Abstract
Background: Prolonged mechanical ventilation (PMV) among acute type A aortic dissection (AAAD) may affect the prognosis, but poorly known about the direct economic burden of PMV in patients with AAAD. The present study was contributing to filling this knowledge gap.Methods: This present study was a retrospective cohort study. Age, gender, payment methods, and postoperative complications were matched at a 1:1 ratio by using a propensity score analysis of AAAD patients. The direct economic burden was expressed as the median 1:1 differences of various hospital costs and length of stay (LOS). The Wilcoxon signed-rank tests were used to compare the difference of direct economic burden at mechanical ventilation (MV) and PMV patients.Results: A total of 464 patients, PMV occurred in 142(30.6%) patients, and 218 patients were enrolled in the matched analysis. The estimated total direct economic burden of PMV was $4970.28(P<0.05). Among different hospital costs, western medicine ($3183.23) accounted for the highest category in the economic burden, followed by blood transfusion ($250.81) and materials fees ($207.43). The median hospital and Intensive Care Unit LOS in PMV groups were prolonged 5 days than those in MV groups (P < 0.05).Conclusions: Postoperative PMV was associated with increased economic burden among AAAD patients. This study emphasizes the need for early detection and management of PMV to reduce the economic burden.
Admission Hyperglycemia in Acute Type A Aortic Dissection Predicts for a Prolonged Duration of Mechanical Ventilation
