Induced Hypothermia for Infants With Hypoxic- Ischemic Encephalopathy Using a Servo-Controlled Fan: An Exploratory Pilot Study

PEDIATRICS ◽  
2009 ◽  
Vol 123 (6) ◽  
pp. e1090-e1098 ◽  
Author(s):  
A. Horn ◽  
C. Thompson ◽  
D. Woods ◽  
A. Nel ◽  
A. Bekker ◽  
...  
Keyword(s):  
Pilot Study ◽  
Hypoxic Ischemic Encephalopathy ◽  
Induced Hypothermia ◽  
Ischemic Encephalopathy

scholarly journals Automated EEG background analysis to identify neonates with hypoxic-ischemic encephalopathy treated with hypothermia at risk for adverse outcome: A pilot study

2019 ◽  
Vol 60 (1) ◽  
pp. 50-58 ◽  
Author(s):  
Anneleen Dereymaeker ◽  
Vladimir Matic ◽  
Jan Vervisch ◽  
Perumpillichira J. Cherian ◽  
Amir H. Ansari ◽  
...  
Keyword(s):  
At Risk ◽  
Pilot Study ◽  
Adverse Outcome ◽  
Hypoxic Ischemic Encephalopathy ◽  
Ischemic Encephalopathy

scholarly journals Correlation Between White Matter Injury Identified by Neonatal Diffusion Tensor Imaging and Neurodevelopmental Outcomes Following Term Neonatal Asphyxia and Therapeutic Hypothermia: An Exploratory Pilot Study

2019 ◽  
Vol 34 (10) ◽  
pp. 556-566 ◽  
Author(s):  
Gwendolyn J. Gerner ◽  
Eric I. Newman ◽  
V. Joanna Burton ◽  
Brenton Roman ◽  
Elizabeth A. Cristofalo ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Pilot Study ◽  
Therapeutic Hypothermia ◽  
Diffusion Tensor ◽  
White Matter Injury ◽  
Hypoxic Ischemic Encephalopathy ◽  
Group Differences ◽  
Neurodevelopmental Outcomes ◽  
Ischemic Encephalopathy

Aim: Hypoxic-ischemic encephalopathy is associated with damage to deep gray matter; however, white matter involvement has become recognized. This study explored differences between patients and clinical controls on diffusion tensor imaging, and relationships between diffusion tensor imaging and neurodevelopmental outcomes. Method: Diffusion tensor imaging was obtained for 31 neonates after hypoxic-ischemic encephalopathy treated with therapeutic hypothermia and 10 clinical controls. A subgroup of patients with hypoxic-ischemic encephalopathy (n = 14) had neurodevelopmental outcomes correlated with diffusion tensor imaging scalars. Results: Group differences in diffusion tensor imaging scalars were observed in the putamen, anterior and posterior centrum semiovale, and the splenium of the corpus callosum. Differences in these regions of interest were correlated with neurodevelopmental outcomes between ages 20 and 32 months. Conclusion: Therapeutic hypothermia may not be a complete intervention for hypoxic-ischemic encephalopathy, as neonatal white matter changes may continue to be evident, but further research is warranted. Patterns of white matter change on neonatal diffusion tensor imaging correlated with neurodevelopmental outcomes in this exploratory pilot study.

Induced Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy: Pathophysiology, Current Treatment, and Nursing Considerations

2011 ◽  
Vol 30 (1) ◽  
pp. 29-36 ◽  
Author(s):  
DeLinda Jo Cooper
Keyword(s):  
Brain Injury ◽  
Healing Process ◽  
Current Treatment ◽  
Therapeutic Interventions ◽  
Hypoxic Ischemic Encephalopathy ◽  
Second Phase ◽  
Induced Hypothermia ◽  
Compensatory Mechanism ◽  
Neuroprotective Strategy ◽  
Ischemic Encephalopathy

AbstractHypoxic-ischemic encephalopathy (HIE) can lead to devastating neurodevelopmental consequences such as cerebral palsy, seizure disorders, and significant developmental delays. HIE in the newborn is often the result of a hypoxic event, such as uterine rupture, placental abruption, or cord prolapse. Biphasic brain injury occurs in HIE. The first phase involves activation of the sympathetic nervous system as a compensatory mechanism. The second phase, known as reperfusion brain injury, occurs hours later. Induced hypothermia, a neuroprotective strategy for treating HIE, targets the second phase to prevent reperfusion injury. NICU nurses are in a unique position to detect patient instability and to maintain the therapeutic interventions that contribute to the healing process. This article highlights the significant role nurses play in the management of infants diagnosed with HIE who are treated with induced hypothermia.

Perinatal infection and hypoxic-ischemic encephalopathy: a pilot study

2014 ◽  
Vol 29 (1) ◽  
pp. 140-142 ◽  
Author(s):  
Amaia Cilla ◽  
Juan Arnaez ◽  
Joaquín Suarez ◽  
Gregoria Megias ◽  
María Cabrerizo ◽  
...  
Keyword(s):  
Pilot Study ◽  
Hypoxic Ischemic Encephalopathy ◽  
Perinatal Infection ◽  
Ischemic Encephalopathy

scholarly journals Effects of Hypoxic-Ischemic Encephalopathy and Whole-Body Hypothermia on Neonatal Auditory Function: A Pilot Study

2008 ◽  
Vol 25 (07) ◽  
pp. 435-441 ◽  
Author(s):  
Ulrike Mietzsch ◽  
Nehal Parikh ◽  
Amber Williams ◽  
Seetha Shankaran ◽  
Robert Lasky
Keyword(s):  
Pilot Study ◽  
Hypoxic Ischemic Encephalopathy ◽  
Whole Body ◽  
Auditory Function ◽  
Ischemic Encephalopathy

A Pilot Study of Soluble Form of LOX-1 as a Novel Biomarker for Neonatal Hypoxic-Ischemic Encephalopathy

2019 ◽  
Vol 206 ◽  
pp. 49-55.e3 ◽  
Author(s):  
Tomohisa Akamatsu ◽  
Takehiro Sugiyama ◽  
Yoshinori Aoki ◽  
Ken Kawabata ◽  
Masaki Shimizu ◽  
...  
Keyword(s):  
Pilot Study ◽  
Hypoxic Ischemic Encephalopathy ◽  
Soluble Form ◽  
Ischemic Encephalopathy
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