Pulmonary metastasis of a pure oncocytic adrenocortical neoplasm after a 2 years follow up

2021 ◽  
Author(s):  
Clothilde Wagner ◽  
Sarah Mansour ◽  
Niculina Racolta ◽  
Philippe Keller ◽  
Pramod Rao ◽  
...  
Keyword(s):  
Pulmonary Metastasis ◽  
Adrenocortical Neoplasm

scholarly journals Simultaneous development of COVID-19 pneumonia and pulmonary metastasis in a known case of chondrosarcoma: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Afshin Rakhsha ◽  
Zahra Mahboubi-Fooladi ◽  
Anya Jafari
Keyword(s):  
Pulmonary Metastasis ◽  
Pulmonary Nodules ◽  
Simultaneous Presentation ◽  
Case Presentation ◽  
History Of ◽  
Polymerase Chain ◽  
Lung Ct ◽  
Chest Ct Scan ◽  
Interlobular Septal Thickening

Abstract Background The outbreak of coronavirus disease 2019 (COVID-19) started in December 2020, and is a global problem now. There are several sets of established data regarding computed tomography (CT) findings in COVID-19 pneumonia with many differential diagnoses. During the early days of the pandemic, there was little data regarding lung CT features of COVID-19 in a cancer patient. In this paper, we described a rare case of simultaneous presentation of COVID-19 with pulmonary metastasis. Case presentation A Persian patient with a history of chondrosarcoma presented to our clinic during the COVID-19 pandemic with a new-onset cough. He had experienced no recurrence during previous follow-up visits. Chest CT scan revealed numerous bilateral small peripheral and perilymphatic pulmonary nodules, unilateral ground-glass patch, and nodular interlobular septal thickening. Biopsy of the pulmonary nodules established pulmonary metastasis of chondrosarcoma origin, and pharyngeal reverse transcription polymerase chain reaction (RT-PCR) was positive for COVID-19. Conclusion Pulmonary metastasis should be considered as a differential diagnosis of COVID-19 features in cancer patients in the pandemic era.

scholarly journals Diferential Diagnosis between Esophageal Granuloma and Pulmonary Metastasis

2018 ◽  
Vol 46 ◽  
pp. 4
Author(s):  
Stéfane Valgas Teixeira ◽  
Fernanda Camargo Nunes ◽  
Gleide Eunice Lavalle ◽  
Rúbia Monteiro de Castro Cunha ◽  
Paula Mayer Costa ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pulmonary Metastasis ◽  
Parasitic Infection ◽  
Biological Behavior ◽  
Clinical Staging ◽  
Malignant Schwannoma ◽  
Spirocerca Lupi ◽  
Oncologic Patients ◽  
History Of

Background: Spirocercosis is a parasitic infection caused by Spirocerca lupi. This pathology affects canid carnivores, especially domestic dogs. Early diagnosis has been proven challenging and most infected animals are diagnosed when disease is in advanced stage. Exams such as computed tomography scans or radiographs can aid in disease confirmation.Radiographic exam frequently reveals the presence of a mass located in mediastinal region, which can be erroneously diagnosed as pulmonary mass. The aim of this study was to report the differential diagnosis between paraesophageal granuloma, possibly due to spirocercosis, and pulmonary metastasis in a dog with a history of neurofibrosarcoma.Case: A 8 year-old male Cocker Spaniel dog, weighing 17.4 kg, was presented with anterior limb suspension and a recurrent nodule of 2.0 cm diameter, located on the main pad, with previous diagnosis of neurofibrosarcoma (malignant Schwannoma). Routine evaluation work-up included thoracic radiographs and abdominal ultrasound for clinical staging, electrocardiogram, complete blood count (CBC), coagulogram, renal and hepatic function tests, with results within the normal range for the species. The dog submitted to left anterior limb amputation due to recurrent neurofibrosarcoma in the carpal region. Histopathological exam confirmed recurrent neurofibrosarcoma without vascular invasion. Considering neoplasm biological behavior and clean surgical margins, only routine follow-up was established, with clinical exams. The dogwas presented to the Veterinary Hospital five months after surgical treatment and it was presented with fever, prostration, and history of vomiting. Radiographic exam showed a circumscribed mass in caudal mediastinal area. Computed tomography scan was performed to best evaluate the mass and the result was compatible with paraesophageal abscess. These findings were consistent with paraesophageal abscess with necrotic center caused by Spirocerca lupi; however, it was not possible to exclude the possibility of lymph node neoplasms, with necrotic center/secondary abscess. Coproparasitological test result was negative; however, considering the endemic aspect of spirocercosis, the dog was treated with Ivermectin was given orally, for 14 days, and complete remission was observed at the end of the treatment, without any significant side effects.Discussion: Spirocercosis has a worldwide dissemination, limited only by the presence of intermediate host. In endemic regions, prevalence in dogs may be 100%. Diagnosis may be challenging, especially in atypical cases and in patients with complications. Spirocercosis diagnosis may be achieved from therapeutic response in typical cases, with suggestiveradiographic and tomographic findings. Radiologic and tomographic findings in this case were similar to common spirocercosis findings. Follow up by a veterinary oncologist is of utmost importance; an unprepared veterinarian could indicate thoracotomy or even euthanasia. Even though coproparasitological exam was negative, the endemic aspect of spirocercosis in the area supported the decision for treatment and therapeutic diagnosis. Oncologic patients should be carefully evaluated,for not all pathologies they develop after a neoplasm diagnosis are related to cancer. Knowledge of disease biologic behavior is essential to make correct decisions regarding patient health status.Keywords: Spirocerca lupi, granulomas, neurofibrosarcoma.

