RENAL AMYLOIDOSIS RESULTING FROM A CHRONICALLY INFECTED BURN

PEDIATRICS ◽  
1963 ◽  
Vol 32 (5) ◽  
pp. 888-894
Author(s):  
Saul Hoffman ◽  
Bernard E. Simon ◽  
Robert A. Fischel ◽  
Donald Gribetz
Keyword(s):  
Nephrotic Syndrome ◽  
Renal Biopsy ◽  
Clinical Improvement ◽  
Short Duration ◽  
Unusual Case ◽  
White Male ◽  
Lower Extremities ◽  
Renal Amyloidosis ◽  
One Year

An interesting and unusual case of an 11-year-old white male with chronically infected burns of his lower extremities who developed amyloidosis and the nephrotic syndrome is reported. The case is considered from the following aspects: (1) the rarity of amyloidosis in burns, (2) the short duration between the onset of the primary disease and the amyloidosis, (3) the age of the patient, and (4) the striking clinical improvement of the renal manifestations after the treatment of the burn. The treatment of the burns, using homografts, and the importance of renal biopsy in the diagnosis and follow-up are also discussed. Addendum: A third renal biopsy was performed in August, 1963, about one year following the second one. The amount of amyloid seen in the glomeruli did not seem to have diminished.

Multiple Spinal Perimedullary Arteriovenous Fistulae Associated with the Parkes-Weber Syndrome

1998 ◽  
Vol 4 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Y. Niimi ◽  
U. Ito ◽  
O. Tone ◽  
K. Yoshida ◽  
S. Sato ◽  
...  
Keyword(s):  
Lower Extremities ◽  
Arteriovenous Fistulae ◽  
Left Posterior ◽  
Weber Syndrome ◽  
Long Term Follow Up ◽  
History Of ◽  
One Year ◽  
Polyvinyl Alcohol Particles

We present a rare case of multiple spinal perimedullary arteriovenous fistulae associated with the Parkes-Weber (PW) syndrome. A 31-year-old male known to have the PW syndrome involving the left leg since birth, presented with a 7-month-history of progressive myelopathy of the lower extremities and dysfunction of the bladder and bowel. Myelography demonstrated dilated intradural vessels. Angiography demonstrated two distinct single hole perimedullary arteriovenous fistulae near the conus at two different metameres. They were supplied by the left posterior spinal artery. The patient was treated by transarterial embolisation using polyvinyl alcohol particles, which resulted in venous side occlusion of the fistulae. After the treatment, the patient developed transient worsening of the spasticity of the lower extremities, and was treated by heparinization. After heparinization, the patient partially recovered from the pre-embolisation status of his myelopathy. The follow-up angiogram one year after the embolisation demonstrated persistent obliteration of both fistulae. At long-term follow-up, the patient can ambulate without assistance and work as a farmer.

scholarly journals Benign mixed tumour of the upper lip – Report of a rare case

2021 ◽  
Vol 2 (1) ◽  
pp. 149-155
Author(s):  
Maria C. Michali ◽  
Lentiona V. Basiari ◽  
Konstantina Ζ. Mparka ◽  
Ioannis D. Komnos
Keyword(s):  
Pleomorphic Adenoma ◽  
Unusual Case ◽  
Malignant Neoplasms ◽  
Upper Lip ◽  
Salivary Gland Tumours ◽  
Mobile Mass ◽  
One Year ◽  
Slow Growing ◽  
Mixed Tumours

Introduction: Pleomorphic adenomas are the most common non-malignant neoplasms of salivary gland tumours that present mixed histopathological patterns. The purpose of our study was to report an unusual case of a pleomorphic adenoma which was located in the upper lip that had been initially considered as cyst. Case report: The patient was a middle aged man who had a painless, slow-growing swelling in the upper lip. At first, the round-shaped and mobile mass was considered as cystic lesion. However during the operation, it was discovered instead of a cyst, an encapsulated solid tumour that demonstrated both epithelial and mesenchymal cells in histopathology and the diagnosis of pleomorphic adenoma was set. One year postoperatively the patient had no recurrence of tumour. Conclusions: Occurrence of intraoral lip swelling could be attributed, even rarely, to benign mixed tumours. Despite its nonmalignant features, these masses have a relatively low but still existing risk for recurrence or malignant transformation and thus in similar cases a systematic follow-up should be performed even years after surgery.

