Otitis Media in Neonatal Intensive Care Unit Graduates: A 1-Year Prospective Study

PEDIATRICS ◽  
1988 ◽  
Vol 82 (1) ◽  
pp. 44-49
Author(s):  
Judith S. Gravel ◽  
Cecelia M. McCarton ◽  
Robert J. Ruben

A group of 46 high-risk infants (graduates of a neonatal intensive care unit) and 19 full-term infants were observed prospectively for middle ear status beginning at 40 weeks' postconceptional age. All infants were born to families living in low socioeconomic urban neighborhoods. Pneumootoscopy was used to determine the presence or absence of middle ear effusion during periodic medical and nonmedical visits throughout a 1-year period. Of all infants studied, 91% had at least one episode of otitis media with effusion during the observation interval. There were no differences in the percentages of visits during which high-risk and full-term infants experienced either normal middle ears bilaterally or otitis media with effusion in one or both ears. Furthermore, the age of onset of otitis media with effusion was similar for the two groups of babies. No differences were found between boys and girls in the age of onset for otitis media or in the percentage of visits at which otitis media with effusion was detected. Hispanic infants experienced their initial episode at significantly younger ages than did black infants in the sample. Both groups had similar percentages of visits attributable to otitis media with effusion during the observation period. The results indicate a high incidence among the infants studied and similar otologic courses for neonatal intensive care unit graduates and full-term infants during the first year of life.

2021 ◽  
Vol 8 (2) ◽  
pp. 107-108
Author(s):  
Purbasha Mishra ◽  
Pankaj Kumar Mohanty ◽  
Tapas Kumar Som ◽  
Mohammad Zakiulla ◽  
Tanushree Sahoo

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Tiantian Xiao ◽  
Qi Ni ◽  
Huiyao Chen ◽  
Huijun Wang ◽  
Lin Yang ◽  
...  

PEDIATRICS ◽  
2004 ◽  
Vol 113 (Supplement_2) ◽  
pp. 676-678 ◽  
Author(s):  
Edward Z. Tronick ◽  
Karen Olson ◽  
Rebecca Rosenberg ◽  
Lisa Bohne ◽  
Jing Lu ◽  
...  

Descriptive statistics for the Neonatal Intensive Care Unit Network Neurobehavioral Scale summary scores are provided for a sample of 125 full-term, healthy 1- to 2-day-old infants. The study sample is described, including demographic characteristics and infant and maternal medical characteristics. Descriptive statistics and percentiles are provided for the Neonatal Intensive Care Unit Network Neurobehavioral Scale summary scores. These tables can be used as quasinorms for comparison with other infants of this age.


2019 ◽  
Vol 70 (12) ◽  
pp. 2553-2560
Author(s):  
Ashley M Rooney ◽  
Kathryn Timberlake ◽  
Kevin A Brown ◽  
Saumya Bansal ◽  
Christopher Tomlinson ◽  
...  

Abstract Background Discontinuation of inappropriate antimicrobial therapy is an important target for stewardship intervention. The drug and duration-dependent effects of antibiotics on the developing neonatal gut microbiota needs to be precisely quantified. Methods In this retrospective, cross-sectional study, we performed 16S rRNA sequencing on stool swab samples collected from neonatal intensive care unit patients within 7 days of discontinuation of therapy who received ampicillin and tobramycin (AT), ampicillin and cefotaxime (AC), or ampicillin, tobramycin, and metronidazole (ATM). We compared taxonomic composition within term and preterm infant groups between treatment regimens. We calculated adjusted effect estimates for antibiotic type and duration of therapy on the richness of obligate anaerobes and known butyrate-producers in all infants. Results A total of 72 infants were included in the study. Term infants received AT (20/28; 71%) or AC (8/28; 29%) with median durations of 3 and 3.5 days, respectively. Preterm infants received AT (32/44; 73%) or ATM (12/44; 27%) with median durations of 4 and 7 days, respectively. Compositional analyses of 67 stool swab samples demonstrated low diversity and dominance by potential pathogens. Within 1 week of discontinuation of therapy, each additional day of antibiotics was associated with lower richness of obligate anaerobes (adjusted risk ratio [aRR], 0.84; 95% confidence interval [CI], .73–.95) and butyrate-producers (aRR, 0.82; 95% CI, .67–.97). Conclusions Each additional day of antibiotics was associated with lower richness of anaerobes and butyrate-producers within 1 week after therapy. A longitudinally sampled cohort with preexposure sampling is needed to validate our results.


2013 ◽  
Vol 3 (1) ◽  
pp. 35 ◽  
Author(s):  
Yoshinori Morita ◽  
Hideo Iwakura ◽  
Harumi Ohtsuka ◽  
Yoichi Kohno ◽  
Naoki Shimojo

2020 ◽  
Vol 179 (12) ◽  
pp. 1949-1955 ◽  
Author(s):  
Maria Elena Cavicchiolo ◽  
Daniele Trevisanuto ◽  
Elisabetta Lolli ◽  
Veronica Mardegan ◽  
Anna Maria Saieva ◽  
...  

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