scholarly journals Chromosomal Abnormalities Associated With Local Recurrence or Pulmonary Metastasis of Giant Cell Tumor of Bone in Thai Adults: A Prospective Cohort Study With 6 Years of Follow-Up

2021 ◽  
Author(s):  
Pakpoom Ruangsomboon ◽  
Worapa Heepchantree ◽  
Pissanu Reingrittha ◽  
Saranatra Waikakul ◽  
Rapin Phimolsarnti
Keyword(s):  
Cohort Study ◽  
Local Recurrence ◽  
Giant Cell Tumor ◽  
Pulmonary Metastasis ◽  
Cytogenetic Analysis ◽  
Chromosomal Abnormalities ◽  
Cell Tumor ◽  
Abnormal Cells ◽  
The Mean

Abstract Background: Giant cell tumor (GCT) of bone demonstrates chromosomal abnormalities. This study aimed to investigate the prognostic role of chromosomal abnormalities of primary GCT of bone relative to local recurrence or pulmonary metastasis.Methods: This prospective longitudinal cohort study with 6 years of follow-up included consecutive patients with primary GCT of bone that were surgically treated during 2011 to 2013 at the Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. All patients underwent surgical resection with extended intralesional curettage and phenol local adjuvant therapy. Systematic cytogenetic analysis compared cytogenetic abnormalities between patients with and without local recurrence or pulmonary metastasis. Fifteen patients were eligible, enrolled, and had successful cytogenetic analysis.Results: The median follow-up time was 46 months (interquartile range [IQR]: 32-58). Five patients experienced local recurrence or pulmonary metastasis with a median time to recurrence of 6 months (IQR: 3.25-10.5). The mean number of abnormal cells in the primary culture compared between those with local recurrence or pulmonary metastasis and those without was 24.4 vs. 9.6 cells, respectively (p=0.04). A similar pattern was observed in the cultures of the subsequent four passages (all p<0.05). Forty-five patterns of clonal telomeric association (tas) were observed in passaged cultures. Six tas patterns were associated with local recurrence or pulmonary metastasis, including tas(11;19)(p15;q13.4), tas(15;19)(q26.3;q13.4), tas(15;22)(p13;p13), tas(16;19)(p13.3;q13.4), tas(17;19)(p13;q13.4), and tas(19;22)(q13.4;q13).Conclusions: The mean number of abnormal cells and the six identified TAS patterns may be valuable prognostic factors for local recurrence or pulmonary metastasis of GCT tumor of bone.

scholarly journals Pulmonary Metastasis from Pseudomyxoma Peritonei

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Toshiyuki Kitai
Keyword(s):  
Pulmonary Metastasis ◽  
Pseudomyxoma Peritonei ◽  
Clinical Findings ◽  
Therapeutic Modality ◽  
Locoregional Therapy ◽  
Rapid Progression ◽  
Low Grade ◽  
Abdominal Lesions ◽  
Disease Free

Pseudomyxoma peritonei (PMP) is a rare clinical condition, where copious mucinous ascites accumulate in the peritoneal cavity due to dissemination of mucin-producing tumor. Because of this disseminating, yet nonmetastasizing, behavior, PMP attracts much interest from surgical oncologists in that aggressive locoregional therapy can give the opportunity of long survival and even cure. Although extra-abdominal metastasis is exceptionally rare, the lung is the most likely site in such a case. In this paper, the clinical findings and treatment of eleven cases with pulmonary metastasis from PMP were reviewed, including ten cases in the literature and one case which we experienced. The clinical features of PMP cases with pulmonary metastasis were similar to cases without pulmonary metastasis. The histological type was low-grade mucinous neoplasm in most cases. Pulmonary lesions were resected in seven cases in which abdominal lesions were controlled by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy or another therapeutic modality. Disease-free state was maintained in five cases at the end of the follow-up period. However, it should be noted that rapid progression after resection was seen in two cases, suggesting that biological features may have changed by surgical intervention.

