Maternal Alcohol Use and Infant Development

PEDIATRICS ◽  
1982 ◽  
Vol 70 (6) ◽  
pp. 931-934
Author(s):  
Nancy L. Golden ◽  
Robert J. Sokol ◽  
Betty R. Kuhnert ◽  
Sidney Bottoms
Keyword(s):  
Alcohol Use ◽  
Motor Development ◽  
Infant Development ◽  
Controlled Study ◽  
Fetal Alcohol ◽  
Maternal Alcohol ◽  
History Of ◽  
Alcohol Effects ◽  
And Control ◽  
Fetal Alcohol Effects

A prospective controlled study of the effect of fetal alcohol on infant development was performed. Twelve infants were identified as possibly having fetal alcohol effects based on the maternal history of alcohol abuse and the neonatal physical examination. Physical characteristics, growth, and development of these infants were compared with those of 12 control infants at birth and at a mean age of 12 months; control infants were matched for gestational age, sex, and race. Data were evaluated by descriptive statistics and analysis of differences between matched pairs of study and control infants. The results showed a significant correlation between the history of heavy antenatal maternal alcohol use and delayed mental and motor development, physical abnormalities, and growth retardation in the infants. This study suggests that infants with fetal alcohol effects can be correctly classified at birth and their outcome accurately predicted.

Environment, Genes, and Alcohol

PEDIATRICS ◽  
1983 ◽  
Vol 71 (6) ◽  
pp. 989-989
Author(s):  
PATRICK H. CASEY
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Recent Article ◽  
Infant Development ◽  
Controlled Study ◽  
Developmental Outcome ◽  
Fetal Alcohol ◽  
Alcohol Effects ◽  
Fetal Alcohol Effects

To the Editor.— The recent article by Golden et al1 on fetal alcohol syndrome (FAS) and infant development purpots to be a controlled study which suggests that infants with fetal alcohol effects can be classified at birth and that their developmental outcome can be accurately predicted. Although there are several problems in the interpretation of their data and conclusions, I would like to address a major methodologic flaw in this report which persists throughout the literature on FAS.

Effect of Prenatal Alcohol Exposure on Growth and Morphology of Offspring at 8 Months of Age

PEDIATRICS ◽  
1990 ◽  
Vol 85 (5) ◽  
pp. 748-752
Author(s):  
Nancy L. Day ◽  
Gale Richardson ◽  
Nadine Robles ◽  
Usha Sambamoorthi ◽  
Paul Taylor ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
Alcohol Effects ◽  
Prenatal Alcohol ◽  
Minor Physical Anomalies ◽  
Continuous Use ◽  
Fetal Alcohol Effects

In this prospective study of alcohol and other substance use during pregnancy, a cohort of women was interviewed at each trimester of pregnancy and when the offspring were 8 months of age. Data are presented concerning the outcome for 461 infants. A significant relationship was found between alcohol use during pregnancy and the growth and morphology of the offspring at the 8-month follow-up observation. Alcohol use during the second and third trimesters of pregnancy and continuous use of alcohol throughout pregnancy were significantly related to lower weight, length, and head circumference in the exposed infants at the follow-up observation. A significant increase in the risk of minor physical anomalies and fetal alcohol effects was also predicted by prenatal alcohol exposure.

Prevention of Fetal Alcohol Effects

PEDIATRICS ◽  
1982 ◽  
Vol 69 (6) ◽  
pp. 813-816
Author(s):  
Henry L. Rosett ◽  
Lyn Weiner
Keyword(s):  
Adverse Effects ◽  
Fetal Development ◽  
Critical Period ◽  
Critical Level ◽  
Fetal Alcohol ◽  
Maternal Alcohol ◽  
Alcohol Effects ◽  
Maternal Alcohol Abuse ◽  
Scientific Attention ◽  
Fetal Alcohol Effects

The effects of alcohol on fetal development have gained renewed scientific attention during the decade following identification and description of the fetal alcohol syndrome (FAS). An association between maternal alcohol abuse and growth retardation, physical anomalies, and developmental delay in the fetus has been demonstrated through clinical, epidemiologic, and experimental evidence. The effects of various doses at different stages of gestation remain unclear. Is there a critical level of alcohol consumption that regularly produces the full FAS? Is there a lower threshold below which there is no danger of adverse effects? Is there one critical period during gestation or can adverse effects occur throughout pregnancy?

Prenatal Exposure to Alcohol: Effect on Infant Growth and Morphologic Characteristics

PEDIATRICS ◽  
1989 ◽  
Vol 84 (3) ◽  
pp. 536-541 ◽  
Author(s):  
Nancy L. Day ◽  
Dorcie Jasperse ◽  
Gale Richardson ◽  
Nadine Robles ◽  
Usha Sambamoorthi ◽  
...  
Keyword(s):  
Substance Use ◽  
Birth Weight ◽  
Prospective Study ◽  
First Trimester ◽  
Fetal Alcohol ◽  
Maternal Alcohol ◽  
Morphologic Characteristics ◽  
The Status ◽  
Alcohol Effects ◽  
Fetal Alcohol Effects

In this prospective study of alcohol and other substance use during pregnancy, a cohort of 650 women was interviewed at each trimester of pregnancy. Data are presented concerning the status of 595 live singleton births. A relationship was demonstrated between prenatal maternal alcohol use and growth and morphologic abnormalities in the offspring. Low birth weight, decreased head circumference and length, and an increased rate of fetal alcohol effects were all found to be significantly correlated with exposure to alcohol during the first 2 months of the first trimester.

Fetal Alcohol Effects

2013 ◽  
pp. 1277-1277
Author(s):  
Tracey Ward ◽  
Raphael Bernier ◽  
Cora Mukerji ◽  
Danielle Perszyk ◽  
James C. McPartland ◽  
...  
Keyword(s):  
Fetal Alcohol ◽  
Alcohol Effects ◽  
Fetal Alcohol Effects
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