scholarly journals Kidney tumor radiofrequency ablation progress in Lithuania

2013 ◽  
Vol 12 (3) ◽  
pp. 161-170
Author(s):  
Albertas Ulys ◽  
Algirdas Žalimas ◽  
Rūta Merkytė ◽  
Mantas Trakymas
Keyword(s):  
Radiofrequency Ablation ◽  
Tumor Size ◽  
Renal Tumor ◽  
Radical Surgery ◽  
Malignant Tumors ◽  
Renal Tumors ◽  
The Us ◽  
Vilnius University ◽  
Average Tumor Size

Background / ObjectiveThis retrospective study aimed to clarify one of the minimally invasive therapies – Radiofrequency ablation (RFA) – performance, extremeness and 5-year survival in patients with small renal tumors.Patients and methods118 patients (77 men (65%), and 41 women (35%) with mean age of 68.72 (± 10.12 ) years) were treated with RFA method in Vilnius University Institute of Oncology Urology Section, and since 2003 September 17 till 2012 December 6 were performed144 renal tumor RFAs. All renal tumors RFAs were performed percutaneously in the projection of the skin, under local or general anesthesia. Procedures were performed by one or several small (up to 1 cm) incisions, and in the US control electrodeswere introduced. Since May 2011, 30 RFAs were performed with three electrodes and US control with CT navigation, just a day before the operation additionally titanium markers were put in around the kidney tumor.ResultsSince 2003 till 2007 years our patient’s follow-up method was US examination. However, in case of suspicion of tumor progression, percutaneous renal biopsy and CT were performed. From 2007 year patients were follow-up with CT. The ablationzone, contrast agent accumulation and the ablation of the edge were evaluated. Average tumor size was 2.8 (± 0.9) cm. By histology, mainly there were malignant tumors, much less benign, a minority remained histologically unconfirmed.In our study we found out that the most radical renal tumor RFAs were done in the control of US with CT navigation, when additionally around the renal tumor titanium markers were added. Also we clarified, that procedure is more radical whenperformed using three electrodes. The most common postoperative complication was paranephric hematoma.ConclusionsAfter RFA, 2-year survival rate is 90 %, 5 years – 58%. Death risk factors: tumor size, higher ASA class, non-radical surgery, metastases or other oncologic process.Key words: Radiofrequency ablation, survival, observation, fiducial markers.Inkstų navikų radiodažninės abliacijos pažanga Lietuvoje Įvadas / tikslasMūsų atlikto retrospektyviojo tyrimo tikslas – išsiaiškinti vieno iš minimaliai invazinių gydymo metodų – radiodažninės abliacijos (RDA) efektyvumą, radikalumą ir mažus inkstų navikus turinčių pacientų penkerių metų išgyvenamumą.Ligoniai ir metodai118 pacientų (77 vyrai (65 %) ir 41 moteris (35 %), amžiaus vidurkis 68,72 ± 10,12 metų) buvo gydyti RDA metodu Vilniaus universiteto Onkologijos instituto (VUOI) Urologijos skyriuje. Jiems nuo 2003 m. rugsėjo 17 d. iki 2012 m. gruodžio 6 d. buvo atliktos 144 inkstų navikų RDA. VUOI visos inkstų navikų RDA atliktos perkutaniškai, kai sukėlus vietinę ar bendrąją nejautrą, inksto projekcijos odoje atliekama viena ar kelios nedidelės (iki 1 cm) incizijos, per kurią/kurias kontroliuojant ultragarsu (UG) įkišami elektrodai ir atliekama RDA procedūra. Nuo 2011 m. gegužės 30 d. atliktos RDA su trimis elektrodais, kontroliuojamos ultragarsu su kompiuterinės tomografijos (KT) navigacija, tik dieną prieš operaciją papildomai UG kontroliuojamu būdu suleidus titaninių žymenų (TŽ) aplink inksto naviką.RezultataiMūsų tyrime nuo 2003 m. iki 2007 m. taikytas ultragarsinis ligonių stebėjimo metodas. Įtarus lokalų naviko progresavimą, buvo atliekama perkutaninė inksto biopsija ir KT. Nuo 2007 m. stebėta tik atliekant KT, kurios metu vertinta abliacijos zona, kontrastinės medžiagos (k/m) kaupimas joje ir abliacijos kraštas. Vidutinis naviko dydis buvo 2,8 (± 0,9) cm. Pagal histologiją, daugiausia buvo piktybinių navikų, daug mažiau – gerybinių, mažoji dalis liko histologiškai nepatvirtinta.Radikaliausios inkstų navikų RDA buvo atliktos kontroliuojant UG su KT navigacija ir prieš operaciją UG kontroliuojamu būdu papildomai suleidus aplink naviką titaninių žymenų. RDA yra radikalesnė, kai atliekama naudojant tris elektrodus. Duomenys parodė, kad dažniausia pooperacinė komplikacija buvo paranefrinė hematoma.IšvadosPo RDA procedūros apskaičiuota dvejų metų išgyvenamumo tikimybė – 90 %, penkerių metų – 58 %. Mūsų tyrime nustatyti mirties rizikos veiksniai – naviko dydis, aukštesnė ASA klasė, neradikali operacija, metastazės iš anamnezės, kito organo onkologinis procesas.Reikšminiai žodžiai: radiodažninė abliacija, išgyvenamumas, stebėjimas, titaniniai žymenys.

