scholarly journals Effect of W mutant Gene for Cell Growth and Differentiation.

1991 ◽  
Vol 7 ◽  
pp. 19-23
Author(s):  
Yukio NISHINA ◽  
Yoshitake NISHIMUNE ◽  
Yukihiko KITAMURA
Keyword(s):  
Cell Growth ◽  
Mutant Gene ◽  
Cell Growth And Differentiation

scholarly journals IL-4 and anti-CD40 protect against Fasmediated B cell apoptosis and induce B cell growth and differentiation

1996 ◽  
Vol 8 (5) ◽  
pp. 791-798 ◽  
Author(s):  
Kenji Nakanishi ◽  
Kiyoshi Matsui ◽  
Shin-ichiro Kashiwamura ◽  
Yasuhiro Nishioka ◽  
Jun Nomura ◽  
...  
Keyword(s):  
Cell Growth ◽  
B Cell ◽  
Cell Apoptosis ◽  
Cell Growth And Differentiation

Immunologic Control of Vascular Cell Growth and Differentiation

1989 ◽  
Vol 14 ◽  
pp. S82-S84
Author(s):  
Göran K. Hansson ◽  
Jan Holm ◽  
Lena Jonasson ◽  
Paul S. Seifert ◽  
Sten Stemme
Keyword(s):  
Cell Growth ◽  
Vascular Cell ◽  
Cell Growth And Differentiation ◽  
Immunologic Control

scholarly journals p300 Alters Keratinocyte Cell Growth and Differentiation through Regulation of p21Waf1/CIP1

PLoS ONE ◽  
2010 ◽  
Vol 5 (1) ◽  
pp. e8369 ◽  
Author(s):  
Ping-Pui Wong ◽  
Adam Pickard ◽  
Dennis J. McCance
Keyword(s):  
Cell Growth ◽  
Keratinocyte Cell ◽  
Cell Growth And Differentiation

Clonal Selection in B-Cell Growth and Differentiation

1987 ◽  
Vol 99 (1) ◽  
pp. 53-69 ◽  
Author(s):  
Tomas Leanderson ◽  
Jan Andersson ◽  
Ramanujam Rajasekar
Keyword(s):  
Cell Growth ◽  
B Cell ◽  
Clonal Selection ◽  
Cell Growth And Differentiation

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation

1988 ◽  
Vol 8 (2) ◽  
pp. 963-973
Author(s):  
J T Holt ◽  
R L Redner ◽  
A W Nienhuis
Keyword(s):  
Cell Growth ◽  
Protein Concentration ◽  
Myeloid Differentiation ◽  
Sequence Specificity ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation ◽  
Steady State Levels ◽  
Cell Growth And Differentiation ◽  
Antisense Oligomer

To study the role of a nuclear proto-oncogene in the regulation of cell growth and differentiation, we inhibited HL-60 c-myc expression with a complementary antisense oligomer. This oligomer was stable in culture and entered cells, forming an intracellular duplex. Incubation of cells with the anti-myc oligomer decreased the steady-state levels of c-myc protein by 50 to 80%, whereas a control oligomer did not significantly affect the c-myc protein concentration. Direct inhibition of c-myc expression with the anti-myc oligomer was associated with a decreased cell growth rate and an induction of myeloid differentiation. Related antisense oligomers with 2- to 12-base-pair mismatches with c-myc mRNA did not influence HL-60 cells. Thus, the effects of the antisense oligomer exhibited sequence specificity, and furthermore, these effects could be reversed by hybridization competition with another complementary oligomer. Antisense inhibition of a nuclear proto-oncogene apparently bypasses cell surface events in affecting cell proliferation and differentiation.

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