scholarly journals Blood pressure lowering and anti-fibrotic effect of zinc specific chelator-tetraethylthiuram disulfide in rat model of L-NAME-induced hypertension

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Mysuru Natarajan Savitha ◽  
Supriya Sarkar ◽  
Kanve Nagaraj Suvilesh ◽  
Shravan Kumar S L ◽  
Bannikuppe Sannanaik Vishwanath
Keyword(s):  
Blood Pressure ◽  
Rat Model ◽  
Blood Pressure Lowering ◽  
Induced Hypertension ◽  
Pressure Lowering ◽  
Tetraethylthiuram Disulfide

scholarly journals BLOOD PRESSURE LOWERING EFFECT OF POLYHERBAL PREPARATION CONTAINING ALLIUM SATIVUM, BELERICAE FRUCTUS, CURCUMA AERUGINOSA, AND AMOMI FRUCTUS ON RAT MODEL OF HYPERTENSION

2019 ◽  
pp. 311-314 ◽  
Author(s):  
DWI ARIS AGUNG NUGRAHANINGSIH ◽  
SHOLIKHAH EN ◽  
MUSTOFA M ◽  
YULIANI FS ◽  
PURWONO S ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Rat Model ◽  
Allium Sativum ◽  
Negative Control ◽  
Control Group ◽  
Blood Pressure Lowering ◽  
Blood Pressure Lowering Effect ◽  
Lowering Effect ◽  
Treatment Dose ◽  
Pressure Lowering

Objective: The study aimed to investigate the blood pressure lowering effect of the polyherbal preparation contains Allium sativum, Belericae fructus, Curcuma aeruginosa, and Amomi fructus in the animal model of hypertension. Methods: Deoxycorticosterone acetate uninephrectomy salt rat model was used to develop hypertension model. Hypertensive rats were divided into five groups that were no treatment (negative control group [NEG]), hydrochlorothiazide treatment, polyherbal preparation 63 mg/kg treatment (DOSE 1), polyherbal preparation 126 mg/kg treatment (DOSE 2), and polyherbal preparation 252 mg/kg treatment (DOSE 3). The treatment was started after hypertension developed and given for 3 weeks. Results: The result showed that the mean of systolic blood pressure in DOSE 2 group was significantly lower compared with those on NEG group (145.86 mmHg vs. 174.71 mmHg, p<0.05). Conclusion: Our study provides evidence to support the use of the polyherbal preparation containing A. sativum, B. fructus, C. aeruginosa, and A. fructus for lowering blood pressure.

Blood Pressure Lowering Effect of an Olive Leaf Extract {Olea europaed) in L-NAME Induced Hypertension in Rats

2011 ◽  
Vol 52 (11) ◽  
pp. 797-802 ◽  
Author(s):  
Mohamed Khayyal ◽  
Mona El-Ghazaly ◽  
Dalai Abdallah ◽  
Noha Nassar ◽  
Samuel Okpanyi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Leaf Extract ◽  
Blood Pressure Lowering ◽  
Olive Leaf ◽  
Blood Pressure Lowering Effect ◽  
Olive Leaf Extract ◽  
Lowering Effect ◽  
Induced Hypertension ◽  
Pressure Lowering

scholarly journals Targeting of hepatic angiotensinogen using chemically modified siRNAs results in significant and sustained blood pressure lowering in a rat model of hypertension

2013 ◽  
Vol 37 (5) ◽  
pp. 405-412 ◽  
Author(s):  
Jeffrey Olearczyk ◽  
Sheng Gao ◽  
Marianne Eybye ◽  
Satyasri Yendluri ◽  
Lori Andrews ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Rat Model ◽  
Blood Pressure Lowering ◽  
Chemically Modified ◽  
Pressure Lowering
Sign in / Sign up

Export Citation Format

Share Document