scholarly journals Unusual mandible fracture caused by metallic spear: case report and literature review

2020 ◽  
Vol 26 (2) ◽  
pp. 20
Author(s):  
Samuel Macedo Costa ◽  
Bruna Campos Ribeiro ◽  
Bernardo Barcelos Greco ◽  
Rodolfo César Gual ◽  
Alessandro Oliveira de Jesus ◽  
...  
Keyword(s):  
Unusual Case ◽  
Mandible Fracture ◽  
Operative Care ◽  
Surgical Incisions ◽  
The Face ◽  
Gun Shot ◽  
History Of ◽  
One Year ◽  
Water Sports

Spear gun projectiles injuries are are very rare and are usually related to lack of attention during water- sports or fishing practices. This study aims to describe an unusual case of facial injury associated with a mandibular fracture after a spear gun shot. A 38-years-old man was admitted with a history of penetrating injury on the face caused by an accidental shot from a spear gun. After the initial stabilization and examination, the patient was taken to the surgical room for the removal of the projectile. The post-operative care was uneventful and the patient was discharged with no concerns, being in follow-up for one year with no signs of infection or malocclusion. The surgical procedure should be done as soon as possible and the removal of the spear must be done carefully, under direct vision, with or without surgical incisions. Major complications can occur after spear injuries, therefore, the patient must be observed in the postoperative period and should maintain follow up until the end of the rehabilitative process.

Community psychiatric nurse aftercare for alcoholics

1991 ◽  
Vol 8 (1) ◽  
pp. 4-14 ◽  
Author(s):  
Diana G Patterson ◽  
Maureen W McCourt ◽  
Joyce R A Shiels
Keyword(s):  
Inpatient Treatment ◽  
Hospital Admissions ◽  
White Male ◽  
Rural Setting ◽  
Control Group ◽  
Psychiatric Nurse ◽  
Community Psychiatric ◽  
One Year ◽  
Outpatient Appointments

AbstractOne hundred and twenty-seven white male alcoholics, treated in a rural setting, were assigned to one of two groups. Seventy-three subjects received intensive aftercare by Community Psychiatric nurse and fifty-four control subjects received standard aftercare with outpatient appointments. Subjects were assessed one year after treatment. Fifty-four per cent of those given Community Psychiatric Nurse follow-up were completely abstinent compared with twenty per cent of those in the control group. Those receiving Community Psychiatric Nurse follow-up were less likely to have blackouts, hospital admissions or marital discord in the year following treatment. They were more likely to attend hospital meetings regularly. This form of aftercare is an effective way of maximising the benefits of expensive inpatient treatment.

scholarly journals Description of Renal Biopsy in Frequently Relapsing and Corticosteroid Non Responsive Nephrotic Syndrome in Childhood

2019 ◽  
Vol 28 (9-10) ◽  
pp. 192-9
Author(s):  
D. Bahrun ◽  
M. Nazir ◽  
K. Yangtjik N.
Keyword(s):  
Nephrotic Syndrome ◽  
Renal Biopsy ◽  
Crescentic Glomerulonephritis ◽  
Minimal Change Nephrotic Syndrome ◽  
The Other ◽  
Proliferative Glomerulonephritis ◽  
Steroid Resistant ◽  
Frequent Relapses ◽  
Diffuse Proliferative Glomerulonephritis

