The effect of adiponectin gene polymorphism on the severity of metabolic disorders and some liver parameters in patients with non-alcoholic fatty liver disease in combination with hypertension

2020 ◽  
Vol 2020 (1) ◽  
pp. 95-98
Author(s):  
K.О. Prosolenko ◽  
Aging ◽  
2019 ◽  
Vol 11 (18) ◽  
pp. 7847-7858 ◽  
Author(s):  
Fang Ji ◽  
Ye Liu ◽  
Jun-Gui Hao ◽  
Li-Ping Wang ◽  
Ming-Jia Dai ◽  
...  

2019 ◽  
Vol 20 (9) ◽  
pp. 2215 ◽  
Author(s):  
Hamza El Hadi ◽  
Angelo Di Vincenzo ◽  
Roberto Vettor ◽  
Marco Rossato

With the progressive epidemics of obesity, non-alcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease in adults and children. The increasing prevalence and incidence of NAFLD with advanced fibrosis is concerning because patients appear to experience higher non-liver-related morbidity and mortality than the general population. Recent clinical evidence suggests that NAFLD is directly associated with an increased risk of cardio-metabolic disorders. This mini review describes briefly the current understanding of the pathogenesis of NAFLD, summarizing the link between NAFLD and cardio-metabolic complications, focusing mainly upon ischemic stroke, type 2 diabetes mellitus (DM), hypertension, chronic kidney disease (CKD) and cardiac arrhythmias. In addition, it describes briefly the current understanding of the pathogenesis of NAFLD.


2018 ◽  
Vol 55 (7) ◽  
pp. 561-567 ◽  
Author(s):  
Vikrant Sood ◽  
Rajeev Khanna ◽  
Dinesh Rawat ◽  
Shvetank Sharma ◽  
Seema Alam ◽  
...  

2020 ◽  
Vol 20 (7) ◽  
pp. 578-583
Author(s):  
Hui Li ◽  
Erna Jia ◽  
Yu Hong ◽  
Yanzhen Chen ◽  
Jian Jiao

Nonalcoholic Fatty Liver Disease (NAFLD) includes a variety of changes including nonalcoholic fatty liver, cirrhosis and Hepatocellular Carcinoma (HCC), which are associated with metabolic disorders and cardiovascular diseases. The pathogenesis of NAFLD is complex and multifactorial. Many studies have shown that estrogen has a protective effect on premenopausal women with metabolic disorders and non-alcoholic fatty liver disease. Estrogen supplements may, at least in theory, prevent the development and progression of NAFLD. Phytoestrogen is extracted from plants, especially legumes, whose molecular structure and biological activity are similar to those of mammals estrogen, therefore it could replace the role of estrogen and prevent the occurrence of adverse reactions to estrogen. In this article, we review the published literature related to phytoestrogens and NAFLD as well as suggest the possible mechanisms that may underlie the association between phytoestrogens and NAFLD.


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