Epithelioid angiomyolipoma with skeletal and pulmonary metastasis on 8 year follow-up

Pathology ◽  
2010 ◽  
Vol 42 (6) ◽  
pp. 591-594 ◽  
Author(s):  
Czar Louie L. Gaston ◽  
John Slavin ◽  
Michael Henderson ◽  
Peter F.M. Choong
Keyword(s):  
Pulmonary Metastasis ◽  
Epithelioid Angiomyolipoma

scholarly journals Introducing a New Term: Metastasoptysis- A Case Report

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Sercan Aydin
Keyword(s):  
Case Report ◽  
Pulmonary Metastasis ◽  
Colon Adenocarcinoma ◽  
Rare Condition ◽  
Metastatic Tumor ◽  
Colorectal Carcinomas ◽  
Primary Malignancy

Pulmonary metastasis is not uncommon in the follow-up of patients with primary malignancy, but the expectoration of metastatic tumor is extremely rare. Metastases from renal and breast malignities may rarely lead to tumor expectoration with less common colorectal carcinomas. In this case report, expectoration of a metastatic tumor in a patient who had diagnosed with colon adenocarcinoma and pulmonary metastasis was presented. We named this quite rare condition as “metastasoptysis”.

scholarly journals Resection of hepatic and pulmonary metastasis from metastatic esophageal and gastric cancer: a nationwide study

2019 ◽  
Vol 32 (12) ◽  
Author(s):  
M F J Seesing ◽  
A van der Veen ◽  
H J F Brenkman ◽  
H B A C Stockmann ◽  
G A P Nieuwenhuijzen ◽  
...  
Keyword(s):  
Pulmonary Metastasis ◽  
Pulmonary Metastases ◽  
Hepatic Metastases ◽  
Standard Of Care ◽  
Best Supportive Care ◽  
National Registry ◽  
Gastroesophageal Cancer ◽  
Curative Intent ◽  
The Individual

SUMMARY The standard of care for gastroesophageal cancer patients with hepatic or pulmonary metastases is best supportive care or palliative chemotherapy. Occasionally, patients can be selected for curative treatment instead. This study aimed to evaluate patients who underwent a resection of hepatic or pulmonary metastasis with curative intent. The Dutch national registry for histo- and cytopathology was used to identify these patients. Data were retrieved from the individual patient files. Kaplan–Meier survival analysis was performed. Between 1991 and 2016, 32,057 patients received a gastrectomy or esophagectomy for gastroesophageal cancer in the Netherlands. Of these patients, 34 selected patients received a resection of hepatic metastasis (n = 19) or pulmonary metastasis (n = 15) in 21 different hospitals. Only 4 patients received neoadjuvant therapy before metastasectomy. The majority of patients had solitary, metachronous metastases. After metastasectomy, grade 3 (Clavien–Dindo) complications occurred in 7 patients and mortality in 1 patient. After resection of hepatic metastases, the median potential follow-up time was 54 months. Median overall survival (OS) was 28 months and the 1-, 3-, and 5- year OS was 84%, 41%, and 31%, respectively. After pulmonary metastases resection, the median potential follow-up time was 80 months. The median OS was not reached and the 1-, 3-, and 5- year OS was 67%, 53%, and 53%, respectively. In selected patients with gastroesophageal cancer with hepatic or pulmonary metastases, metastasectomy was performed with limited morbidity and mortality and offered a 5-year OS of 31–53%. Further prospective studies are required.

scholarly journals A novel skin-stretching device for closing large skin-soft tissue defects after soft tissue sarcoma resection

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Qiang Wu ◽  
Zengwu Shao ◽  
Yubin Li ◽  
Saroj Rai ◽  
Min Cui ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Pulmonary Metastasis ◽  
Wound Closure ◽  
Skin Closure ◽  
Soft Tissue Defects ◽  
Skin Stretching ◽  
Large Skin ◽  
Tissue Defects

Abstract Background Closure of large skin-soft tissue defects following soft tissue sarcoma (STS) resection has been a great challenge. The objective of this study was to evaluate the effectiveness of a novel, simple, and cheap skin-stretching device (bidirectional regulation-hook skin closure system, BHS) for closing large skin-soft tissue defects resulting from the removal of STS and the complications associated with the use of the BHS. Methods From January 2017 to September 2018, 25 patients with STS underwent BHS therapy after tumor resection. BHS was used for two main clinical applications: securing wound closure after high-tension suture closure and delayed wound closure. We described a detailed reconstruction procedure regarding this therapy. Wound closure and complications associated with BHS therapy were recorded. We also analyzed tumor recurrence and metastases. Results All patients were observed for 16–36 months with an average follow-up of 25.6 months. During the follow-up period, no significant functional restriction was observed and the final scar was aesthetically acceptable. Superficial wound infection occurred in six patients, wound edge ischemia in two patients, and small skin tears in two patients. Two patients developed pulmonary metastasis, two patients had a local recurrence, and one patient died of pulmonary metastasis. Conclusions BHS therapy can effectively close large skin-soft tissue defects following STS resection and obtain acceptable functional results, without severe complications. However, larger studies are required to further evaluate the effectiveness, indications, and complications of BHS therapy.

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