A study of 71 children with nephrotic syndrome admitted to the Department of Child Health, Medical School, Sriwijaya University Palembang General Hospital between November 1981 and November 1983 has been reported. Of the 71 children, there were 50 (70.4%) boys and 21 (29.6%) girls, in which 31 were less than 6 years of age. During the first eight weeks complete rem1sswn was found in 66 patients. The other five were steroid resistant. Among the 66 patients who responded to steroid, 61 had remission with the first 4 weeks. Further observation up to two years, 3 patients were still in remission, 36 had one relapse and 22 had frequent relapses. The other 5 patients, who had remission on the second 4 weeks, one had one relapse, two had frequent relapses and the other two were not available for follow up. Renal biopsy was performed in 31 patients. The representative results of the renal biopsy were found in only 20 patients : Eleven patients showed minimal change nephrotic syndrome (MCNS). Ten of these patients had frequent relapses while one patient was steroid resistant. Two had renal insufficiency. Three patients had focal glomerulosclerosis (FGS); two of them were frequently relapsing patients and the other one had steroid resistant. Four patients had mesangial proliferative glomerulonephritis (Mes. PGN). All of them had frequent relapses. One patient with diffuse proliferative glomerulonephritis (DPGN) was steroid resistant. One patient with crescentic glomerulonephritis (CrGN) was also steroid resistant.

scholarly journals An unusual case of cryoglobulinemic purpura in elderly patient

2015 ◽  
Vol 9 (1) ◽  
pp. 13-20
Author(s):  
Mauro Turrin
Keyword(s):  
Elderly Patient ◽  
Nephrotic Syndrome ◽  
Unusual Case ◽  
Mixed Cryoglobulinemia ◽  
Lymphoproliferative Disorders ◽  
Essential Mixed Cryoglobulinemia ◽  
Primary Sjögren Syndrome ◽  
High Prevalence ◽  
Neoplastic Disorders

Cryoglobulinemia is associated with infections, in particular chronic hepatitis C, autoimmune diseases, and lymphoproliferative disorders. Its frequency seems to be higher than is commonly considered, even in elderly patients.We describe the case of an elderly patient with diabetes, nephroangiosclerosis and purpura who presented marked and persistent increase in rheumatoid factor, hypocomplementemia and cryoglobulinemia with nephrotic disagreement unrelated to HCV. A thirteen‑month follow‑up showed neither immunorheumatologic nor neoplastic disorders. In literature, associations with hepatic pseudocyst is not described and a lack of association with HCV is very rare. Therefore, the hypothesis of “essential” mixed cryoglobulinemia (EMC) associated with nephrotic syndrome was formulated. Renal disease associated with EMC (unrelated to HCV) is characterized by the high prevalence of primary Sjögren syndrome and overt B‑cell non‑Hodgkin’s lymphoma for which repetitive clinical evaluation is necessary.

scholarly journals Renal biopsy in children with nephrotic syndrome: a study of histopathological pattern

2019 ◽  
Vol 6 (3) ◽  
pp. 1243
Author(s):  
Trupti A. Joshi ◽  
Amol K. Joshi
Keyword(s):  
Nephrotic Syndrome ◽  
Renal Biopsy ◽  
Minimal Change Disease ◽  
Health Care Centre ◽  
Cross Sectional ◽  
Mesangial Proliferation ◽  
True Incidence ◽  
Renal Biopsies ◽  
The Common ◽  
One Year

Background: Idiopathic nephrotic syndrome (INS) is a common childhood renal disease characterized by a remitting and relapsing course, associated with different histopathological subtypes. The true incidence of various histopathological subtypes of NS remains under estimated owing to the diversity in indication criteria for performing renal biopsies in pediatric population.Methods: This was a cross-sectional observational study in children with nephrotic syndrome at a tertiary health care centre. Total 22 children, with nephrotic syndrome, who underwent renal biopsy procedure during a period of one year, were enrolled for the study. Indications of renal biopsy were noted, and the histopathology reports were studied in detail.Results: In this study group, the most common indication for renal biopsy was “Atypical age (> 8years) of diagnosis in 45.5% (10/22) patients, followed by 22.7% (5/22) in “Children presenting with hypertension and hematuria”.The most common histopathological finding in these children was mesangial proliferative glomerulonephritis in 45.5% (10/22) patients followed by IgA nephropathy with mesangial proliferation in 22.72% (5/22) and minimal change disease in only 13.6% (3/22).Conclusions: This study highlights the occurrence of non-MCD as the common cause of INS in the children and denotes the significance of performing renal biopsies in children with INS for better prognostication.