Percutaneous radiofrequency ablation therapy as a first choice for renal tumor in patients with von Hippel-Lindau disease.

2011 ◽  
Vol 29 (7_suppl) ◽  
pp. 375-375
Author(s):  
K. Uematsu ◽  
T. Saika ◽  
D. Kanbara ◽  
Y. Kobayashi ◽  
H. Gobara ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Survival Rate ◽  
Renal Tumor ◽  
Renal Tumors ◽  
Therapeutic Effects ◽  
Ablation Therapy ◽  
Von Hippel Lindau ◽  
First Choice ◽  
Radiofrequency Ablation Therapy

375 Background: Forty percent of patients with von Hippel-Lindau (VHL) disease have multifocal, bilateral renal cell carcinoma (RCC). The advent of ablative therapy has allowed many of these tumors to be approached percutaneously. Probe-based radiofrequency ablation (RFA) have recently been shown to be feasible nephron-sparing therapies for RCC, and have been proposed as first-line treatments for patients with VHL. We evaluated the feasibility, safety and therapeutic effects of RFA for VHL patients. Methods: We reviewed the outcomes of VHL patients with RCC treated by RFA from 2003 to 2010. Follow-up consisted of serum creatinine measurement, physical examination and serial contrast enhanced computerized tomography or magnetic resonance imaging. Results: The 42 tumors of 15 patients (23-70 years old, median 40) received a total of 43 RFA treatments to a 7 to 28 mm renal tumor (median 16). Seven of the patients had bilateral renal tumors. Tumor enhancement was eliminated and the renal function was preserved after the treatment in all tumors. There were no major complications related to the procedures though eight of small subcapsular hematomas, one of hematuria, one of small urine overflow, and one of nausea were seen after RFA. There was no recurrence after RFA during a mean follow-up period of 28.9 months (range 4.0-89.0, median 20.0 months). The overall recurrence-free survival rate was 100%. There was also a 100% metastasis-free and disease specific survival rate in the cohort. Conclusions: The result of the present study showed percutaneous RFA was a feasible, safe, and promising therapy for the treatment of VHL patients with RCC. No significant financial relationships to disclose.

scholarly journals Analysis of Radiofrequency Ablation of Small Renal Tumors in Patients at High Anesthetic and Surgical Risk: Urologist Experience with Follow-up Results in the Initial Six Months

2013 ◽  
Vol 14 (11) ◽  
pp. 6637-6641
Author(s):  
Mehmet Bilgehan Yuksel ◽  
Ayhan Karakose ◽  
Bilal Gumus ◽  
Serdar Tarhan ◽  
Yusuf Ziya Atesci ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Renal Tumors ◽  
Surgical Risk

scholarly journals Radiofrequency Ablation of Renal Tumors: Four-Year Follow-Up Results in 47 Patients

2012 ◽  
Vol 13 (5) ◽  
pp. 625 ◽  
Author(s):  
Soo Dong Kim ◽  
Seong Guk Yoon ◽  
Gyung Tak Sung
Keyword(s):  
Radiofrequency Ablation ◽  
Renal Tumors

1105: Peripheral Temperature Monitoring to Augment Percutaneous Radiofrequency Ablation: Intermediate Follow Up of 65 Renal Tumors

2007 ◽  
Vol 177 (4S) ◽  
pp. 365-365
Author(s):  
Marshall S. Wingo ◽  
Robert I. Carey ◽  
Eliecer Kurzer ◽  
Farjaad M. Siddiq ◽  
Alvin Lopez-Pujals ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Temperature Monitoring ◽  
Renal Tumors ◽  
Percutaneous Radiofrequency Ablation ◽  
Peripheral Temperature

Percutaneous radiofrequency ablation of renal tumours: 29-month mean follow-up results of 118 patients

2014 ◽  
Vol 20 (4) ◽  
pp. 219-228
Author(s):  
Albertas Ulys ◽  
Algirdas Žalimas ◽  
Rūta Merkytė ◽  
Sandra Selickaja ◽  
Mantas Trakymas
Keyword(s):  
Radiofrequency Ablation ◽  
Thermal Effects ◽  
Renal Tumors ◽  
Percutaneous Radiofrequency Ablation ◽  
Ultrasound Guided ◽  
Kidney Tumors ◽  
Renal Tumours ◽  
Invasive Method ◽  
The Mean

