THE USE OF EXTRACORPOREAL HEMODIALYSIS IN THE TREATMENT OF SALICYLATE INTOXICATION IN A 2-YEAR-OLD CHILD

PEDIATRICS ◽  
1959 ◽  
Vol 24 (4) ◽  
pp. 540-543
Author(s):  
Norton Spritz ◽  
Thomas J. Fahey ◽  
David D. Thompson ◽  
Albert L. Rubin

The procedure employed in the dialysis of a 13 kg boy with salicylate intoxication is described. Clinical and chemical data are presented which demonstrate the effectiveness and safety of this procedure. The arguments in favor of dialysis rather than exchange transfusion in the treatment of salicylate intoxication are discussed and the indications for the use of hemodialysis are enumerated.

PEDIATRICS ◽  
1962 ◽  
Vol 29 (3) ◽  
pp. 442-447
Author(s):  
J. A. James ◽  
Lewis Kimbell ◽  
William T. Read

Exchange transfusion, hemodialysis and peritoneal dialysis with albumin and conventional dialysis solutions was carried out in dogs following the administration of a standard dose of sodium salicylate intravenously. Hemodialysis was the most efficient method of removing salicylate, about 50% of the dose injected being removed during a 4-hour period. Exchange transfusion and peritoneal lavage were considerably less efficient. Peritoneal lavage with 5% albumin solution was more effective than lavage with an equal volume of conventional dialysis solution, but absorption of albumin from the peritoneum took place unless additional dextrose was added to the solution. The amount of salicylate excreted in the urine during the period of study sometimes exceeded that removed by peritoneal dialysis or exchange transfusion. Some clinical implications of these studies are discussed.


1960 ◽  
Vol 57 (5) ◽  
pp. 715-720 ◽  
Author(s):  
Sanford L. Leikin ◽  
George C. Emmanouilides

PEDIATRICS ◽  
1961 ◽  
Vol 27 (4) ◽  
pp. 603-613
Author(s):  
William E. Segar ◽  
Robert K. Gibson ◽  
Robert Rhamy

Ten infants and children ranging in age from 3 days to 34 months have been treated with peritoneal dialysis. All 10 were anuric on severely oliguric. Three had salicylate intoxication, and three had boric acid poisoning as additional complications. Three of the 10 children, including the only patient with irreversible renal disease, died. All seven who survived made complete and uncomplicated recoveries from their acute illness. One now has evidence of residual renal damage. The technique of peritoneal dialysis is described and the indications, contraindications and complications are discussed. The data presented indicate that peritoneal dialysis is an effective type of dialysis, that it is safe, that it can be accomplished with a minimum of equipment and that a highly trained team is not essential for its efficient use. It is superior to exchange transfusion in the treatment of most types of poisonings and is the only practical procedure currently available by which dialysis of an anuric infant or small child can be accomplished.


Author(s):  
Karen A. Katrinak ◽  
David W. Brekke ◽  
John P. Hurley

Individual-particle analysis is well established as an alternative to bulk analysis of airborne particulates. It yields size and chemical data on a particle-by-particle basis, information that is critical in predicting the behavior of air pollutants. Individual-particle analysis is especially important for particles with diameter < 1 μm, because particles in this size range have a disproportionately large effect on atmospheric visibility and health.


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