Control, Management and Treatment of Diabetes Using Modern Drug Delivery Systems and Special Properties of Nanoparticles

2014 ◽  
Vol 3 (9) ◽  
Author(s):  
M. Rezaei-kelishadi ◽  
M. Nuri ◽  
Z. Erfani ◽  
A. Palizban ◽  
R. Parandin
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Modern Drug ◽  
Treatment Of Diabetes ◽  
Control Management

Nanobiomaterials set to revolutionize drug-delivery systems for the treatment of diabetes

2016 ◽  
pp. 487-514
Author(s):  
Abolfazl Yazdanpanah ◽  
Zahra Rezvani ◽  
Arash Ramedani ◽  
Mazaher Gholipourmalekabadi ◽  
Narendra Pal Singh Chauhan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Treatment Of Diabetes

scholarly journals СУЧАСНІ ПІДХОДИ ДО РОЗРОБКИ НАНОСИСТЕМ ДОСТАВКИ ЛІКІВ

World Science ◽  
2020 ◽  
Vol 1 (6(58)) ◽  
pp. 32-37 ◽  
Author(s):  
Olga Bilan ◽  
Iryna Brubaker ◽  
Kateryna Marchenko-Tolsta
Keyword(s):  
Drug Delivery ◽  
Interdisciplinary Research ◽  
Drug Delivery Systems ◽  
Therapeutic Agents ◽  
Delivery Systems ◽  
The Body ◽  
Target Orientation ◽  
Fast Growing ◽  
Modern Drug ◽  
Effective Drugs

The review investigates the latest developments in the field of application of nanotechnologies in the transportation of therapeutic agents, features and the advantages of using nanoscale drug delivery systems for the treatment of diseases, as well as further prospects of using this field in medicine. Modern drug delivery systems are characterized by target orientation, rapid response to the environment and the use of biocompatible and biodegradable nanomaterials which allow for the development of the next generation of more effective drugs. Interdisciplinary research in this fast-growing field provides opportunities to design and develop multifunctional devices that can accurately target and successfully administer the release and distribution of active ingredients in the body.

Nanocellulose and Nanogels as Modern Drug Delivery Systems

2017 ◽  
pp. 209-269 ◽  
Author(s):  
Misu Moscovici ◽  
Cristina Hlevca ◽  
Angela Casarica ◽  
Ramona-Daniela Pavaloiu
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Modern Drug

scholarly journals UTILIZATION OF POLYMER AND LIPID-BASED DRUG DELIVERY SYSTEMS IN TREATMENT OF NEUROLOGICAL DISORDERS- A MINI REVIEW

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Arsalan Sarmad
Keyword(s):  
Drug Delivery ◽  
Neurological Disorders ◽  
Neurological Disorder ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Water Soluble ◽  
Medical Practitioners ◽  
Modern Drug ◽  
Lipid Compounds ◽  
Pharmacologically Active

In modern drug discovery techniques consistently increasing in the number of new pharmacologically active lipid compounds these compounds are poorly water-soluble. A great challenge of making this medication for oral administration with the desired bioavailability. Epilepsy is a severe neurological disorder that needs rapid treatment. To enhancement of its bioavailability, we need to make lipid-based drugs. On other hand, the surface tension reducing agents will give poor water-soluble formulation. Treatment of Neurological disorder is still a challenge for medical practitioners because of restricted moments and barriers. The solid lipid nanoparticles (SLN) and nanoemulsions are easily avoided the blood-brain barrier. Therefore, there is a maximum therapeutic efficacy achieved by using the lipid and polymer-based drug delivery system in the treatment of neurological disorders. Keywords: Neurological disorder, Lipid, Polymer, Lipid Based Drug delivery systems, Epilepsy, Treatment.

Recent Advances in Self-Emulsifying Drug Delivery Systems

2015 ◽  
Vol 8 (1) ◽  
pp. 2693-2697
Author(s):  
Amol S Deshmukh
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Aqueous Solubility ◽  
Oral Route ◽  
Delivery Systems ◽  
Novel Technologies ◽  
Oral Formulations ◽  
Modern Drug ◽  
New Chemical Entities ◽  
Poorly Soluble

Oral route has always been preferred route for formulators and has dominated over other routes of administrations. But major problem encountered in oral formulations (as estimated more than 50 % of oral formulations are found to be poorly aqueous soluble), is low bioavailability, giving rise to further problems like, high inter and intra subject variability, lack of dose uniformity and finally leading to therapeutic failure. Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. Particularly for BCS class II substances, the bioavailability may be enhanced by increasing the solubility and dissolution rate of the drug in the gastro-intestinal fluids. The newer and novel technologies developed in recent year for troubleshooting such above problems. This review describes an overview of SEDDS as a capable approach to effectively capture the problem of poorly soluble molecules and give the novel approaches for evaluation of the SEDDS. Self-emulsifying drug delivery systems (SEDDS) are isotropic mixtures of drug, lipids and surfactants, usually with one or more hydrophilic co-solvents or co-emulsifiers.  

Modern drug delivery systems for targeting the posterior segment of the eye

2015 ◽  
Vol 21 (42) ◽  
pp. 6055-6069 ◽  
Author(s):  
Catalina Peptu ◽  
Marcel Popa ◽  
Corina Savin ◽  
Radu Popa ◽  
Lacramioara Ochiuz
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Posterior Segment ◽  
Modern Drug

Nanotechnology Advanced Strategies for the Management of Diabetes Mellitus

2019 ◽  
Vol 20 (10) ◽  
pp. 995-1007 ◽  
Author(s):  
Amira Mohamed Mohsen
Keyword(s):  
Diabetes Mellitus ◽  
Drug Delivery ◽  
Drug Targeting ◽  
Drug Delivery Systems ◽  
Polymeric Nanoparticles ◽  
Artificial Pancreas ◽  
Delivery Systems ◽  
The Novel ◽  
Site Of Action ◽  
Treatment Of Diabetes

Background:Medications currently available for the management of diabetes mellitus are inconvenient and have some limitations. Thus, investigations for novel approaches are needed to deliver and target antidiabetics safely to the site of action.Objective:The present review emphasizes the limitations of conventional antidiabetics and provides the recent progresses of nanotechnology in the treatment of diabetes mellitus with a special highlight on the novel nanocarriers methodologies employed as antidiabetic drug delivery systems.Methods:The potential nanocarriers employed for the treatment of diabetes comprise liposomes, niosomes, self-nanoemulsifying drug delivery systems, polymeric nanoparticles, gold nanoparticles, dendrimers and micelles. Herbal nanomedicine has also emerged to be a promising way for adequate delivery of herbal compounds. Other nanotechnology approaches involve the usage of oral insulin, inhalable insulin, artificial pancreas, and nanopump.Results:Nanocarriers have proved to lead a successful delivery of antidiabetic medications, aiming at drug targeting for enhanced efficacy and safety.Conclusion:These innovative generations of drug delivery systems have important benefits over conventionally existing ones. The future of nanotechnology in the management of diabetes is still open with several prospects and will be of pronounced significance.

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