Background. Percutaneous radiofrequency ablation (RFA) is a minimally invasive method of treatment based on thermal effects. This retrospective study aimed to clarify percutaneous RFA of kidney tumors  –  performance, extremeness and 5-year survival in patients with small renal tumors in a single center. Materials and methods. Between September 2003 and December 2012, a total of 118 patients underwent percutaneous RFA of renal tumors. During more than 9  years period 144 RFA procedures were performed. Tumors were verified by biopsy. We used 3 RFA techniques: RFA under ultrasound control only (US), ultrasound guided RFA with CT navigation (US/CT) and ultrasound guided RFA with CT navigation, fiducial markers placed around the kidney tumor before the treatment (US/CT/FM). RFA electrodes were one and three. Patients were followed up regularly by CT with contrast enhancement. Results. The mean patient age was 68.72  years (range 28 to 86). The mean tumor size was 2.8 cm (range 1 to 5.4). The mean follow-up time was 29 months (1–111 months). Radical dependence on technical procedures: only US  39 (66.1%), US/CT 18 (94.7%), US/CT/FM 37 (92.5%), p = 0.001. Radical differences between using one and three electrodes: 39 (66.1%) and 55 (93.2%), p 

The Role of Radiotherapy in the Treatment of Malignant Tumors of the Salivary Glands

1980 ◽  
Vol 66 (4) ◽  
pp. 467-474 ◽  
Author(s):  
Marian Reinfuss ◽  
Stanislaw Korzeniowski
Keyword(s):  
Salivary Gland ◽  
Radical Surgery ◽  
Malignant Tumors ◽  
Postoperative Radiotherapy ◽  
Clinical Stage ◽  
Distant Metastases ◽  
Treatment Results ◽  
High Incidence

Treatment results in a group of 70 patients with salivary gland tumors were analyzed. Prognosis appeared to correlate with both clinical stage and malignancy of tumors. In patients irradiated postoperatively because of nonradical operation, a higher 5-year survival rate was achieved than in patients after radical surgery. It is suggested that postoperative radiotherapy improves treatment results in patients with T2 and T3 lesions. In unresectable cases (T4) a 13 % 5-year survival was achieved. In patients with highly malignant cancers a high incidence (41.9 %) of distant metastases was observed during the 5-year follow-up.

Laparoscopic Radiofrequency Ablation of Renal Tumors: 32-Month Mean Follow-up Results of 106 Patients

Urology ◽  
2011 ◽  
Vol 77 (4) ◽  
pp. 798-802 ◽  
Author(s):  
Changwei Ji ◽  
Xiaogong Li ◽  
Shiwei Zhang ◽  
Weidong Gan ◽  
Gutian Zhang ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Renal Tumors ◽  
Laparoscopic Radiofrequency Ablation

scholarly journals Laparoscopic Adrenalectomy for Potentially Malignant Adrenal Tumors Greater than 5 Centimeters

2006 ◽  
Vol 91 (8) ◽  
pp. 3080-3083 ◽  
Author(s):  
Chun-Hou Liao ◽  
Shih-Chieh Chueh ◽  
Ming-Kuen Lai ◽  
Po-Jen Hsiao ◽  
Jun Chen
Keyword(s):  
Tumor Size ◽  
Laparoscopic Adrenalectomy ◽  
Malignant Tumors ◽  
Adrenal Tumors ◽  
Benign Tumors ◽  
Conversion To Open Surgery ◽  
Open Conversion ◽  
Potentially Malignant ◽  
Adrenocortical Carcinomas

Abstract Purpose: Laparoscopic adrenalectomy (LA) is controversial for large, potentially malignant tumors. We report a series of LA or hand-assisted LA for large (>5 cm) adrenal tumors. Patients and Methods: Among 210 LAs performed in 6 yr, 39 patients had potentially malignant tumors greater than 5 cm in diameter. Their perioperative and follow-up data were retrospectively analyzed. Results: All 39 patients had successful LAs without perioperative mortality, conversion to open surgery, or capsular disruption during dissection. The mean tumor size was 6.2 cm (range, 5–12 cm), operative time 207 min (115–315 min), and blood loss 75 ml (minimal–1400 ml). Complications included one intraoperative diaphragmatic perforation, three mild wound infections, and one pneumonia. Preoperatively there were 27 nonfunctioning tumors, seven pheochromocytomas, three cortisol-secreting tumors, and two virilizing tumors. Final pathology revealed eight malignant (four adrenocortical carcinomas and four metastatic carcinomas) and 31 benign tumors (14 cortical adenomas, eight pheochromocytomas, six myelolipomas, and three ganglioneuromas). Median follow-up was 39 months. Four patients (two adrenocortical carcinomas, one metastatic hepatoma, and one lymphoma) died 24, 10, 9, and 3 months after surgery, respectively. A hand-assisted device was used in 10 patients. Only the tumor size was larger and length of postoperative hospital stay longer for those in the hand-assisted group. Conclusions: LA is a reasonable option for selected large adrenal tumors when complete resection is technically feasible and there is no evidence of local invasion. Hand-assisted LA is a good alternative to open conversion if a difficult dissection is encountered intraoperatively.

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