scholarly journals SEMIQUANTITATIVE EVALUATION OF 99MTCTRODAT1 BINDING POTENTIAL BY TWO METHODS OF SPECT IMAGE RECONSTRUCTION.

2019 ◽  
Vol 7 (2A) ◽  
Author(s):  
Melissa Furlaneto Lellis Leite ◽  
Marilia Alves dos Reis ◽  
Cássio Miri Oliveira ◽  
Mario Luiz Vieira Castiglioni ◽  
Rodrigo Affonseca Bressan
Keyword(s):  
Image Reconstruction ◽  
Effect Size ◽  
Neurological Disorders ◽  
Visual Inspection ◽  
Binding Potential ◽  
Back Projection ◽  
Large Effect Size ◽  
Spect Image ◽  
Reconstruction Methods ◽  
Semiquantitative Evaluation

TRODAT-1 is a radiopharmaceutical derived from tropane and linked to tecnecium-99m ([99mTc] TRODAT-1) has been used in studies of dopamine transporter (DAT) in central nervous system. Associated with the SPECT technique of acquisition, is able to detect changes in neurological disorders like Parkinson´s disease, evaluating the binding potential (BP) of DAT. The aim of this study was to evaluate the influence of the image reconstruction methods, Filtered Back Projection (FBP) and iterative reconstruction (OSEM), in BP values at the striatal region in 30 healthy volunteers. Images were analyzed by visual inspection and semi-quantitative analysis. Regions of interest (ROI) were made over striatal areas on both sides. Nonparametric Wilcoxon statistical analysis was performed between the BP values from the FBP and OSEM methods. Our results showed that the reconstruction methods have a statistical significant BP values difference in the total striatum (Z = -2,2787 p = 0.005), right striatum (Z = -2,602 p = 0.009) and left striatum (Z= 2,746 p = 0.006). The effect size was calculated to see if there influence in this test: the "large effect size" for all measurements was observed (total striatum r= -0.51; right striatum r= -0.48; left striatum r= -0.50). FBP is the usual method of reconstruction for brain SPECT images, and our results showed influence of the OSEM method in BP. It is concluded that the method of image reconstruction adopted should be standardized to avoid incorrect evaluations of BP values using [99mTc]TRODAT-1.

Image Reconstruction Methods for Ultrasonic Transmission Mode Tomography in Bubbly Flow Regime

2014 ◽  
Vol 70 (3) ◽  
Author(s):  
Mahdi Faramarzi ◽  
Sallehuddin Ibrahim ◽  
Mohd Amri Md Yunus ◽  
Jaysuman Pusppanathan
Keyword(s):  
Image Reconstruction ◽  
Flow Regime ◽  
Signal To Noise Ratio ◽  
Bubbly Flow ◽  
Flow Regimes ◽  
Transmission Mode ◽  
Back Projection ◽  
Reconstruction Methods ◽  
On Line ◽  
Line Process

Image reconstruction from projections plays an important role in monitoring flow regimes by ultrasonic transmission mode tomography (UTMT) system. Fast and more accurate methods are necessary in case of on-line process e.g. bubbly flow regimes. In this work, analytical image reconstruction methods such as linear back projection (LBP), filter back projection (FBP) and convolution back projection (CBP) in bubbly flow regime is investigated and found that CBP is superior to other methods. Furthermore, different filters were applied to CBP to investigate the image quality improvement. Among different types of filters for CBP method, Ram-lack outperforms the others for UTMT. The peak signal to noise ratio (PSNR) of reconstructed images in this particular experiment was improved using Ram-lack in noiseless data.  

Region of interest evaluation of SPECT image reconstruction methods using a realistic brain phantom

1997 ◽  
Vol 44 (3) ◽  
pp. 1336-1341 ◽  
Author(s):  
W. Xia ◽  
S.J. Glick ◽  
Tin-Su Pan ◽  
E.J. Soares ◽  
Der-Shan Luo
Keyword(s):  
Image Reconstruction ◽  
Region Of Interest ◽  
Spect Image ◽  
Reconstruction Methods ◽  
Brain Phantom

Caffeine supplementation for 4-day, followed by acute ingestion, did not impact triathlete output power after submaximal intensity exercise

2019 ◽  
Vol 18 (3) ◽  
pp. 118
Author(s):  
Anderson Pontes Morales ◽  
Felipe Sampaio-Jorge ◽  
Thiago Barth ◽  
Alessandra Alegre De Matos ◽  
Luiz Felipe Da Cruz Rangel ◽  
...  
Keyword(s):  
Blood Lactate ◽  
Output Power ◽  
Body Mass ◽  
Effect Size ◽  
Power Output ◽  
Anaerobic Power ◽  
Lactate Concentration ◽  
Wingate Test ◽  
Large Effect Size ◽  
Acute Ingestion

Introduction: The aim of this study was to test the hypothesis that caffeine supplementation (6 mg·kg-1 body mass) for 4-days, followed by acute intake, would impact five male triathletes output power after performed submaximal intensity exercise. Methods: This was a randomized, double-blind, placebo-controlled crossover study, placebo (4-day) - placebo (acute) PP, placebo (4-days) -caffeine (acute) PC, and caffeine (4-day) - caffeine (acute) CC. Participants abstained from dietary caffeine sources for 4 days and ingested capsules containing either placebo or caffeine (6 mg.kg-1 body mass day in one absorption). The acute trials the capsules containing placebo or caffeine (6 mg.kg-1 body mass day in one absorption) were ingested 60min before completing exercise in a treadmill for 40min (80% VO2max) and to perform the Wingate test. Results: Blood lactate was determined before, 60min after ingestion, and immediately after the exercise on the treadmill, the Wingate test, and after the recovery (10-min). CC and PC trials did not change the cardiopulmonary variables (P>0.05) and the anaerobic power variables (peak/mean power output and fatigue index) (P>0.05). The PC trial compared with PP promoted improvements in the curve power output in 2 sec by 31.19% (large effect-size d = 1.08; P<0.05) and 3 sec by 20% (large effect-size d = 1.19; P<0.05). A 10min recovery was not sufficient to reduce blood lactate concentration in the PC trial compared with PP (PC, 13.73±2.66 vs. PP, 10.26±1.60 mmol.L-1; P<0.05, respectively) (P<0.05). Conclusion: In conclusion, these results indicate that caffeine supplementation (6 mg·kg-1 body mass) for 4 days, followed by acute ingestion, did not impact the triathletes output power after performed submaximal intensity exercise. Nutritional interventions may help researchers and athletes to adapt strategies for manipulating caffeine use.Key-words: caffeine metabolism, Wingate test, blood lactate, performance.

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