scholarly journals Canine renal amyloidosis: A case report

2018 ◽  
Vol 74 (1) ◽  
pp. 6038-2018
Author(s):  
Barbara Szczepankiewicz ◽  
Urszula Pasławska ◽  
Maciej Grzegory ◽  
Paweł Jonkisz ◽  
Paulina Borecka ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Serum Amyloid A ◽  
Histopathological Examination ◽  
Kidney Tissue ◽  
Definitive Diagnosis ◽  
Renal Amyloidosis ◽  
Post Mortem ◽  
Amyloid A ◽  
Amyloid Deposits ◽  
One Year

Amyloidosis is a disease caused by the deposition of amorphous extracellular protein, leading to impaired kidney function. Canine and feline amyloidosis is associated with the deposition of AA protein. The disease is hereditary and is related to breed but not sex. Predisposed breeds include the Shar Pei dog and Abyssinian cat. Proteinuria resulting in hypoalbuminemia due to changes in renal glomeruli is the first clinical sign. In addition, a decreased appetite, anorexia, vomiting, lethargy, polyuria and polydipsia may be observed. In order to diagnose the disease, serum amyloid A levels may be measured. However, a definitive diagnosis is made on the basis of an intravital renal biopsy and the presence of amyloid in the histopathological examination. The main goal of treatment is to reduce inflammation and proteinuria. If nephrotic syndrome occurs, the prognosis is guarded to poor, and the majority of patients do not survive one year. The definitive diagnosis is based on the post-mortem examination, in which the presence of amyloid deposits is confirmed in the kidney tissue. We present the case of a 7-year-old female Shar Pei diagnosed with kidney amyloidosis, on the basis of which we have developed a prevention scheme for clinical practice..

Lupus-like membranous nephropathy. Is it lupus? Report of 5 cases in a reference hospital in Mexico

Lupus ◽  
2021 ◽  
pp. 096120332110135
Author(s):  
Luis Manuel Ramírez-Gómez ◽  
Ivette Ruiz-Leija ◽  
David Martínez-Galla ◽  
Jaime Antonio Borjas-García ◽  
Carlos Abud-Mendoza ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Lupus Nephritis ◽  
Renal Biopsy ◽  
Mycophenolic Acid ◽  
Lupus Erythematosus ◽  
Antinuclear Antibodies ◽  
Classification Criteria ◽  
Normal Limits ◽  
Extrarenal Manifestations

Introduction: Lupus nephritis requires antinuclear antibodies as classification criteria. There is a group of patients with nephrotic syndrome and conclusive histopathological findings for lupus nephritis, without classification criteria for systemic lupus erythematosus (SLE) or extrarenal manifestations. These groups of patients have been described as “lupus-like” nephritis or “renal-limited lupus nephritis”. Methods: Renal biopsy with histopathological evaluation with “full-house” immune-reactants in patients with negative antinuclear antibodies. Results: We report four cases with nephrotic syndrome and one with hematuria-proteinuria syndrome: two with impaired glomerular filtration rate and three with preserved renal function; urinary sediment with hematuria without dysmorphia and without extrarenal manifestations for autoimmune disease, negative antinuclear antibodies (ANA) and anti-double stranded DNA (anti-dsDNA); normal C3 and C4 complement levels. Renal biopsy in all cases was consistent for lupus nephritis class V. All patients received treatment as lupus nephritis protocol; only one case received induction with cyclophosphamide and methylprednisolone boluses, the rest received mycophenolic acid and prednisone as induction and maintenance. Two of the cases induced with mycophenolic acid relapsed, requiring cyclophosphamide for 6 months, achieving complete remission. All patients received renin-angiotensin-aldosterone system blockade and hydroxychloroquine. At follow-up, 4 cases still have negative antibodies and are without extrarenal manifestations for SLE classification criteria. The other case, during pregnancy several years after initial diagnosis, had preeclampsia with nephrotic proteinuria and a new determination of positive ANA and anti-dsDNA antibodies, complement levels below normal limits. Conclusion: The follow-up of patients with membranous glomerulopathy must be close; lupus like nephritis may be the first manifestation of the disease.

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