scholarly journals How Do Surgical Stress and Low Perioperative Serum Protein and Albumin Impact Upon Short Term Morbidity and Mortality in Gastric Cancer Surgery?

2017 ◽  
Vol 90 (1) ◽  
pp. 71-85 ◽  
Author(s):  
Alexandru Munteanu ◽  
Doru Munteanu ◽  
Stefan Tigan ◽  
Adrian Bartos ◽  
Cornel Iancu
Keyword(s):  
Gastric Cancer ◽  
Postoperative Complications ◽  
Total Gastrectomy ◽  
Serum Proteins ◽  
Surgical Stress ◽  
Subtotal Gastrectomy ◽  
Total Serum ◽  
Total Proteins ◽  
Short Term ◽  
Gastric Cancer Surgery

Background. Patients undergoing surgery for gastric cancer may be expected to develop a certain range of postoperative complications. This retrospective cohort study determined if gauging the serum value of total proteins and albumins before and especially after surgery can predict an undesired short term outcome in patients with gastric resections for cancer, as we have not found studies debating the link between low postoperative total proteins or albumins and early postoperative morbidity.Methods. A total of 195 patients with gastric cancer who had been subjected to gastric resection (83 patients) or total gastrectomy (111 patients), were subsequently arranged into study group pairs. In each of these group pairs, one group had a complication, while another was without said complication, or total vs. subtotal gastrectomy, etc. Each of these group pairs were compared between them in order to determine if total serum proteins and/or albumins, before and/or after surgery could predict the onset of certain complications or death. In the end, we performed ROC curves to determine the predictability value of variables for certain complications.Results. preoperative serum albumin can predict an early onset of anastomotic leakage (p=0.02) as it can predict the occurrence of general complications (p=0.018) and surgical wound infections (p=0.029) as well as a higher risk of reoperation for the management of complications (p=0.028). Total serum protein may be tied to a higher surgical stress, like albumin, as it was significantly lower in patients undergoing total gastrectomy as compared to those subjected to subtotal gastrectomy (p=0.0001 total proteins, p=0.0001 albumins). Postoperative low total serum proteins and albumins translate in a risk of early postoperative death (p=0.031 total proteins, p=0.001 albumins).Conclusion. We demonstrated the fact that total serum proteins and serum albumins, checked both before and after surgery, are of great value in helping predict a series of postoperative complications in gastric cancer surgery and that they can also be used as surgical stress markers.

Postoperative Complications and Functional Results After Subtotal Gastrectomy with Billroth II Reconstruction for Primary Gastric Cancer

2007 ◽  
Vol 52 (8) ◽  
pp. 1757-1763 ◽  
Author(s):  
Corrado Pedrazzani ◽  
Daniele Marrelli ◽  
Bernardino Rampone ◽  
Alfonso De Stefano ◽  
Giovanni Corso ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Postoperative Complications ◽  
Subtotal Gastrectomy ◽  
Functional Results ◽  
Billroth Ii ◽  
Primary Gastric Cancer ◽  
Billroth Ii Reconstruction

Short-Term Results of Laparoscopic Esophagojejunostomy using Linear Staplers after Total Gastrectomy for Gastric Cancer

2017 ◽  
Vol 152 (5) ◽  
pp. S1245
Author(s):  
Toshinaga Nabae ◽  
Toshitatu Ogino ◽  
Hideyo Kimura ◽  
Shiho Nishimura ◽  
Takanori Mei ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Total Gastrectomy ◽  
Short Term

scholarly journals The Feasibility of Short Term Prophylactic Antibiotics in Gastric Cancer Surgery

2010 ◽  
Vol 10 (4) ◽  
pp. 206 ◽  
Author(s):  
Jun Suh Lee ◽  
Han Hong Lee ◽  
Kyo Young Song ◽  
Cho Hyun Park ◽  
Hae Myung Jeon
Keyword(s):  
Gastric Cancer ◽  
Prophylactic Antibiotics ◽  
Cancer Surgery ◽  
Short Term ◽  
Gastric Cancer Surgery

scholarly journals Robotic oesophago-gastric cancer surgery

2018 ◽  
Vol 100 (6_sup) ◽  
pp. 27-35 ◽  
Author(s):  
YA Qureshi ◽  
B Mohammadi
Keyword(s):  
Gastric Cancer ◽  
Robotic Surgery ◽  
Postoperative Complications ◽  
Minimally Invasive ◽  
Cancer Surgery ◽  
Minimally Invasive Techniques ◽  
Gastric Cancer Surgery ◽  
Complications Rate ◽  
Invasive Techniques

A postoperative complications rate of nearly 50% has compelled oesophago-gastric practice to adopt minimally invasive techniques such as robotic surgery

Late term renal complications related to chemoradiotherapy in patients with gastric cancer

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 15033-15033
Author(s):  
A. Mayadagli ◽  
O. O. Seseogullari ◽  
C. Gemici ◽  
A. Ozkan ◽  
C. Parlak ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Total Gastrectomy ◽  
Renal Damage ◽  
Statistical Significance ◽  
Combined Treatment ◽  
Subtotal Gastrectomy ◽  
Renal Scintigraphy ◽  
Normal Range ◽  
Curative Surgery ◽  
Renal Complications

15033 Background: The aim of this study is to evaluate late term renal complications of the combined treatment with chemoradiotherapy, according to the scheme of McDonald et al, in patients diagnosed with gastric cancer, after radical curative surgery. Methods: Totally 44 patients who administered to our clinic between years 2003 and 2004, with the diagnosis of gastric cancer, and with the age-adjusted creatinine clearance test (CCT) results within normal range, were enrolled into the study. Surgical procedure was subtotal gastrectomy in 34 patients (63,6%), and total gastrectomy in 16 patients (36,4%). Total 4600 cGy radiotherapy was administered to all patients through parallel-opposed AP-PA fields in 23 fractions concomitant with chemotherapy according to the scheme of McDonald et al. One year after the completion of the treatment, a technetium 99-m renal scintigraphy (DMSA) and CCT were performed to all patients whose renal functions were within normal limits. Results: Median age in the study was 52 (22–78). 34 patients (77,3%) were male and 10 (22,7%) were female. TNM stages were stage II in 15 (34,1%), IIIA in 21 (47,7%), IIIB in 4 (9,1%), and IV in 4 cases (9,1%). CCT measured 1 year after the treatment was low in 13 patients (29,6%), and within normal range in 31 patients (70,4%). Renal scintigraphy revealed damage at one pole in 32 patients (72,7%), damage at bilateral renal poles in 8 patients (18,3%), and it was normal in 4 patients (9%). Renal damage was higher in left kidneys than right kidneys (89,9% vs. 15,4%). There was a correlation between CCT values and scintigraphical findings. Damage in bilateral renal poles was higher in cases with low CCT than in cases with normal values (85,7% vs. 15,4). In general, there were no statistically significant relationship between late term renal complications and sex, and grade III treatment-related gastrointestinal toxicity. However, the relationships with age, extent of surgery reached statistical significance (p=0.009, and =0.006). Renal damage was notably higher in older patients, and in patients who underwent total gastrectomy. Conclusions: Since postoperative chemoradiotherapy is a novel modality for the treatment of gastric cancer, more studies are required in order to evaluate chronic toxicities. No significant financial relationships to disclose.

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