scholarly journals Antibiotic sensitivity patterns of uropathogens isolated from catheterized patients in a tertiary care hospital in Dhaka, Bangladesh

2021 ◽  
Vol 9 (3) ◽  
pp. 61-66
Author(s):  
Sunzida Arina ◽  
SM Shamsuzzaman

Among nosocomial infections catheter associated urinary tract infection (CAUTI) is one of the most common infection. The antibiotic resistance amongst the uropathogens isolated from CAUTI are multi-drug resistant and a growing public health problem in the world including Bangladesh. The study objective was to determine the aetiology of uropathogens in catheter associated urinary tract infection and find out their anti-microbial sensitivity pattern among the isolates. A cross sectional study was done from July 2016 to June 2017 in Dhaka Medical College, Bangladesh. Urine samples were collected from 400 patients with suspected CAUTI which were processed microbiologically and antimicrobial sensitivity was performed. Out of 400 patients Escherichia coli (38.93%) was the most common isolated organism followed by Pseudomonas spp, (15.98%), Klebsiella spp, (8.61%), Proteus spp. (7.38%) Enterobacter spp, (6.56%) and Acinitobacter spp. (1.22%). Among the Gram positive isolates Staphylococcus aureus (1.64%) and Coagulase negative Staphylococeus (6.97%%) were isolated. Enterobacteriaceae showed high resistant to commonly used antimicrobials Amoxiclav, Gentamycin, Ceftriaxone, azithromycin , ciprofloxacin, cortimoxazole and were sensitive to colistin ,nitrofurantoin ,imepenem, Meropenem. Many isolates showed multi- drug resistance pattern hence strict aseptic precaution has to be taken prior to catheter insertion and after to prevent infection.

2020 ◽  
Vol 21 (2) ◽  
pp. 93-97
Author(s):  
AKM Humayon Kabir ◽  
SK Jakaria Been Sayeed ◽  
Prodip Kumar Biswas ◽  
SM Hafiz ◽  
Md Uzzwal Mallik ◽  
...  

Urinary tract infection is one of the most common bacterial infections seen in clinical practice both in developed and developing countries. The causative agents of Urinary tract infection vary from place to place and they also vary in their susceptibility and resistance patterns. This descriptive study aimed to evaluate the antibiotic susceptibility patterns of pathogens isolated from routine laboratory specimens at Dhaka Medical College Hospital. A descriptive cross- sectional study was done from January 2018 to June 2018. A total of 100 mid-stream urine samples from the suspected UTI patients were tested microbiologically and antimicrobial susceptibility test were performed for the isolated pathogens using Kirby-Bauer disk diffusion method with positivity rate of UTI was 90% (90/100). Escherichia coli (39%) was the most UTI causing bacteria followed by Klebsiella 18(18%), Acinetobacter 12(12%), Staphylococci, 9 (9%), Pseudomonas 6 (6%), Enterococcus species 3 (3%) and Proteus 3 (3%). Female 83 (83%) were more affected in comparison with male. Adult female especially age range 18-30 years were found in high risk. Nitrofurantoin, Amikacin and Meropenem were recorded as most sensitive antibiogram for most of the bacteria’s whereas cephalosporin showed increased resistance. However, for uncomplicated community acquired UTI, Nitrofurantoin (oral) and Amikacin (Injectable) can be chosen as first line medication. J MEDICINE JUL 2020; 21 (2) : 93-97


2014 ◽  
Vol 9 (3) ◽  
pp. 45-53
Author(s):  
PK Dey ◽  
J Banerjee ◽  
RP Singh ◽  
A Pan ◽  
A Chatterjee

Objective The aim of this study was to describe the characteristics and the clinical evolution of first documented symptomatic Urinary Tract Infection and to detect underlying abnormalities of the kidney and urinary tract if any. Methods Prospective observational study on 102 patients (6 months to 5 yrs) with first documented symptomatic Urinary Tract Infection diagnosed by positive urine culture in the department of Paediatrics, G.S.V.M Medical College, Kanpur, India between January 2008 and June 2009. Antibiotics were given according to the sensitivity pattern. All children were evaluated with renal bladder ultrasonogram and voiding cystourethrography. Results Out of 102 patients 62 (60.78%) girls and 40 (39.21%) boys, most of the patients (62.7%) within 6 months to 2 years old. The commonest presentation was fever (84.3%).The commonest organism was E.Coli (80.37%). Overall most common underlying abnormality was VUR, found in 31(30.31%) children. Other abnormalities were urolithiasis(4.9%), ureteropelvic junction obstruction (3.92%),Mild hydronephrosis (2.9%), ureteric duplex(0.98%), posterior urethral valve(0.98%), renal duplex (0.98%). Conclusion In our study 45.09% children had underlying abnormalities which may be a potential risk factor for urinary tract infection. Better recognition of risk factors, prompt diagnosis and early intervention are sufficient enough to maintain normal renal function and healthy lifestyle.   Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-3, 45-53 DOI: http://dx.doi.org/10.3126/jcmsn.v9i3.10222  


2020 ◽  
Vol 10 (1) ◽  
pp. 23-26
Author(s):  
Shima Akter Khatun ◽  
Shusmita Shaha

Background: Urinary tract infection (UTI) is the most common illness affecting both males and females in almost all age groups. Hence, continuous analysis of prescribing pattern in UTI is vital. Objective: The study was designed to determine the prescribing pattern of antibiotics in UTI patients at a tertiary care hospital. Materials and Methods: A prospective observational study was carried out on 180 patients in Dhaka National Medical College Hospital from January to March 2012 by collecting data from outpatient department of Surgery, Medicine and Gynaecology & Obstetrics. Results: Analysis of prescribed drugs revealed that use of antibiotics such as nitrofurantoin (30.55%), cefuroxime (22.22%) and ciprofloxacin (16.66%) were significantly higher compared to other drugs. The most common isolated organisms were Escherichia coli (60%), Proteus (20%), Klebsiella (13.33%), and Pseudomonas (6.66%). Conclusion: Present findings are suggestive of the need for periodic monitoring of antibiotic sensitivity pattern to provide effective treatment. J Enam Med Col 2020; 10(1): 23-26


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