HEAVY PRECIPITATION OCCURRENCE OVER KHERSON WEATHER STATION ACCORDING TO METEOROLOGICAL OBSERVATIONS AND ERA5 REANALYSIS

The paper presents the results of a study of heavy precipitation in the form of rain (> 30 mm/12 h) using data from the meteorological observations and atmospheric reanalysis ERA5 at the Kherson weather station in 2005-2021.Detected that at the Kherson there were only 19 cases of heavy rainfall, which occurred only in the warm half of the year with a maximum recurrence in July. Compared to 1961-1990, the number of heavy rains of 2005-2021 increased in July and June, and decreased in August.Determined that most of the real cases of increased precipitation in Kherson are in good agreement with the results of the ERA5 reanalysis, but in almost a third of the simulation episodes did not show heavy precipitation at the Kherson coordinates or their center was shifted.Heavy rains in Kherson were formed in a field of low atmospheric pressure, with a weak northwest wind and accompanied by thunderstorms.Clarified that most episodes of heavy rainfall in Kherson in 2005-2021 are associated with the movement of southern cyclones, others formed on the southern periphery of the anticyclone in the southwestern direction of the jet stream in the troposphere.

INVESTIGATED STRINGENT REQUIREMENTS FOR LIGHT INDUSTRY PRODUCTS AND PERMISSIBLE BURROWS OF ELECTRIC CHARGE

In article the strict requirements imposed to products of light industry by the international EKO-TEX-100 standard are considered, characteristics of the properties of biological safety of clothes produced from textile materials and a knitted cloth are given, the question of existence of an electro statistical charge in products of light industry against increase oncological and nervous a disease and its influence on health of the person is discussed.

SPATIOTEMPORAL DISTRIBUTION OF TORNADOES AND SQUALLS IN THE NORTH-WESTERN BLACK SEA REGION IN 2006-2020

Tornadoes and strong squalls are dangerous for almost all spheres of human life and the economy of the region. The degree of negative impact depends on their type, quantity, intensity, area of formation and geographical features of the territory. The article defines the dynamics of the number of tornadoes and strong squalls in the North-Western Black Sea region (Odessa, Nikolayev and Kherson regions of Ukraine) from 2006 to 2020.Geographical position of the south-west of Ukraine, synoptic processes and a variety of climatic conditions contribute to the frequent occurrence of severe convective phenomena and creating the extraordinary complexity of their space-time distribution. The study revealed current trends in the formation of dangerous convective phenomena in the south-west of Ukraine. One of the most squall-prone regions of Ukraine is the territory of the North-Western Black Sea region. During 2006-2020 there was an increase in the number of squalls and tornadoes in the North-Western Black Sea region in comparison with previous years.

EFFECTIVENESS AND SAFETY OF INTRA-ARTICULAR HYALURONIC ACID IN ATHLETES WITH ARTICULAR LESIONS: A MULTICENTER, PROSPECTIVE OBSERVATIONAL STUDY

Objective: To evaluate the effectiveness and safety of a novel intra-articular formulation of hyaluronic acid (HA) to treat athletes with articular lesions. Methods: Multicenter, prospective, interventional, observational study analyzing the clinical evolution of athletes who received 2 or 3 intra-articular injections of HA. The study was scheduled in Visit 1 (week 0), Visit 2 (week 1), Visit 3 (week 2), Visit 4 (week 3), and Visit 5 (end of follow up, week 24). The change in Visual Analog Scale (VAS) of pain and in Knee Injury and Osteoarthritis Outcome Score (KOOS) and the rate of return to physical activity were evaluated upon treatment initiation for up to 24 weeks. The incidence of adverse events was recorded throughout the study. Results: Sixty patients were recruited: 28 (46.7%) in the 2-injection group and 32 (53.3%) in the 3-injection group. Mean VAS gradually decreased across the visits, with statistically significant reductions in both groups from Visit 2 to Visit 3 and to Visit 5 (P < 0.0001). Inter-group differences in the change in VAS from Visit 2 to Visit 5 were statistically comparable (P = 0.8271). At Visit 5, the KOOS of all subscales statistically improved in both treatment groups. At the end of follow-up (Visit 5), 75.9% of patients returned to sport in the overall population. Only one patient reported an adverse event. Conclusion: This novel formulation of HA is effective and safe for at least 24 weeks, resulting in a promising treatment option for athletes with articular lesions.

ANALYSIS OF ADVERSE EVENTS AFTER IMMUNIZATION WITH VACCINES AGAINST Sars-Cov-2

Although the WHO-recommended coronavirus vaccines are safe and effective, vaccines provide new information to healthcare professionals about the extent and nature of adverse reactions to these drugs. The aim of the study is supplementing the available data on adverse reactions of vaccines on the example of the experience of vaccination of the teaching staff of the Cherkasy Medical Academy with vaccines COVISHIELD and COMIRNATY. Information for this study was collected retrospectively through a survey of 72 employees of the Cherkasy Medical Academy who were vaccinated with the COVISHIELD vaccine (first dose); 67 workers vaccinated with AstraZeneca (second dose); 54 workers who were vaccinated with COMIRNATY vaccine (first dose); 52 people vaccinated with this vaccine (second dose). The study confirmed that among the local side effects, the most common were pain at the injection site, among the systemic - fever, weakness, fatigue and drowsiness, headache, muscle pain, chills. Most of the side effects were most pronounced in young people, more often in women than in men.

