (p=0.02). Amongst women with diabetes in pregnancy, positive anti-TPO antibodies were significantly associated with type 1 DM (p<0.01) CONCLUSIONS Thyroid disorders are commonly associated with diabetes in pregnancy. The study findings suggest routine screening for thyroid abnormalities in diabetic pregnant women.

Psychological problems in children with diabetes mellitus type 1

2015 ◽  
Author(s):  
Anzhalika Solntsava ◽  
Olga Zagrebaeva ◽  
Nadeya Peskavaya ◽  
Viktoryia Kozel ◽  
Hanna Mikhno
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 1 ◽  
Psychological Problems ◽  
Diabetes Mellitus Type

Seksuele problemen bij vrouwen met diabetes mellitus type 1 en bij een vergelijkbare controlegroep

2002 ◽  
Vol 58 (23) ◽  
pp. 1589-1598
Author(s):  
ENZLIN P ◽  
MATHIEU C ◽  
VAN DEN BRUEL A ◽  
BOSTEELS J ◽  
VANDERSCHUEREN D ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type

Simultaneous Juvenile Idiopathic Arthritis and Diabetes Mellitus Type 1 — A Finnish Nationwide Study

2011 ◽  
Vol 39 (2) ◽  
pp. 377-381 ◽  
Author(s):  
HEINI POHJANKOSKI ◽  
HANNU KAUTIAINEN ◽  
MATTI KORPPI ◽  
ANNELI SAVOLAINEN
Keyword(s):  
Diabetes Mellitus ◽  
Juvenile Idiopathic Arthritis ◽  
Autoimmune Disease ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Laboratory Findings ◽  
Type 1 Dm ◽  
Psychiatric Problems ◽  
Rheumatoid Factor Seropositivity

Objective.To describe the occurrence and main clinical and laboratory findings of patients having both juvenile idiopathic arthritis (JIA) and diabetes mellitus type 1 (DM-1) in a period of 30 years.Methods.Eighty-two patients having simultaneous JIA and DM-1 were identified in the reimbursement registers of the Finnish National Institute of Insurance during the period 1976–2005. Data on their clinical histories were collected from patient files.Results.Occurrence of simultaneous JIA and DM-1 increased 4.5-fold between the first (1976-85) and the last (1996–2005) decade. Prevalence of uveitis was 7%, of rheumatoid factor seropositivity 15%; 22% of patients had a third autoimmune disease [autoimmune disease (AID)], and 16% had serious psychiatric problems.Conclusion.The occurrence of patients with the 2 diseases, JIA and DM-1, increased over 3 decades. The prevalence of uveitis was low, the number of seropositive patients was high, and further cases of AID were frequent. Patients had multiple additional problems necessitating multiprofessional care.

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