Transient hyperthyrotropinemia in outpatient children treated due to acute infections of the respiratory system

The comparative analysis of primary morbidity of officers involved in work with occupational hazards of chemical or radiation nature in 2007-2014 has been performed. It was established that the group of officers involved in work with organophosphorus compounds has significantly higher rate of respiratory system diseases and lower rate of primary morbidity of the circulatory system diseases than the officers involved in work with ionized radiation sources. It was demonstrated that the main contribution to the primary morbidity was made by the following classes: diseases of respiratory system, diseases of musculoskeletal system and connective tissue, diseases of digestive system and diseases of circulatory system. The primary morbidity for leading categories of diseases among military personnel who worked with organophosphorus compounds in two regimes (immediate activities to destroy organophosphorus compounds and support for this process (guard, medical and fire services) did not depend on the nature of work. The rate of respiratory system diseases was relatively higher among all Russian Federation Armed forces servicemen and among those who worked with highly toxic substances (mainly due to acute infections of the upper respiratory tract). For the other classes considered the primary morbidity was higher in the risk groups. Evaluation of the role of specific nosological forms showed that in a group of servicemen working with organophosphorus compounds the rates of acute infections of the upper respiratory tract of multiple and unspecified localization, other nasal and nasal sinuses diseases, dorsalgia predominated but was inferior to the incidence of chronic ischemic heart disease. In this connection it is necessary to elaborate and conduct the preventive measures against above mentioned categories of diseases and main nosological forms of these categories.

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Transient Hyperthyrotropinemia in Outpatient Children with Acute Infections of the Respiratory System

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18084115 ◽

2021 ◽

Vol 18 (8) ◽

pp. 4115

Author(s):

Katarzyna Adamczewska ◽

Zbigniew Adamczewski ◽

Magdalena Stasiak ◽

Andrzej Lewiński ◽

Renata Stawerska

Keyword(s):

Respiratory Tract ◽

Respiratory System ◽

Complete Blood Count ◽

Preliminary Finding ◽

Acute Respiratory Tract Infection ◽

Thyroid Stimulating Hormone ◽

Healthy Children ◽

Reactive Protein ◽

Acute Infections ◽

Tract Infections

Background: Diagnostics of thyroid disorders (TD) are frequently based on the measurements of thyroid stimulating hormone (TSH) concentration only. If TSH is outside the reference range, the diagnostic procedure used in patients with TD isintroduced. Observations indicate that in a considerable number of these patients, TD is not confirmed. The aim of the study was to assess the incidence of transient hyperthyrotropinemia in healthy children during acute infections of the respiratory system. Patients and Methods: The study included consecutive children (49 boys and 45 girls), aged 2.2–17.3 years, who visited one General Practitioner (GP) due to respiratory tract infections. The tests: complete blood count (CBC), C-reactive protein (CRP), TSH and FT4 were run on the next day after the visit at the physician’s (initial visit) and ≥2 weeks after recovery. Results: Among these children, elevated TSH values were found in about 10% of patients, and they went back to normal values after recovery. A prospective analysis showed a reduction of TSH values in approx. 65% of all groups and TSH at the follow-up visit was significantly lower. Conclusions: Transient hyperthyrotropinemia was observed in about 10% of children with acute respiratory tract infection. This preliminary finding remains unexplained.

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