RESEARCH OF ADSORPTION AFLATOXINS BY TECHNICAL LIGNIN

Aflatoxins represent aggressive group of mycotoxins. They are really toxic, carcinogenic and dangerous for human health. There are mechanical, physical and chemical methods for their detoxification. Aflatoxins could be also neutralized by means of various adsorbents as well. We do some research work in the direction of aflatoxin adsorption by presence of lignin, which is quite affordable and gives an effective result.

DIAGNOSTIC TACTICS FOR TRANSCONDYLAR AND SUPRACONDYLAR FRACTURES OF THE HUMERUS IN CHILDREN

Transcondylar and supracondylar fractures of the humerus in children are one of the most relevant and still not completely solved problems of modern pediatric traumatology. In the problem of condylar and supraorbital fractures of the humerus, the issues of diagnosis, choice of indications for surgical revision of the vascular-nervous bundle of the elbow area in this pathology are insufficiently covered. To solve the problems of the study, we analyzed the treatment of 313 victims with transcondylar and supracondylar fractures of the humerus, which were treated at the City Children's Clinical Hospital in Lviv in the period from 2013 to 2018. The structure of the distribution of arrays on the basis of rotational displacement in condylar fractures of the humerus is dominated by displacement up to 30°, which in the first group was found in 61.8% of cases, and in the second group - 69.2% of cases. The share of severe rotational displacements in the structure of group arrays is almost the same in both observation groups: 29.1% in the first group and 29.5% in the second group. Analysis of the proportion of extremely severe rotational displacements up to 90° in the structure of group arrays revealed that such victims were 7 times more among the victims of the first group than among the victims of the second group, due to the use of the proposed unified protocol scheme for diagnosis and treatment humeral fractures in pediatric patients, which avoids or reduces the difference in the occurrence of secondary displacements.

INFLUENCE ANTIOMOTOXIC PREPARATIONS ON UNSPECIFIC REACTION OF ADAPTATION OF ORGANISM

Effectiveness of Heel firm antihomotoxic preparation on unspecific adaptation reactions of organism was studied in this work. The main work was being done on the base of Georgian LLS of Physical Culture and on the base of Center of Treatment, Tbilisi. 57 patients 19-58 of age were taken for the investigation. They were divided into two groups. Group A (30 person) was prescribed antiohomotoxic preparations dosage according to general rules of usage of Heel firm preparation. Control and correction of the dosage of Heel firm preparation was making of croup B (27 persons) once a week. By its phone parameters of white blood group A and B didn’t have truthfully differences (p˃0,05). The possibility to model the resistance of organism with putting an antihomotoxic preparation was established with using of parameters of white blood. The new approach to individual dosage of antihomotoxic preparation was worked out in treatment of such diseases as gastritis, colitis, cystitis, adnexitis, thrombophlebitis, bronchial asthma, arthritis.

INFLUENCE ANTIOMOTOXIC PREPARATIONS ON UNSPECIFIC REACTION OF ADAPTATION OF ORGANISM

Effectiveness of Heel firm antihomotoxic preparation on unspecific adaptation reactions of organism was studied in this work. The main work was being done on the base of Georgian LLS of Physical Culture and on the base of Center of Treatment, Tbilisi. 57 patients 19-58 of age were taken for the investigation. They were divided into two groups. Group A (30 person) was prescribed antiohomotoxic preparations dosage according to general rules of usage of Heel firm preparation. Control and correction of the dosage of Heel firm preparation was making of croup B (27 persons) once a week. By its phone parameters of white blood group A and B didn’t have truthfully differences (p˃0,05). The possibility to model the resistance of organism with putting an antihomotoxic preparation was established with using of parameters of white blood. The new approach to individual dosage of antihomotoxic preparation was worked out in treatment of such diseases as gastritis, colitis, cystitis, adnexitis, thrombophlebitis, bronchial asthma, arthritis.

СВИНЦОВАЯ ЭКСПОЗИЦИЯ КАК ПРЕДПОСЫЛКА ОГРАНИЧЕНИЯ РЕАЛИЗАЦИИ МАКСИМАЛЬНОЙ ФИЗИЧЕСКОЙ АКТИВНОСТИ

As a result of man’s technological activities, numerous quantities of lead and its compounds are spread into the environment annually. The long-term effects of low doses of lead on the lungs, heart muscle and the transport function of erythrocytes were investigated. The study results indicate that long-term intake of small doses of lead, even in the absence of visible clinical manifestations, causes distinct structural changes and therefore, functional changes in the heart muscle, respiratory system, reduces the transport function of erythrocytes, and also possibly limiting the oxygen transport in myocytes and its deposition in tissues and diffusion into cells. There is no doubt that these changes will limit the ability to maximize the realization of physical activity.