scholarly journals Determinants of GH resistance in malnutrition

2013 ◽  
Vol 220 (3) ◽  
pp. R57-R65 ◽  
Author(s):  
Pouneh K Fazeli ◽  
Anne Klibanski
Keyword(s):  
Anorexia Nervosa ◽  
Adaptive Response ◽  
Sirtuin 1 ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Nutrient Deficiencies ◽  
Protein Calorie Malnutrition ◽  
Chronic Undernutrition ◽  
Low Levels ◽  
Gh Resistance

States of undernutrition are characterized by GH resistance. Decreased total energy intake, as well as isolated protein–calorie malnutrition and isolated nutrient deficiencies, result in elevated GH levels and low levels of IGF1. We review various states of malnutrition and a disease state characterized by chronic undernutrition – anorexia nervosa – and discuss possible mechanisms contributing to the state of GH resistance, including fibroblast growth factor 21 and Sirtuin 1. We conclude by examining the hypothesis that GH resistance is an adaptive response to states of undernutrition, in order to maintain euglycemia and preserve energy.

Relationship of fibroblast growth factor 21, sirtuin 1, visfatin, and regulators in children with short stature

2018 ◽  
Vol 36 (3-4) ◽  
pp. 172-177
Author(s):  
Davut Sinan Kaplan ◽  
Asuman Canak ◽  
Emregul Isık ◽  
Mustafa Orkmez ◽  
Burcu Kumru
Keyword(s):  
Growth Factor ◽  
Short Stature ◽  
Fibroblast Growth Factor ◽  
Sirtuin 1 ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Relationship Of

Fibroblast growth factor-21 predicts adverse outcome in community-acquired pneumonia

2018 ◽  
Author(s):  
Fahim Ebrahimi ◽  
Carole Wolffenbuttel ◽  
Claudine A Blum ◽  
Beat Muller ◽  
Philipp Schuetz ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Adverse Outcome ◽  
Community Acquired Pneumonia ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth

Effects of anti-inflammatory treatment on fibroblast growth factor-21 in obesity and metabolic syndrome

2019 ◽  
Author(s):  
Fahim Ebrahimi ◽  
Sandrine Urwyler ◽  
Matthias Betz ◽  
Emanuel Christ ◽  
Philipp Schuetz ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Anti Inflammatory

Fibroblast growth factor 21 (FGF21) in hyper- and hypothyroidism, association with metabolic disturbances

2020 ◽  
Author(s):  
Ewa Szczepańska ◽  
Małgorzata Gietka-Czernel ◽  
Piotr Glinicki ◽  
Helena Jastrzębska ◽  
Jadwiga Słowińska-Srzednicka ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Metabolic Disturbances
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